Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510034![]() (CHEMBL4593063) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510057![]() (CHEMBL4538655) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510035![]() (CHEMBL4528810) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510038![]() (CHEMBL4518161) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510039![]() (CHEMBL4456021) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510040![]() (CHEMBL4469611) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510041![]() (CHEMBL4476781) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510042![]() (CHEMBL4593172) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510043![]() (CHEMBL4524195) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510044![]() (CHEMBL4462808) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510045![]() (CHEMBL4587871) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510046![]() (CHEMBL4440380) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510047![]() (CHEMBL4517411) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510048![]() (CHEMBL4442568) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510037![]() (CHEMBL4463769) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510036![]() (CHEMBL4555958) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510054![]() (CHEMBL4445209) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510053![]() (CHEMBL4591499) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510051![]() (CHEMBL4527919) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510049![]() (CHEMBL4590631) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510052![]() (CHEMBL4446500) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510056![]() (CHEMBL4450681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510050![]() (CHEMBL4463485) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50510055![]() (CHEMBL4440787) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 1 (Mus musculus) | BDBM50000999![]() (CHEBI:81724 | DIMINAZENE) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Promidis Curated by ChEMBL | Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 | |||||||||||
More data for this Ligand-Target Pair |