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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for UniProtKB: P05363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurokinin 2 receptor


(Bos taurus)
BDBM50287397
PNG
(CGP-49823 | CHEMBL290364 | {(2R,4S)-2-Benzyl-4-[(q...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NCc1ccnc2ccccc12
Show InChI InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
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Article
n/an/a 2.79E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [125I]-NKA radioligand binding to NK2 receptor from bovine bladder


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair
Neurokinin 2 receptor


(Bos taurus)
BDBM50287399
PNG
(CHEMBL43912 | Quinoline-4-carboxylic acid [(2R,4S)...)
Show SMILES Clc1cc(Cl)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccccc1)NC(=O)c1ccnc2ccccc12
Show InChI InChI=1S/C29H25Cl2N3O2/c30-21-15-20(16-22(31)17-21)29(36)34-13-11-23(18-24(34)14-19-6-2-1-3-7-19)33-28(35)26-10-12-32-27-9-5-4-8-25(26)27/h1-10,12,15-17,23-24H,11,13-14,18H2,(H,33,35)/t23-,24+/m0/s1
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Article
n/an/a 4.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [125I]-NKA radioligand binding to NK2 receptor from bovine bladder


Bioorg Med Chem Lett 6: 1623-1628 (1996)


Article DOI: 10.1016/0960-894X(96)00287-9
BindingDB Entry DOI: 10.7270/Q2N016GN
More data for this
Ligand-Target Pair