Affinity DataKd: 0.0360nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectrosco...More data for this Ligand-Target Pair
Affinity DataKd: 0.0380nMAssay Description:Binding affinity to human MDM2 by by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 0.0450nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0450nMAssay Description:Binding affinity to human MDM2 by by surface plasmon resonace spectroscopyMore data for this Ligand-Target Pair
Affinity DataKd: 0.150nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.220nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 0.257nMAssay Description:Binding affinity to human MDM2 by by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 0.392nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectrosco...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by surface plasmon resonance binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.450nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 0.920nMAssay Description:Binding affinity to human DM2 (17 to 125 residues)More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human MDM2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Inhibition of human MDM2 L33E mutant (14 to 111 residues) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding affinity to HDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to N-terminal TEV/GST-fused human MDM2 (22 to 110 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation consta...More data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 9.80nMAssay Description:Binding affinity to HDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to recombinant human GST-tagged HDM2More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hr by DTT reagent based ...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by surface plasmon resosnance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to 15N-labeled MDM2 (unknown origin) by 2D 1H-15N HSQC NMR spectroscopic methodMore data for this Ligand-Target Pair
Affinity DataKd: 37.8nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding affinity to human MDM2 (17 to 125 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 57nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
Affinity DataKd: 57nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to recombinant human MDM2 expressed in Escherichia coli DH5alpha assessed as inhibition of MDM2/p53 protein-protein interactionMore data for this Ligand-Target Pair
Affinity DataKd: 62nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding affinity to human HDM2More data for this Ligand-Target Pair
Affinity DataKd: 73nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
Affinity DataKd: 80nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Displacement of fluorescein-labeled p53 peptide from HDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 90nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair