Compile Data Set for Download or QSAR
maximum 50k data
Found 122 of ic50 data for polymerid = 50003119
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50226103((2S,3R)-ethyl 3-((S)-2-((S)-2-(benzyloxycarbonyl)-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM12042((2R,3R)-3-{[(1S)-1-[(4-carbamimidamidobutyl)carbam...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense MVAT4 rhodesain expressed in Pichia pastoris using Z-FR-AMC as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311247((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311248((S)-3-phenyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311250((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463157(CHEMBL4244656)
Affinity DataIC50:  20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463154(CHEMBL4251480)
Affinity DataIC50:  30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463142(CHEMBL4238441)
Affinity DataIC50:  30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50226104((2R,3S)-ethyl 3-((S)-2-((S)-2-(benzyloxycarbonyl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311246((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268555(6-(3-(furan-3-yl)benzylamino)-9-(3-hydroxypropyl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157207((1E,2E)-1-(3,4-dichlorophenyl)-3-phenylprop-2-en-1...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157211((E)-(3,4-dichlorophenyl)(4-methylphenyl)methanone ...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311251((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114651((1E)-1-(3-bromophenyl)ethan-1-one thiosemicarbazon...)
Affinity DataIC50:  50nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311249((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157210((E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)metha...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157204((1E)-1-(3,4-dichlorophenyl)pentan-1-one thiosemica...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157206((1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one t...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157205((1E)-1-(3,4-dichlorophenyl)-2-phenylethan-1-one th...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50:  90nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157209((1E)-1-(3,4-dichlorophenyl)-3-phenylpropan-1-one t...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311252((1R,2R)-2-(4-chlorobenzoyl)-N-((S)-5-phenyl-1-(phe...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by fluorescence techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463147(CHEMBL4237990)
Affinity DataIC50:  110nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114608((1E)-1-(3,4-dichlorophenyl)propan-1-one thiosemica...)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50:  140nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50:  145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463152(CHEMBL4242138)
Affinity DataIC50:  150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463148(CHEMBL4247707)
Affinity DataIC50:  150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114613((1E)-1-(3-bromophenyl)propan-1-one thiosemicarbazo...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268557(9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300773(6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268616(9-(3-hydroxypropyl)-6-(3-(pyridin-3-yl)benzylamino...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268554(6-(3-(furan-2-yl)benzylamino)-9-(3-hydroxypropyl)-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148061((1Z)-1-{3-[(1E)-N-(aminocarbonothioyl)ethanehydraz...)
Affinity DataIC50:  330nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300774(CHEMBL570364 | N-(3'-((2-cyano-9-(3-hydroxypropyl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268446(CHEMBL496404 | methyl 3'-((2-cyano-9-(3-hydroxypro...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300772(6-(3-(1H-indol-5-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148055((1E)-1-(3-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50:  550nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463145(CHEMBL4244085)
Affinity DataIC50:  560nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463146(CHEMBL4240920)
Affinity DataIC50:  590nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268668(6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268553(9-(3-hydroxypropyl)-6-(3-(naphthalen-2-yl)benzylam...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268500(1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268556(9-(3-hydroxypropyl)-6-(3-(thiophen-2-yl)benzylamin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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