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Compile Data Set for Download or QSAR

Found 141 hits of kd data for polymerid = 49001019,50001327,6827   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SSTR1


(RAT)
BDBM50423465
PNG
(ERGOLINE)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H30BrN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m1/s1
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n/an/an/a 0.204n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423299
PNG
(CHEMBL401290)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(C)(=O)=O)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C25H30N6O4S2/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)35-37(2,33)34)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-36-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1
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n/an/an/a 0.214n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423475
PNG
(CHEMBL252032)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C25H26ClN7OS/c1-31-13-14(11-16-15-3-2-4-18-22(15)17(12-20(16)31)23(26)27-18)25(34)33-9-7-32(8-10-33)21-6-5-19-24(28-21)30-35-29-19/h2-6,14,16,20,27H,7-13H2,1H3/t14-,16-,20-/m1/s1
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n/an/an/a 0.240n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423480
PNG
(CHEMBL254505)
Show SMILES CCn1c(cccc1=O)N1CCN(CC1)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c(Br)[nH]c4cccc2c34)N(C)C1
Show InChI InChI=1S/C27H32BrN5O2/c1-3-33-23(8-5-9-24(33)34)31-10-12-32(13-11-31)27(35)17-14-19-18-6-4-7-21-25(18)20(26(28)29-21)15-22(19)30(2)16-17/h4-9,17,19,22,29H,3,10-16H2,1-2H3/t17-,19-,22-/m1/s1
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n/an/an/a 0.282n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423478
PNG
(CHEMBL252033)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C25H26BrN7OS/c1-31-13-14(11-16-15-3-2-4-18-22(15)17(12-20(16)31)23(26)27-18)25(34)33-9-7-32(8-10-33)21-6-5-19-24(28-21)30-35-29-19/h2-6,14,16,20,27H,7-13H2,1H3/t14-,16-,20-/m1/s1
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n/an/an/a 0.372n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423462
PNG
(CHEMBL251835)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Show InChI InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 0.372n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423472
PNG
(CHEMBL401309)
Show SMILES CCn1c(cccc1=O)N1CCN(CC1)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c(Cl)[nH]c4cccc2c34)N(C)C1
Show InChI InChI=1S/C27H32ClN5O2/c1-3-33-23(8-5-9-24(33)34)31-10-12-32(13-11-31)27(35)17-14-19-18-6-4-7-21-25(18)20(26(28)29-21)15-22(19)30(2)16-17/h4-9,17,19,22,29H,3,10-16H2,1-2H3/t17-,19-,22-/m1/s1
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n/an/an/a 0.380n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423481
PNG
(CHEMBL254499)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H30ClN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m1/s1
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n/an/an/a 0.389n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423483
PNG
(CHEMBL398526)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Show InChI InChI=1S/C26H27ClN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 0.389n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423314
PNG
(CHEMBL251754)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)C(F)(F)F)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C25H27F3N6O4S2/c1-32-14-17(24(35)34-9-7-33(8-10-34)22-6-5-19-23(29-22)31-39-30-19)11-16-12-18-15(13-20(16)32)3-2-4-21(18)38-40(36,37)25(26,27)28/h2-6,16-17,20H,7-14H2,1H3/t16-,17-,20-/m1/s1
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n/an/an/a 0.398n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423317
PNG
(CHEMBL440236)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(C)(=O)=O)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C26H32N4O6S/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)36-37(2,34)35)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 0.407n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423477
PNG
(CHEMBL252618)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C26H27BrF2N4O/c1-31-14-15(11-18-17-3-2-4-22-24(17)19(13-23(18)31)25(27)30-22)26(34)33-9-7-32(8-10-33)16-5-6-20(28)21(29)12-16/h2-6,12,15,18,23,30H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 0.490n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423308
PNG
(CHEMBL251753)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)c1ccc(C)cc1)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C31H34N6O4S2/c1-20-6-8-24(9-7-20)43(39,40)41-28-5-3-4-21-18-27-22(17-25(21)28)16-23(19-35(27)2)31(38)37-14-12-36(13-15-37)29-11-10-26-30(32-29)34-42-33-26/h3-11,22-23,27H,12-19H2,1-2H3/t22-,23-,27-/m1/s1
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n/an/an/a 0.575n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423467
PNG
(CHEMBL252428)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C26H27ClF2N4O/c1-31-14-15(11-18-17-3-2-4-22-24(17)19(13-23(18)31)25(27)30-22)26(34)33-9-7-32(8-10-33)16-5-6-20(28)21(29)12-16/h2-6,12,15,18,23,30H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 0.603n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423297
PNG
(CHEMBL251541 | Obelin)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 0.708n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423297
PNG
(CHEMBL251541 | Obelin)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 0.708n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423471
PNG
(CHEMBL254288)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H31N5O2/c1-28-16-18(13-20-19-5-3-6-21-25(19)17(15-27-21)14-22(20)28)26(33)31-11-9-30(10-12-31)23-7-4-8-24(32)29(23)2/h3-8,15,18,20,22,27H,9-14,16H2,1-2H3/t18-,20-,22-/m1/s1
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n/an/an/a 0.759n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423301
PNG
(CHEMBL251542)
Show SMILES CC(C)Oc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C28H36N4O4/c1-19(2)36-27-6-4-5-20-17-26-21(16-25(20)27)15-22(18-29(26)3)28(33)31-13-11-30(12-14-31)23-7-9-24(10-8-23)32(34)35/h4-10,19,21-22,26H,11-18H2,1-3H3/t21-,22-,26-/m1/s1
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n/an/an/a 0.813n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423294
PNG
(CHEMBL248908)
Show SMILES COc1ccc(C=O)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12
Show InChI InChI=1S/C26H30N6O3S/c1-30-14-18(11-17-12-20-19(13-22(17)30)16(15-33)3-5-23(20)35-2)26(34)32-9-7-31(8-10-32)24-6-4-21-25(27-24)29-36-28-21/h3-6,15,17-18,22H,7-14H2,1-2H3/t17-,18-,22-/m1/s1
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n/an/an/a 0.832n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423463
PNG
(CHEMBL254287)
Show SMILES CCN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C27H29BrF2N4O/c1-2-32-15-16(12-19-18-4-3-5-23-25(18)20(14-24(19)32)26(28)31-23)27(35)34-10-8-33(9-11-34)17-6-7-21(29)22(30)13-17/h3-7,13,16,19,24,31H,2,8-12,14-15H2,1H3/t16-,19-,24-/m1/s1
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n/an/an/a 0.977n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423476
PNG
(CHEMBL251836)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C25H27N7OS/c1-30-14-16(11-18-17-3-2-4-19-23(17)15(13-26-19)12-21(18)30)25(33)32-9-7-31(8-10-32)22-6-5-20-24(27-22)29-34-28-20/h2-6,13,16,18,21,26H,7-12,14H2,1H3/t16-,18-,21-/m1/s1
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n/an/an/a 1n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50423462
PNG
(CHEMBL251835)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Show InChI InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst1 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423312
PNG
(CHEMBL249113)
Show SMILES COc1cccc2C[C@H]3NC[C@@H](C[C@@H]3Cc12)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C25H30N4O4/c1-33-24-4-2-3-17-15-23-18(14-22(17)24)13-19(16-26-23)25(30)28-11-9-27(10-12-28)20-5-7-21(8-6-20)29(31)32/h2-8,18-19,23,26H,9-16H2,1H3/t18-,19-,23-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423303
PNG
(CHEMBL248907)
Show SMILES COc1ccc(Br)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12
Show InChI InChI=1S/C25H29BrN6O2S/c1-30-14-16(11-15-12-18-17(13-21(15)30)19(26)3-5-22(18)34-2)25(33)32-9-7-31(8-10-32)23-6-4-20-24(27-23)29-35-28-20/h3-6,15-16,21H,7-14H2,1-2H3/t15-,16-,21-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423302
PNG
(CHEMBL248715)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12
Show InChI InChI=1S/C25H30N6O2S/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)33-2)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-34-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423307
PNG
(CHEMBL399464)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OCc1ccccc1)C(=O)N1CCN(CC1)c1ccc2nsnc2n1
Show InChI InChI=1S/C31H34N6O2S/c1-35-19-24(31(38)37-14-12-36(13-15-37)29-11-10-26-30(32-29)34-40-33-26)16-23-17-25-22(18-27(23)35)8-5-9-28(25)39-20-21-6-3-2-4-7-21/h2-11,23-24,27H,12-20H2,1H3/t23-,24-,27-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423302
PNG
(CHEMBL248715)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nsnc4n3)Cc12
Show InChI InChI=1S/C25H30N6O2S/c1-29-15-18(12-17-13-19-16(14-21(17)29)4-3-5-22(19)33-2)25(32)31-10-8-30(9-11-31)23-7-6-20-24(26-23)28-34-27-20/h3-7,17-18,21H,8-15H2,1-2H3/t17-,18-,21-/m1/s1
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n/an/an/a 1.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423361
PNG
(CHEMBL398681)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccccc3[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-21-18(16-24(19)27)6-5-9-25(21)34-2)26(31)29-12-10-28(11-13-29)22-7-3-4-8-23(22)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 1.30n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423474
PNG
(CHEMBL398712)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C26H28ClN5O3/c1-29-15-16(13-20-19-3-2-4-22-24(19)21(14-23(20)29)25(27)28-22)26(33)31-11-9-30(10-12-31)17-5-7-18(8-6-17)32(34)35/h2-8,16,20,23,28H,9-15H2,1H3/t16-,20-,23-/m1/s1
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n/an/an/a 1.30n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423352
PNG
(CHEMBL250498)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc(c3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(13-19-14-23-18(15-24(19)27)5-3-8-25(23)34-2)26(31)29-11-9-28(10-12-29)21-6-4-7-22(16-21)30(32)33/h3-8,16,19-20,24H,9-15,17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 1.30n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423479
PNG
(CHEMBL252229)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C26H28BrN5O3/c1-29-15-16(13-20-19-3-2-4-22-24(19)21(14-23(20)29)25(27)28-22)26(33)31-11-9-30(10-12-31)17-5-7-18(8-6-17)32(34)35/h2-8,16,20,23,28H,9-15H2,1H3/t16-,20-,23-/m1/s1
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n/an/an/a 1.40n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423315
PNG
(CHEMBL399658)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)C(F)(F)F)C(=O)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C25H29F3N4O4S/c1-30-16-19(24(33)32-11-9-31(10-12-32)23-7-2-3-8-29-23)13-18-14-20-17(15-21(18)30)5-4-6-22(20)36-37(34,35)25(26,27)28/h2-8,18-19,21H,9-16H2,1H3/t18-,19-,21-/m1/s1
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n/an/an/a 1.40n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423309
PNG
(CHEMBL399843)
Show SMILES CN1C[C@@H](C[C@@H]2Cc3c(C[C@@H]12)cccc3OS(=O)(=O)C(F)(F)F)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C26H29F3N4O6S/c1-30-16-19(25(34)32-11-9-31(10-12-32)20-5-7-21(8-6-20)33(35)36)13-18-14-22-17(15-23(18)30)3-2-4-24(22)39-40(37,38)26(27,28)29/h2-8,18-19,23H,9-16H2,1H3/t18-,19-,23-/m1/s1
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n/an/an/a 1.60n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50423465
PNG
(ERGOLINE)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H30BrN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m1/s1
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n/an/an/a 1.70n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst1 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423330
PNG
(CHEMBL250922)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc4nonc4c3)Cc12
Show InChI InChI=1S/C26H31N5O3/c1-29-16-19(12-18-13-21-17(14-24(18)29)4-3-5-25(21)33-2)26(32)31-10-8-30(9-11-31)20-6-7-22-23(15-20)28-34-27-22/h3-7,15,18-19,24H,8-14,16H2,1-2H3/t18-,19-,24-/m1/s1
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n/an/an/a 1.70n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423337
PNG
(CHEMBL400137)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3S(C)(=O)=O)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C27H34N4O6S/c1-28-17-20(13-19-14-22-18(15-24(19)28)5-4-6-25(22)37-2)27(32)30-11-9-29(10-12-30)23-8-7-21(31(33)34)16-26(23)38(3,35)36/h4-8,16,19-20,24H,9-15,17H2,1-3H3/t19-,20-,24-/m1/s1
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n/an/an/a 1.70n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423364
PNG
(CHEMBL249930)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccccc3C#N)Cc12
Show InChI InChI=1S/C27H32N4O2/c1-29-18-22(14-21-15-23-19(16-25(21)29)7-5-9-26(23)33-2)27(32)31-12-10-30(11-13-31)24-8-4-3-6-20(24)17-28/h3-9,21-22,25H,10-16,18H2,1-2H3/t21-,22-,25-/m1/s1
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n/an/an/a 2n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423470
PNG
(CHEMBL253879)
Show SMILES CSc1[nH]c2cccc3[C@H]4C[C@H](CN(C)[C@@H]4Cc1c23)C(=O)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C26H31N5OS/c1-29-16-17(26(32)31-12-10-30(11-13-31)23-8-3-4-9-27-23)14-19-18-6-5-7-21-24(18)20(15-22(19)29)25(28-21)33-2/h3-9,17,19,22,28H,10-16H2,1-2H3/t17-,19-,22-/m1/s1
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n/an/an/a 2.40n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423334
PNG
(CHEMBL400136)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc(F)c3C#N)Cc12
Show InChI InChI=1S/C27H31FN4O2/c1-30-17-20(13-19-14-21-18(15-25(19)30)5-3-8-26(21)34-2)27(33)32-11-9-31(10-12-32)24-7-4-6-23(28)22(24)16-29/h3-8,19-20,25H,9-15,17H2,1-2H3/t19-,20-,25-/m1/s1
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n/an/an/a 2.80n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423320
PNG
(CHEMBL251120)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4nsnc34)Cc12
Show InChI InChI=1S/C26H31N5O2S/c1-29-16-19(13-18-14-20-17(15-23(18)29)5-3-8-24(20)33-2)26(32)31-11-9-30(10-12-31)22-7-4-6-21-25(22)28-34-27-21/h3-8,18-19,23H,9-16H2,1-2H3/t18-,19-,23-/m1/s1
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n/an/an/a 2.80n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423340
PNG
(CHEMBL250304)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(F)c(F)c3)Cc12
Show InChI InChI=1S/C26H31F2N3O2/c1-29-16-19(12-18-13-21-17(14-24(18)29)4-3-5-25(21)33-2)26(32)31-10-8-30(9-11-31)20-6-7-22(27)23(28)15-20/h3-7,15,18-19,24H,8-14,16H2,1-2H3/t18-,19-,24-/m1/s1
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n/an/an/a 2.80n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423351
PNG
(CHEMBL250305)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3C#N)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C27H31N5O4/c1-29-17-21(12-19-14-23-18(15-25(19)29)4-3-5-26(23)36-2)27(33)31-10-8-30(9-11-31)24-7-6-22(32(34)35)13-20(24)16-28/h3-7,13,19,21,25H,8-12,14-15,17H2,1-2H3/t19-,21-,25-/m1/s1
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n/an/an/a 3.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423358
PNG
(CHEMBL249723)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc(F)c3)Cc12
Show InChI InChI=1S/C26H32FN3O2/c1-28-17-20(13-19-14-23-18(15-24(19)28)5-3-8-25(23)32-2)26(31)30-11-9-29(10-12-30)22-7-4-6-21(27)16-22/h3-8,16,19-20,24H,9-15,17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 3.30n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423321
PNG
(CHEMBL400907)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(F)cc3)Cc12
Show InChI InChI=1S/C26H32FN3O2/c1-28-17-20(14-19-15-23-18(16-24(19)28)4-3-5-25(23)32-2)26(31)30-12-10-29(11-13-30)22-8-6-21(27)7-9-22/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 3.40n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423311
PNG
(CHEMBL399267)
Show SMILES COc1ccc(Cl)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H31ClN4O4/c1-28-16-18(13-17-14-22-21(15-24(17)28)23(27)7-8-25(22)35-2)26(32)30-11-9-29(10-12-30)19-3-5-20(6-4-19)31(33)34/h3-8,17-18,24H,9-16H2,1-2H3/t17-,18-,24-/m1/s1
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n/an/an/a 3.60n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423335
PNG
(CHEMBL250921)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4nonc34)Cc12
Show InChI InChI=1S/C26H31N5O3/c1-29-16-19(13-18-14-20-17(15-23(18)29)5-3-8-24(20)33-2)26(32)31-11-9-30(10-12-31)22-7-4-6-21-25(22)28-34-27-21/h3-8,18-19,23H,9-16H2,1-2H3/t18-,19-,23-/m1/s1
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n/an/an/a 3.60n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423354
PNG
(CHEMBL440233)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cn3)C#N)Cc12
Show InChI InChI=1S/C26H31N5O2/c1-29-17-21(12-20-13-22-19(14-23(20)29)4-3-5-24(22)33-2)26(32)31-10-8-30(9-11-31)25-7-6-18(15-27)16-28-25/h3-7,16,20-21,23H,8-14,17H2,1-2H3/t20-,21-,23-/m1/s1
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n/an/an/a 3.60n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane


Bioorg Med Chem Lett 17: 3988-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.078
BindingDB Entry DOI: 10.7270/Q2SX6FHF
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423486
PNG
(CHEMBL252029)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C26H29N5O3/c1-28-16-18(13-22-21-3-2-4-23-25(21)17(15-27-23)14-24(22)28)26(32)30-11-9-29(10-12-30)19-5-7-20(8-6-19)31(33)34/h2-8,15,18,22,24,27H,9-14,16H2,1H3/t18-,22-,24-/m1/s1
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n/an/an/a 3.90n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423484
PNG
(CHEMBL401131)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C26H28Cl2N4O/c1-30-15-16(26(33)32-11-9-31(10-12-32)18-7-5-17(27)6-8-18)13-20-19-3-2-4-22-24(19)21(14-23(20)30)25(28)29-22/h2-8,16,20,23,29H,9-15H2,1H3/t16-,20-,23-/m1/s1
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n/an/an/a 4.20n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
SSTR1


(RAT)
BDBM50423490
PNG
(CHEMBL253438)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C25H28BrN5O/c1-29-15-16(25(32)31-11-9-30(10-12-31)22-7-2-3-8-27-22)13-18-17-5-4-6-20-23(17)19(14-21(18)29)24(26)28-20/h2-8,16,18,21,28H,9-15H2,1H3/t16-,18-,21-/m1/s1
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n/an/an/a 4.5n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Displacement of [125I]SRIF14 from sst1 receptor in rat cortex


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
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