BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits of ec50 data for polymerid = 49001019,6827   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50294254
PNG
((4R,7S,10S,13R,16S,19R)-19-((R)-2-amino-3-(4-hydro...)
Show SMILES CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc2ccc(O)cc2)N(C)C(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C64H75N11O11S2/c1-37(2)67-34-43-21-19-42(20-22-43)32-50-58(80)68-49(30-39-13-7-5-8-14-39)59(81)72-53(62(84)73-54(38(3)76)55(66)78)36-88-87-35-52(71-57(79)48(65)29-41-23-27-47(77)28-24-41)61(83)69-51(31-40-15-9-6-10-16-40)60(82)74-56(63(85)70-50)75(4)64(86)46-26-25-44-17-11-12-18-45(44)33-46/h5-28,33,37-38,48-54,56,67,76-77H,29-32,34-36,65H2,1-4H3,(H2,66,78)(H,68,80)(H,69,83)(H,70,85)(H,71,79)(H,72,81)(H,73,84)(H,74,82)/t38-,48-,49+,50+,51+,52+,53+,54+,56-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.370n/an/an/an/a



The Clayton Foundation Laboratories for Peptide Biology

Curated by ChEMBL


Assay Description
Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14


J Med Chem 52: 2733-46 (2009)


Article DOI: 10.1021/jm801314f
BindingDB Entry DOI: 10.7270/Q2CV4JPR
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50294255
PNG
((4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-31...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)c1c[nH]c2ccccc12)[C@@H](C)O
Show InChI InChI=1S/C75H102N18O19S2/c1-40(78)63(99)81-36-59(98)82-56-38-113-114-39-57(75(111)112)90-70(106)55(37-94)89-73(109)61(42(3)96)92-68(104)53(33-45-23-11-6-12-24-45)88-72(108)60(41(2)95)91-65(101)50(28-16-18-30-77)84-74(110)62(47-35-80-48-26-14-13-25-46(47)48)93-69(105)52(32-44-21-9-5-10-22-44)86-66(102)51(31-43-19-7-4-8-20-43)85-67(103)54(34-58(79)97)87-64(100)49(83-71(56)107)27-15-17-29-76/h4-14,19-26,35,40-42,49-57,60-62,80,94-96H,15-18,27-34,36-39,76-78H2,1-3H3,(H2,79,97)(H,81,99)(H,82,98)(H,83,107)(H,84,110)(H,85,103)(H,86,102)(H,87,100)(H,88,108)(H,89,109)(H,90,106)(H,91,101)(H,92,104)(H,93,105)(H,111,112)/t40-,41+,42+,49-,50-,51-,52-,53-,54-,55-,56-,57-,60-,61-,62-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.930n/an/an/an/a



The Clayton Foundation Laboratories for Peptide Biology

Curated by ChEMBL


Assay Description
Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14


J Med Chem 52: 2733-46 (2009)


Article DOI: 10.1021/jm801314f
BindingDB Entry DOI: 10.7270/Q2CV4JPR
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50294252
PNG
((4R,7S,10S,13R,16S,19R)-19-amino-N-((2S,3R)-1-amin...)
Show SMILES CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)N(C)C(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C55H66N10O9S2/c1-32(2)58-29-37-21-19-36(20-22-37)27-43-50(69)60-42(25-34-13-7-5-8-14-34)51(70)62-45(53(72)63-46(33(3)66)47(57)67)31-76-75-30-41(56)49(68)59-44(26-35-15-9-6-10-16-35)52(71)64-48(54(73)61-43)65(4)55(74)40-24-23-38-17-11-12-18-39(38)28-40/h5-24,28,32-33,41-46,48,58,66H,25-27,29-31,56H2,1-4H3,(H2,57,67)(H,59,68)(H,60,69)(H,61,73)(H,62,70)(H,63,72)(H,64,71)/t33-,41+,42+,43+,44+,45+,46+,48-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.90n/an/an/an/a



The Clayton Foundation Laboratories for Peptide Biology

Curated by ChEMBL


Assay Description
Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14


J Med Chem 52: 2733-46 (2009)


Article DOI: 10.1021/jm801314f
BindingDB Entry DOI: 10.7270/Q2CV4JPR
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50294231
PNG
((4R,7S,10S,13S,16S,19S,22R,25S,28S,31S,34R)-22-((1...)
Show SMILES CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC2=O)[C@@H](C)O)[C@@H](C)O)C(O)=O)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1
Show InChI InChI=1S/C83H105N15O17S2/c1-47(2)86-42-55-29-27-54(28-30-55)40-64-77(108)97-70(48(3)100)81(112)93-65(39-52-22-12-7-13-23-52)78(109)98-71(49(4)101)82(113)94-67(44-99)79(110)96-69(83(114)115)46-117-116-45-68(95-72(103)59(85)36-53-31-33-57(102)34-32-53)80(111)88-61(26-16-17-35-84)73(104)89-62(37-50-18-8-5-9-19-50)74(105)90-63(38-51-20-10-6-11-21-51)75(106)92-66(76(107)91-64)41-56-43-87-60-25-15-14-24-58(56)60/h5-15,18-25,27-34,43,47-49,59,61-71,86-87,99-102H,16-17,26,35-42,44-46,84-85H2,1-4H3,(H,88,111)(H,89,104)(H,90,105)(H,91,107)(H,92,106)(H,93,112)(H,94,113)(H,95,103)(H,96,110)(H,97,108)(H,98,109)(H,114,115)/t48-,49-,59+,61+,62+,63+,64+,65+,66-,67+,68+,69+,70+,71+/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 33n/an/an/an/a



The Clayton Foundation Laboratories for Peptide Biology

Curated by ChEMBL


Assay Description
Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14


J Med Chem 52: 2733-46 (2009)


Article DOI: 10.1021/jm801314f
BindingDB Entry DOI: 10.7270/Q2CV4JPR
More data for this
Ligand-Target Pair