Affinity DataKi: 0.00780nMAssay Description:Displacement of [3H]-NMS from human recombinant M4 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
Affinity DataKi: 0.115nMAssay Description:Displacement of [3H]-NMS from human recombinant M4 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor(PORCINE)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataKi: 0.320nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Antagonist activity at muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(bovine)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataKi: 0.382nMAssay Description:Displacement of [3H]-NMS from human recombinant M4 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.417nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
Affinity DataKi: 0.447nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor stably expressed in CHO-K9 cells by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.468nMAssay Description:Displacement of [3H]NMS from human muscarinic acetylcholine receptor M4 expressed in CHOK9 cells after 3 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M2) in guinea pig left atriaMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(bovine)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic M4 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.661nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition...More data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.724nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition...More data for this Ligand-Target Pair
Affinity DataKi: 0.741nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition...More data for this Ligand-Target Pair
Affinity DataKi: 0.776nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition...More data for this Ligand-Target Pair
Affinity DataKi: 0.813nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]4-DAMP from human recombinant M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.912nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K1 cell membranes incubated for 2 hrs by scintillation countin...More data for this Ligand-Target Pair