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Found 26 of ic50 data for polymerid = 49000313
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50386813(CHEMBL2047726)
Affinity DataIC50:  40.7nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50386813(CHEMBL2047726)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438747(CHEMBL2414787)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434732(CHEMBL2385364)
Affinity DataIC50:  850nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438746(CHEMBL2414771)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434737(CHEMBL2385359)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434738(CHEMBL2385358)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434735(CHEMBL2385361)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434742(CHEMBL2385371)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438746(CHEMBL2414771)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434734(CHEMBL2385362)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434741(CHEMBL2385372)
Affinity DataIC50:  4.85E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434747(CHEMBL2385366)
Affinity DataIC50:  8.37E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434731(CHEMBL2385365)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434740(CHEMBL2385356)
Affinity DataIC50:  9.84E+3nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434736(CHEMBL2385360)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434733(CHEMBL2385363)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434739(CHEMBL2385357)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434746(CHEMBL2385367)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434745(CHEMBL2385368)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434744(CHEMBL2385369)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50434743(CHEMBL2385370)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438747(CHEMBL2414787)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50444089(CHEMBL3092995)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells by FDSS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50444089(CHEMBL3092995)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of rat Cav2.2-mediated calcium flux expressed in HEK cells at 0.07 Hz by whole-cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50259131(CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed