Compile Data Set for Download or QSAR
maximum 50k data
Found 386 of ic50 data for polymerid = 50001641,50007712
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50466629(CHEMBL4280766)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50466636(CHEMBL4286441)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50431662(CHEMBL2349246)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175938(1,3-bis(4-(7-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175931(1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175936(1,3-bis(4-(6-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50506597(CHEMBL4576477)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant HPSE GS3 (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 based colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50466651(CHEMBL4283251)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165639((2-{4-[2-(2,4-Dichloro-phenylcarbamoyl)-vinyl]-2-f...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165669((2-{4-[2-(3-Bromo-phenylcarbamoyl)-vinyl]-2-fluoro...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165653((2-{4-[2-(3,4-Dichloro-phenylcarbamoyl)-vinyl]-2-f...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50147546(2-(3-(5-(benzo[d][1,3]dioxol-5-yl)benzo[d]oxazol-2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165669((2-{4-[2-(3-Bromo-phenylcarbamoyl)-vinyl]-2-fluoro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165653((2-{4-[2-(3,4-Dichloro-phenylcarbamoyl)-vinyl]-2-f...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165639((2-{4-[2-(2,4-Dichloro-phenylcarbamoyl)-vinyl]-2-f...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50147513(2-[3-[5-(4-Chloro-phenyl)-benzooxazol-2-yl]-4-(2-m...)
Affinity DataIC50:  200nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50147546(2-(3-(5-(benzo[d][1,3]dioxol-5-yl)benzo[d]oxazol-2...)
Affinity DataIC50:  200nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50431663(CHEMBL2349247)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50375289(CHEMBL258980)
Affinity DataIC50:  250nMAssay Description:Inhibition of human platelet heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-Dioxo-2-[3-(5-phenyl-benzooxazol-2-yl)-4-propy...)
Affinity DataIC50:  250nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-Dioxo-2-[3-(5-phenyl-benzooxazol-2-yl)-4-propy...)
Affinity DataIC50:  251nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175939(1,3-bis-[4-(1H-benzoimidazol-2-yl)phenyl]urea | CH...)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175939(1,3-bis-[4-(1H-benzoimidazol-2-yl)phenyl]urea | CH...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175813(CHEMBL200831 | N-(4-{[5-(1H-benzoimidazol-2-yl)-py...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175813(CHEMBL200831 | N-(4-{[5-(1H-benzoimidazol-2-yl)-py...)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165640(2-(4-(5-(2-chloro-4-(3-(2,4-dichlorophenyl)acrylam...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165638((2-{4-[2-(4-Cyano-phenylcarbamoyl)-vinyl]-2-fluoro...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165627((2-{4-[2-(3-Fluoro-4-methoxy-phenylcarbamoyl)-viny...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165614((2-{4-[3-((E)-3-Chloro-2-fluoro-phenyl)-acryloylam...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165640(2-(4-(5-(2-chloro-4-(3-(2,4-dichlorophenyl)acrylam...)
Affinity DataIC50:  302nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165614((2-{4-[3-((E)-3-Chloro-2-fluoro-phenyl)-acryloylam...)
Affinity DataIC50:  302nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165638((2-{4-[2-(4-Cyano-phenylcarbamoyl)-vinyl]-2-fluoro...)
Affinity DataIC50:  302nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165627((2-{4-[2-(3-Fluoro-4-methoxy-phenylcarbamoyl)-viny...)
Affinity DataIC50:  302nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50412099(CHEMBL522358)
Affinity DataIC50:  347nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50412096(CHEMBL495405)
Affinity DataIC50:  347nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50462074(CHEMBL4251007)
Affinity DataIC50:  350nMAssay Description:Inhibition of activation of recombinant human pro-heparanase expressed in CHO cells by dimethylmethylene blue based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165624((2-{4-[3-((E)-2,4-Dichloro-phenyl)-acryloylamino]-...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165621((2-{2-Chloro-4-[3-((E)-2,4-dichloro-phenyl)-acrylo...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibitory concentration against human HeparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50466634(CHEMBL4290499)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant HPSE GS3 (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 based colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50:  393nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165613((2-{4-[3-((E)-4-Bromo-phenyl)-acryloylamino]-2-chl...)
Affinity DataIC50:  398nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50165620(2-(4-(5-(2-chloro-4-(3-(4-methoxyphenyl)acrylamido...)
Affinity DataIC50:  398nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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