Affinity DataIC50: 0.00380nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Antagonist activity at recombinant human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta arrestin2 recruitment p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Binding affinity against Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Binding affinity for human cloned Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Antagonist activity at dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM IC50: 1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
Affinity DataKi: 3nM IC50: 1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM IC50: 1.20nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonistic activity at D3 receptor (unknown origin) expressed in cell membranes assessed as inhibition of quinpirole-induced response after 40 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]methylspiperone from human recombinant Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair