BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits of ic50 for UniProtKB: P04271   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
S-100 protein beta chain


(Homo sapiens)
BDBM34166
PNG
((2,4-dipiperidinophenyl)amine | 2,4-Di-piperidin-1...)
Show SMILES Nc1ccc(cc1N1CCCCC1)N1CCCCC1
Show InChI InChI=1S/C16H25N3/c17-15-8-7-14(18-9-3-1-4-10-18)13-16(15)19-11-5-2-6-12-19/h7-8,13H,1-6,9-12,17H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429682
PNG
(CHEMBL2335383)
Show SMILES COc1cc2n(C)c(=O)n(C)c2cc1N
Show InChI InChI=1S/C10H13N3O2/c1-12-7-4-6(11)9(15-3)5-8(7)13(2)10(12)14/h4-5H,11H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.80E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429681
PNG
(CHEMBL2094307 | DNDI1416906)
Show SMILES CCN(CC)c1ccc(N)c(C)c1
Show InChI InChI=1S/C11H18N2/c1-4-13(5-2)10-6-7-11(12)9(3)8-10/h6-8H,4-5,12H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.40E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429679
PNG
(CHEMBL2335386)
Show SMILES Oc1ccc(cc1)\N=C\C=N\c1ccc(O)cc1
Show InChI InChI=1S/C14H12N2O2/c17-13-5-1-11(2-6-13)15-9-10-16-12-3-7-14(18)8-4-12/h1-10,17-18H/b15-9+,16-10+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.28E+4n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429680
PNG
(CHEMBL2335384)
Show SMILES Nc1cc(ccc1N1CCCCC1)N1CCCCC1
Show InChI InChI=1S/C16H25N3/c17-15-13-14(18-9-3-1-4-10-18)7-8-16(15)19-11-5-2-6-12-19/h7-8,13H,1-6,9-12,17H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.15E+4n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429684
PNG
(4-(4-Methoxybenzylideneamino)Phenol | CHEMBL67238)
Show SMILES COc1ccc(\C=N\c2ccc(O)cc2)cc1
Show InChI InChI=1S/C14H13NO2/c1-17-14-8-2-11(3-9-14)10-15-12-4-6-13(16)7-5-12/h2-10,16H,1H3/b15-10+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.63E+4n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM50429683
PNG
(4-((4-(Phenylamino)Phenylimino)Methyl)Phenol | CHE...)
Show SMILES Oc1ccc(\C=N\c2ccc(Nc3ccccc3)cc2)cc1
Show InChI InChI=1S/C19H16N2O/c22-19-12-6-15(7-13-19)14-20-16-8-10-18(11-9-16)21-17-4-2-1-3-5-17/h1-14,21-22H/b20-14+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.21E+4n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
S-100 protein beta chain


(Homo sapiens)
BDBM45440
PNG
(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
Show InChI InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assay


Bioorg Med Chem 21: 1109-15 (2013)


Article DOI: 10.1016/j.bmc.2012.12.042
BindingDB Entry DOI: 10.7270/Q21C1Z6C
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)