BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ec50 for UniProtKB: P05362   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha


(Homo sapiens)
BDBM50157359
PNG
(4-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethy...)
Show SMILES CC(C)c1ccccc1Sc1ccc(cc1C(F)(F)F)-c1cc(ncn1)N1CCCC(C1)c1nnn[nH]1
Show InChI InChI=1S/C26H26F3N7S/c1-16(2)19-7-3-4-8-22(19)37-23-10-9-17(12-20(23)26(27,28)29)21-13-24(31-15-30-21)36-11-5-6-18(14-36)25-32-34-35-33-25/h3-4,7-10,12-13,15-16,18H,5-6,11,14H2,1-2H3,(H,32,33,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration to measure the adherence of LFA-1 expressing JY8 cells to immobilized ICAM-1 in cell-based adhesion assay


Bioorg Med Chem Lett 15: 195-201 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.008
BindingDB Entry DOI: 10.7270/Q2KD1XFD
More data for this
Ligand-Target Pair
Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha


(Homo sapiens)
BDBM50157352
PNG
(1-{6-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluorome...)
Show SMILES CC(C)c1ccccc1Sc1ccc(cc1C(F)(F)F)-c1cc(ncn1)N1CCCC(C1)C(O)=O
Show InChI InChI=1S/C26H26F3N3O2S/c1-16(2)19-7-3-4-8-22(19)35-23-10-9-17(12-20(23)26(27,28)29)21-13-24(31-15-30-21)32-11-5-6-18(14-32)25(33)34/h3-4,7-10,12-13,15-16,18H,5-6,11,14H2,1-2H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Effective concentration to measure the adherence of LFA-1 expressing JY8 cells to immobilized ICAM-1 in cell-based adhesion assay


Bioorg Med Chem Lett 15: 195-201 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.008
BindingDB Entry DOI: 10.7270/Q2KD1XFD
More data for this
Ligand-Target Pair