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Compile Data Set for Download or QSAR

Found 2 hits of kd for Ionotropic glutamate receptor NMDA 1/2D
having polymerids = 49000630,49000814 and
complexids = 50000424,50004363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50414372
PNG
(CHEMBL2145458)
Show SMILES NC[C@@H]1NC(=O)CNC1=O
Show InChI InChI=1S/C5H9N3O2/c6-1-3-5(10)7-2-4(9)8-3/h3H,1-2,6H2,(H,7,10)(H,8,9)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.00E+4n/an/an/an/an/a



University of Berne

Curated by ChEMBL


Assay Description
Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response


Bioorg Med Chem Lett 19: 3832-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.021
BindingDB Entry DOI: 10.7270/Q2Z0386F
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))
BDBM50004840
PNG
(Amino-(4-phosphonomethyl-phenyl)-acetic acid | CHE...)
Show SMILES NC(C(O)=O)c1ccc(CP(O)(O)=O)cc1
Show InChI InChI=1S/C9H12NO5P/c10-8(9(11)12)7-3-1-6(2-4-7)5-16(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 3.00E+3n/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Dissociation constant of the compound against N-methyl-D-aspartate glutamate receptor using [3H]-CPP binding was determined


Bioorg Med Chem Lett 10: 1241-4 (2000)


Article DOI: 10.1016/s0960-894x(00)00197-9
BindingDB Entry DOI: 10.7270/Q26972SC
More data for this
Ligand-Target Pair