BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 117 hits of ec50 for UniProtKB: P04545   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301476
PNG
(US10131673, Compound P3)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCC[C@H]1c1cc2nc3CCCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C28H36N6O4S/c1-19-10-11-23(31-39(2,36)37)21(17-19)28(35)33-12-6-5-9-25(33)24-18-26-29-22-8-4-3-7-20(22)27(34(26)30-24)32-13-15-38-16-14-32/h10-11,17-18,25,31H,3-9,12-16H2,1-2H3/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.562n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301499
PNG
(N-(2-(2-(9-(dimethylamino)-5-methyl-5,6,7,8-tetrah...)
Show SMILES CN(C)c1c2CCCN(C)c2nc2cc(nn12)C1CCCCN1C(=O)c1cc(C)ccc1NS(C)(=O)=O
Show InChI InChI=1S/C26H35N7O3S/c1-17-11-12-20(29-37(5,35)36)19(15-17)26(34)32-14-7-6-10-22(32)21-16-23-27-24-18(9-8-13-31(24)4)25(30(2)3)33(23)28-21/h11-12,15-16,22,29H,6-10,13-14H2,1-5H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.58n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301488
PNG
(N-(2-(2-(9-(dimethylamino)-5,6,7,8-tetrahydropyraz...)
Show SMILES CN(C)c1c2CCCCc2nc2cc(nn12)C1CCCCN1C(=O)c1cc(C)ccc1NS(C)(=O)=O
Show InChI InChI=1S/C26H34N6O3S/c1-17-12-13-21(29-36(4,34)35)19(15-17)26(33)31-14-8-7-11-23(31)22-16-24-27-20-10-6-5-9-18(20)25(30(2)3)32(24)28-22/h12-13,15-16,23,29H,5-11,14H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.78n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301474
PNG
(US10131673, Compound P1)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C28H36N6O4S/c1-19-10-11-23(31-39(2,36)37)21(17-19)28(35)33-12-6-5-9-25(33)24-18-26-29-22-8-4-3-7-20(22)27(34(26)30-24)32-13-15-38-16-14-32/h10-11,17-18,25,31H,3-9,12-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.78n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301500
PNG
(N-(2-(2-(5-(dimethylamino)-9-methyl-6,7,8,9-tetrah...)
Show SMILES CN(C)c1nc2cc(nn2c2N(C)CCCc12)C1CCCCN1C(=O)c1cc(C)ccc1NS(C)(=O)=O
Show InChI InChI=1S/C26H35N7O3S/c1-17-11-12-20(29-37(5,35)36)19(15-17)26(34)32-14-7-6-10-22(32)21-16-23-27-24(30(2)3)18-9-8-13-31(4)25(18)33(23)28-21/h11-12,15-16,22,29H,6-10,13-14H2,1-5H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.04n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301480
PNG
(BDBM301481 | US10131673, Compound P7)
Show SMILES Cc1cccc2nc(NS(C)(=O)=O)nc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C29H36N8O3S/c1-19-8-7-11-22-26(19)27(32-29(31-22)34-41(2,38)39)36-13-6-5-12-24(36)23-18-25-30-21-10-4-3-9-20(21)28(37(25)33-23)35-14-16-40-17-15-35/h7-8,11,18,24H,3-6,9-10,12-17H2,1-2H3,(H,31,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 6.03n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301475
PNG
(US10131673, Compound P2)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCC[C@@H]1c1cc2nc3CCCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C28H36N6O4S/c1-19-10-11-23(31-39(2,36)37)21(17-19)28(35)33-12-6-5-9-25(33)24-18-26-29-22-8-4-3-7-20(22)27(34(26)30-24)32-13-15-38-16-14-32/h10-11,17-18,25,31H,3-9,12-16H2,1-2H3/t25-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 13.2n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301482
PNG
(US10131673, Compound P9)
Show SMILES Cc1ccc2nc(NS(C)(=O)=O)nc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c2c1
Show InChI InChI=1S/C29H36N8O3S/c1-19-10-11-23-21(17-19)27(32-29(31-23)34-41(2,38)39)36-12-6-5-9-25(36)24-18-26-30-22-8-4-3-7-20(22)28(37(26)33-24)35-13-15-40-16-14-35/h10-11,17-18,25H,3-9,12-16H2,1-2H3,(H,31,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 13.5n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301515
PNG
(N,N,5-trimethyl-2-(1-(5-methylquinazolin-4-yl)pipe...)
Show SMILES CN(C)c1c2CCN(C)c2nc2cc(nn12)C1CCCCN1c1ncnc2cccc(C)c12
Show InChI InChI=1S/C25H30N8/c1-16-8-7-9-18-22(16)24(27-15-26-18)32-12-6-5-10-20(32)19-14-21-28-23-17(11-13-31(23)4)25(30(2)3)33(21)29-19/h7-9,14-15,20H,5-6,10-13H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 16.6n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301492
PNG
(N-(2-(2-(9-amino-5,6,7,8-tetrahydropyrazolo[5,1-b]...)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCCc3c(N)n2n1
Show InChI InChI=1S/C24H30N6O3S/c1-15-10-11-19(28-34(2,32)33)17(13-15)24(31)29-12-6-5-9-21(29)20-14-22-26-18-8-4-3-7-16(18)23(25)30(22)27-20/h10-11,13-14,21,28H,3-9,12,25H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 19.5n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301507
PNG
(US10131673, Compound P34)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCOCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C27H34N6O5S/c1-18-6-7-22(30-39(2,35)36)19(15-18)27(34)32-9-4-3-5-24(32)23-16-25-28-21-8-12-38-17-20(21)26(33(25)29-23)31-10-13-37-14-11-31/h6-7,15-16,24,30H,3-5,8-14,17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 20.9n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301493
PNG
(US10131673, Compound P20)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C27H34N6O4S/c1-18-9-10-22(30-38(2,35)36)20(16-18)27(34)32-11-4-3-8-24(32)23-17-25-28-21-7-5-6-19(21)26(33(25)29-23)31-12-14-37-15-13-31/h9-10,16-17,24,30H,3-8,11-15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 22.9n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301487
PNG
(US10131673, Compound P14)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCCc3c(O)n2n1
Show InChI InChI=1S/C24H29N5O4S/c1-15-10-11-19(27-34(2,32)33)17(13-15)23(30)28-12-6-5-9-21(28)20-14-22-25-18-8-4-3-7-16(18)24(31)29(22)26-20/h10-11,13-14,21,27,31H,3-9,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 40.7n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301505
PNG
(N-(5-methyl-4-(2-(9-morpholino-6,8-dihydro-5H-pyra...)
Show SMILES Cc1cccc2nc(NS(C)(=O)=O)nc(N3CCCCC3c3cc4nc5COCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C28H34N8O4S/c1-18-6-5-7-20-25(18)26(31-28(30-20)33-41(2,37)38)35-10-4-3-8-23(35)21-16-24-29-22-17-40-13-9-19(22)27(36(24)32-21)34-11-14-39-15-12-34/h5-7,16,23H,3-4,8-15,17H2,1-2H3,(H,30,31,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 55n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301496
PNG
(N-(4-methyl-2-(2-(10-morpholino-6,7,8,9-tetrahydro...)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C29H38N6O4S/c1-20-11-12-24(32-40(2,37)38)22(18-20)29(36)34-13-7-6-10-26(34)25-19-27-30-23-9-5-3-4-8-21(23)28(35(27)31-25)33-14-16-39-17-15-33/h11-12,18-19,26,32H,3-10,13-17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 66.1n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301485
PNG
(US10131673, Compound P12)
Show SMILES COc1cccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C28H33N7O2/c1-36-24-11-6-9-21-26(24)27(30-18-29-21)34-12-5-4-10-23(34)22-17-25-31-20-8-3-2-7-19(20)28(35(25)32-22)33-13-15-37-16-14-33/h6,9,11,17-18,23H,2-5,7-8,10,12-16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 75.9n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301490
PNG
(N-(4-methyl-2-(2-(5,6,7,8-tetrahydropyrazolo[5,1-b...)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3CCCCc3cn2n1
Show InChI InChI=1S/C24H29N5O3S/c1-16-10-11-20(27-33(2,31)32)18(13-16)24(30)28-12-6-5-9-22(28)21-14-23-25-19-8-4-3-7-17(19)15-29(23)26-21/h10-11,13-15,22,27H,3-9,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 97.7n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294979
PNG
(US10112911, Example 1.44)
Show SMILES CCC1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C23H25N7/c1-3-18-15-29(22-14-25-20-10-6-7-11-21(20)27-22)12-13-30(18)23(26-16-24)28-19-9-5-4-8-17(19)2/h4-11,14,18H,3,12-13,15H2,1-2H3,(H,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 120n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294954
PNG
(US10112911, Example 1.19)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1Cl)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C23H24ClN7/c1-16(2)21-14-30(22-13-26-19-9-5-6-10-20(19)28-22)11-12-31(21)23(27-15-25)29-18-8-4-3-7-17(18)24/h3-10,13,16,21H,11-12,14H2,1-2H3,(H,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 150n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301480
PNG
(BDBM301481 | US10131673, Compound P7)
Show SMILES Cc1cccc2nc(NS(C)(=O)=O)nc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C29H36N8O3S/c1-19-8-7-11-22-26(19)27(32-29(31-22)34-41(2,38)39)36-13-6-5-12-24(36)23-18-25-30-21-10-4-3-9-20(21)28(37(25)33-23)35-14-16-40-17-15-35/h7-8,11,18,24H,3-6,9-10,12-17H2,1-2H3,(H,31,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 162n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301511
PNG
(US10131673, Compound P38)
Show SMILES Cc1cccc2ncnc(N3CCCC[C@H]3c3cc4nc5CCCCc5c(C)n4n3)c12
Show InChI InChI=1S/C25H28N6/c1-16-8-7-11-20-24(16)25(27-15-26-20)30-13-6-5-12-22(30)21-14-23-28-19-10-4-3-9-18(19)17(2)31(23)29-21/h7-8,11,14-15,22H,3-6,9-10,12-13H2,1-2H3/t22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 162n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301477
PNG
(US10131673, Compound P4)
Show SMILES Cc1ccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c2c1
Show InChI InChI=1S/C28H33N7O/c1-19-9-10-22-21(16-19)27(30-18-29-22)34-11-5-4-8-25(34)24-17-26-31-23-7-3-2-6-20(23)28(35(26)32-24)33-12-14-36-15-13-33/h9-10,16-18,25H,2-8,11-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 166n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294948
PNG
(US10112911, Example 1.13)
Show SMILES CC(C)[C@H]1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C24H27N7/c1-17(2)22-15-30(23-14-26-20-10-6-7-11-21(20)28-23)12-13-31(22)24(27-16-25)29-19-9-5-4-8-18(19)3/h4-11,14,17,22H,12-13,15H2,1-3H3,(H,27,29)/t22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 200n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301513
PNG
(US10131673, Compound P40)
Show SMILES Cc1cccc2ncnc(N3CCCC[C@H]3c3cc4nc(C)c5CCCCc5n4n3)c12
Show InChI InChI=1S/C25H28N6/c1-16-8-7-10-19-24(16)25(27-15-26-19)30-13-6-5-12-22(30)20-14-23-28-17(2)18-9-3-4-11-21(18)31(23)29-20/h7-8,10,14-15,22H,3-6,9,11-13H2,1-2H3/t22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 200n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301514
PNG
(N-(5-methyl-4-(2-(8-morpholino-6,7-dihydro-5H-cycl...)
Show SMILES Cc1cccc2nc(NS(C)(=O)=O)nc(N3CCCCC3c3cc4nc5CCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C28H34N8O3S/c1-18-7-5-10-21-25(18)26(31-28(30-21)33-40(2,37)38)35-12-4-3-11-23(35)22-17-24-29-20-9-6-8-19(20)27(36(24)32-22)34-13-15-39-16-14-34/h5,7,10,17,23H,3-4,6,8-9,11-16H2,1-2H3,(H,30,31,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 229n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294859
PNG
(US10112911, Example 1.3)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C24H27N7/c1-17(2)22-15-30(23-14-26-20-10-6-7-11-21(20)28-23)12-13-31(22)24(27-16-25)29-19-9-5-4-8-18(19)3/h4-11,14,17,22H,12-13,15H2,1-3H3,(H,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294989
PNG
(US10112911, Example 1.54)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2cc(F)ccc2n1
Show InChI InChI=1S/C24H26FN7/c1-16(2)22-14-31(23-13-27-21-12-18(25)8-9-20(21)29-23)10-11-32(22)24(28-15-26)30-19-7-5-4-6-17(19)3/h4-9,12-13,16,22H,10-11,14H2,1-3H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 260n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301478
PNG
(US10131673, Compound P5)
Show SMILES Cc1cccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C28H33N7O/c1-19-7-6-10-22-26(19)27(30-18-29-22)34-12-5-4-11-24(34)23-17-25-31-21-9-3-2-8-20(21)28(35(25)32-23)33-13-15-36-16-14-33/h6-7,10,17-18,24H,2-5,8-9,11-16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 275n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301495
PNG
(2-(1-(5-methylquinazolin-4-yl)piperidin-2-yl)-8-(p...)
Show SMILES Cc1cccc2ncnc(N3CCCCC3c3cc4nc5CCCc5c(N5CCCC5)n4n3)c12
Show InChI InChI=1S/C27H31N7/c1-18-8-6-11-21-25(18)26(29-17-28-21)33-15-3-2-12-23(33)22-16-24-30-20-10-7-9-19(20)27(34(24)31-22)32-13-4-5-14-32/h6,8,11,16-17,23H,2-5,7,9-10,12-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 282n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301503
PNG
(2-(1-(5-methylquinazolin-4-yl)piperidin-2-yl)-9-mo...)
Show SMILES Cc1cccc2ncnc(N3CCCCC3c3cc4nc5CCOCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C27H31N7O2/c1-18-5-4-6-21-25(18)26(29-17-28-21)33-9-3-2-7-23(33)22-15-24-30-20-8-12-36-16-19(20)27(34(24)31-22)32-10-13-35-14-11-32/h4-6,15,17,23H,2-3,7-14,16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 282n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294991
PNG
(US10112911, Example 1.57)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2cc(ccc2n1)C(F)(F)F
Show InChI InChI=1S/C25H26F3N7/c1-16(2)22-14-34(23-13-30-21-12-18(25(26,27)28)8-9-20(21)32-23)10-11-35(22)24(31-15-29)33-19-7-5-4-6-17(19)3/h4-9,12-13,16,22H,10-11,14H2,1-3H3,(H,31,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 290n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294968
PNG
(US10112911, Example 1.33)
Show SMILES CC(C)C1CN(CCN1\C(Nc1c(C)cccc1F)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C24H26FN7/c1-16(2)21-14-31(22-13-27-19-9-4-5-10-20(19)29-22)11-12-32(21)24(28-15-26)30-23-17(3)7-6-8-18(23)25/h4-10,13,16,21H,11-12,14H2,1-3H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 300n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301501
PNG
(US10131673, Compound P28)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3COCCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C27H34N6O5S/c1-18-6-7-21(30-39(2,35)36)20(15-18)27(34)32-9-4-3-5-24(32)22-16-25-28-23-17-38-12-8-19(23)26(33(25)29-22)31-10-13-37-14-11-31/h6-7,15-16,24,30H,3-5,8-14,17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 355n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM295001
PNG
(US10112911, Example 1.67)
Show SMILES CC(C)[C@H]1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2cc(F)ccc2n1
Show InChI InChI=1S/C24H26FN7/c1-16(2)22-14-31(23-13-27-21-12-18(25)8-9-20(21)29-23)10-11-32(22)24(28-15-26)30-19-7-5-4-6-17(19)3/h4-9,12-13,16,22H,10-11,14H2,1-3H3,(H,28,30)/t22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 360n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294957
PNG
(US10112911, Example 1.22)
Show SMILES CC(C)C1CN(CCN1\C(Nc1cccc(C)c1)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C24H27N7/c1-17(2)22-15-30(23-14-26-20-9-4-5-10-21(20)29-23)11-12-31(22)24(27-16-25)28-19-8-6-7-18(3)13-19/h4-10,13-14,17,22H,11-12,15H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 400n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294972
PNG
(US10112911, Example 1.37)
Show SMILES CC(C)CC1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C25H29N7/c1-18(2)14-20-16-31(24-15-27-22-10-6-7-11-23(22)29-24)12-13-32(20)25(28-17-26)30-21-9-5-4-8-19(21)3/h4-11,15,18,20H,12-14,16H2,1-3H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 400n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301489
PNG
(N,N-dimethyl-2-(1-(5-methylquinazolin-4-yl)piperid...)
Show SMILES CN(C)c1c2CCCCc2nc2cc(nn12)C1CCCCN1C(=O)c1c(C)cccc1NS(C)(=O)=O
Show InChI InChI=1S/C26H34N6O3S/c1-17-10-9-13-20(29-36(4,34)35)24(17)26(33)31-15-8-7-14-22(31)21-16-23-27-19-12-6-5-11-18(19)25(30(2)3)32(23)28-21/h9-10,13,16,22,29H,5-8,11-12,14-15H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 407n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294945
PNG
(US10112911, Example 1.10)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1nc2ccccc2c(=O)[nH]1
Show InChI InChI=1S/C24H27N7O/c1-16(2)21-14-30(24-28-20-11-7-5-9-18(20)22(32)29-24)12-13-31(21)23(26-15-25)27-19-10-6-4-8-17(19)3/h4-11,16,21H,12-14H2,1-3H3,(H,26,27)(H,28,29,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 430n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294943
PNG
(US10112911, Example 1.8)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1ncnc2ccccc12
Show InChI InChI=1S/C24H27N7/c1-17(2)22-14-30(23-19-9-5-7-11-21(19)27-16-28-23)12-13-31(22)24(26-15-25)29-20-10-6-4-8-18(20)3/h4-11,16-17,22H,12-14H2,1-3H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 450n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301498
PNG
(US10131673, Compound P25)
Show SMILES Cc1ccc(NS(C)(=O)=O)c(c1)C(=O)N1CCCCC1c1cc2nc3COCc3c(N3CCOCC3)n2n1
Show InChI InChI=1S/C26H32N6O5S/c1-17-6-7-20(29-38(2,34)35)18(13-17)26(33)31-8-4-3-5-23(31)21-14-24-27-22-16-37-15-19(22)25(32(24)28-21)30-9-11-36-12-10-30/h6-7,13-14,23,29H,3-5,8-12,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 468n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294952
PNG
(US10112911, Example 1.17)
Show SMILES CC(C)C1CN(CCN1\C(Nc1c(C)cccc1C)=N/C#N)c1cnc2ccccc2n1
Show InChI InChI=1S/C25H29N7/c1-17(2)22-15-31(23-14-27-20-10-5-6-11-21(20)29-23)12-13-32(22)25(28-16-26)30-24-18(3)8-7-9-19(24)4/h5-11,14,17,22H,12-13,15H2,1-4H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 540n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301484
PNG
(US10131673, Compound P11)
Show SMILES FC(F)(F)c1cccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C28H30F3N7O/c29-28(30,31)19-7-5-9-21-25(19)26(33-17-32-21)37-11-4-3-10-23(37)22-16-24-34-20-8-2-1-6-18(20)27(38(24)35-22)36-12-14-39-15-13-36/h5,7,9,16-17,23H,1-4,6,8,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 676n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294986
PNG
(US10112911, Example 1.51)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1cnc2cc(F)c(F)cc2n1
Show InChI InChI=1S/C24H25F2N7/c1-15(2)22-13-32(23-12-28-20-10-17(25)18(26)11-21(20)30-23)8-9-33(22)24(29-14-27)31-19-7-5-4-6-16(19)3/h4-7,10-12,15,22H,8-9,13H2,1-3H3,(H,29,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 690n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301494
PNG
(4-(2-(1-(5-methylquinazolin-4-yl)piperidin-2-yl)-6...)
Show SMILES Cc1cccc2ncnc(N3CCCCC3c3cc4nc5CCCc5c(N5CCOCC5)n4n3)c12
Show InChI InChI=1S/C27H31N7O/c1-18-6-4-9-21-25(18)26(29-17-28-21)33-11-3-2-10-23(33)22-16-24-30-20-8-5-7-19(20)27(34(24)31-22)32-12-14-35-15-13-32/h4,6,9,16-17,23H,2-3,5,7-8,10-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 708n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301486
PNG
(US10131673, Compound P13)
Show SMILES CCc1ccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(N5CCOCC5)n4n3)c2c1C
Show InChI InChI=1S/C30H37N7O/c1-3-21-11-12-24-28(20(21)2)29(32-19-31-24)36-13-7-6-10-26(36)25-18-27-33-23-9-5-4-8-22(23)30(37(27)34-25)35-14-16-38-17-15-35/h11-12,18-19,26H,3-10,13-17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 724n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301508
PNG
(9-methyl-2-(1-(5-methylquinazolin-4-yl)piperidin-2...)
Show SMILES Cc1cccc2ncnc(N3CCCCC3c3cc4nc5CCCCc5c(C)n4n3)c12
Show InChI InChI=1S/C25H28N6/c1-16-8-7-11-20-24(16)25(27-15-26-20)30-13-6-5-12-22(30)21-14-23-28-19-10-4-3-9-18(19)17(2)31(23)29-21/h7-8,11,14-15,22H,3-6,9-10,12-13H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 776n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294913
PNG
(US10112911, Example 1.5)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1nc2cccc(Cl)c2o1
Show InChI InChI=1S/C23H25ClN6O/c1-15(2)20-13-29(23-28-19-10-6-8-17(24)21(19)31-23)11-12-30(20)22(26-14-25)27-18-9-5-4-7-16(18)3/h4-10,15,20H,11-13H2,1-3H3,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 810n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM301506
PNG
(2-(1-(2-ethoxy-5-methylquinazolin-4-yl)piperidin-2...)
Show SMILES CCOc1nc(N2CCCCC2c2cc3nc4CCOCc4c(N4CCOCC4)n3n2)c2c(C)cccc2n1
Show InChI InChI=1S/C29H35N7O3/c1-3-39-29-31-22-8-6-7-19(2)26(22)27(32-29)35-11-5-4-9-24(35)23-17-25-30-21-10-14-38-18-20(21)28(36(25)33-23)34-12-15-37-16-13-34/h6-8,17,24H,3-5,9-16,18H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 813n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
Black 384-well clear-bottom microtiter plates (Corning, Amsterdam, The Netherlands) were filled via acoustic drop ejection using the echo liquid hand...


US Patent US10131673 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294942
PNG
(US10112911, Example 1.7)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1nc2cc(C)ccc2o1
Show InChI InChI=1S/C24H28N6O/c1-16(2)21-14-29(24-28-20-13-17(3)9-10-22(20)31-24)11-12-30(21)23(26-15-25)27-19-8-6-5-7-18(19)4/h5-10,13,16,21H,11-12,14H2,1-4H3,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 830n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM294857
PNG
(US10112911, Example 1.1)
Show SMILES CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1nccnc1C#N
Show InChI InChI=1S/C21H24N8/c1-15(2)19-13-28(20-18(12-22)24-8-9-25-20)10-11-29(19)21(26-14-23)27-17-7-5-4-6-16(17)3/h4-9,15,19H,10-11,13H2,1-3H3,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 890n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
A cytopathetic effect (CPE) protection assay was performed to determine the ability of a compound to protect the cells from viral infection and thus ...


US Patent US10112911 (2018)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 117 total )  |  Next  |  Last  >>
Jump to: