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Compile Data Set for Download or QSAR

Found 2 hits of kd for Phosphodiesterase 4
having polymerids = 49000917 and
complexids = 50000732,50006150,50006298   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50228245
PNG
(CHEMBL34945 | LY-186126)
Show SMILES CC1CC(=O)NN=C1c1ccc2N(C)C(=O)C(C)(C)c2c1
Show InChI InChI=1S/C16H19N3O2/c1-9-7-13(20)17-18-14(9)10-5-6-12-11(8-10)16(2,3)15(21)19(12)4/h5-6,8-9H,7H2,1-4H3,(H,17,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 4.10n/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for Phosphodiesterase 4 of canine myocardial vesicles


J Med Chem 32: 1476-80 (1989)


Article DOI: 10.1021/jm00127a014
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50228245
PNG
(CHEMBL34945 | LY-186126)
Show SMILES CC1CC(=O)NN=C1c1ccc2N(C)C(=O)C(C)(C)c2c1
Show InChI InChI=1S/C16H19N3O2/c1-9-7-13(20)17-18-14(9)10-5-6-12-11(8-10)16(2,3)15(21)19(12)4/h5-6,8-9H,7H2,1-4H3,(H,17,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.90n/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for sarcoplasmic reticulum phosphodiesterase 4 of canine ventricle


J Med Chem 32: 1476-80 (1989)


Article DOI: 10.1021/jm00127a014
More data for this
Ligand-Target Pair