Affinity DataEC50: 2nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Compound was tested in vitro for depolarizing response on the rat superior cervical ganglion(mediated by Muscarinic M1 receptor)More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Compound was tested in vitro for depolarizing response on the rat superior cervical ganglion(mediated by Muscarinic M1 receptor)More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Compound was tested in vitro for depolarizing response on the rat superior cervical ganglion(mediated by Muscarinic M1 receptor)More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at rat muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Partial agonist activity at rat muscarinic M1 receptor expressed in CHO cells calcium responseMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Partial agonist activity at rat muscarinic M1 receptor expressed in CHO cells calcium responseMore data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 95nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 97nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 101nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Compound was tested in vitro for depolarizing response on the rat superior cervical ganglion(mediated by muscarinic acetylcholine receptor M1)More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Partial agonist activity at rat muscarinic M1 receptor expressed in CHO cells calcium responseMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at rat muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 118nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at rat muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 137nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at rat muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 152nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
Affinity DataEC50: 154nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
Affinity DataEC50: 154nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
Affinity DataEC50: 163nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIP...More data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
Affinity DataEC50: 182nMAssay Description:Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...More data for this Ligand-Target Pair
