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Found 54 of ic50 for UniProtKB: P14416
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268430((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421355(CHEMBL289955)
Affinity DataIC50:  1.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268433((S)-2-((S)-2-amino-N-methyl-3-phenylpropanamido)-N...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421358(CHEMBL45141)
Affinity DataIC50:  1.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421357(CHEMBL297168)
Affinity DataIC50:  2.30nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421355(CHEMBL289955)
Affinity DataIC50:  2.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50:  3.20nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50:  3.20nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421356(CHEMBL43313)
Affinity DataIC50:  3.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421356(CHEMBL43313)
Affinity DataIC50:  3.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50:  3.80nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50:  3.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421357(CHEMBL297168)
Affinity DataIC50:  3.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268432((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50:  6nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50:  6nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268377((S)-2-amino-N-((S)-1-((S)-1-amino-3-(3-tert-butyl-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50:  6.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50:  6.5nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108830(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Affinity DataIC50:  7nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50:  7.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50:  7.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50:  8.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50:  8.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50:  8.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50:  9.10nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108832(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268378((S)-2-amino-N-((3S,6S)-3-(3-tert-butyl-4-hydroxybe...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268376((S)-2-amino-N-((S)-2-((S)-1-amino-3-(3-tert-butyl-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108833(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)
Affinity DataIC50:  17nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268431((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268429((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108830(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Affinity DataIC50:  33nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108829(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Affinity DataIC50:  33nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268428((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108829(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Affinity DataIC50:  59nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108833(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)
Affinity DataIC50:  65nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421353(CHEMBL406517)
Affinity DataIC50:  71nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421353(CHEMBL406517)
Affinity DataIC50:  71nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421352(CHEMBL281952)
Affinity DataIC50:  155nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421352(CHEMBL281952)
Affinity DataIC50:  155nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268427((S)-2-amino-N-((S)-1-((S)-1-amino-3-(3-tert-butyl-...)
Affinity DataIC50:  185nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM85846(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)
Affinity DataIC50:  224nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM85846(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)
Affinity DataIC50:  224nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50:  302nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50:  302nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108836(2-Amino-N-[2-(3,5-di-tert-butyl-4-hydroxy-benzyl)-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108837(2-Amino-N-[2-(4-sec-butoxy-benzyl)-3,7,14-trioxo-1...)
Affinity DataIC50:  480nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108828(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108827(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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