Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for UniProtKB: A0A024R996
TargetCyclin-Y/Cyclin-dependent kinase 18(Homo sapiens)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  51.1nMAssay Description:Inhibition of human CDK18/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  66.3nMAssay Description:Inhibition of human CDK18/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50404389(CHEMBL5285499)
Affinity DataIC50: >1.20E+3nMAssay Description:Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparationsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: >1.20E+3nMAssay Description:Displacement of specifically bound [3H]naloxone from rat brain homogenate, in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM126500(US11591322, Compound NVP-2 | US8778951, 310)
Affinity DataIC50:  4.90E+3nMAssay Description:Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50539721(CHEMBL4635959)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CDK18 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 18(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human cyclinY/CDK18 T166M mutant using YRRAAVPPSPSLS as substrate measured after 40 mins in presence of [gamma3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed