Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ic50 for UniProtKB: O15146
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of MUSK (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50550246(PF06273340 | Pf-06273340)
Affinity DataIC50:  53nMAssay Description:Inhibition of MUSK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  54.4nMAssay Description:Inhibition of human MUSK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50343726((S)-5-fluoro-2-(1-(5-fluoropyridin-2-yl)ethylamino...)
Affinity DataIC50:  224nMAssay Description:Inhibition of human MuSkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human MUSK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM465748(2-(3-{2-amino-6-[1-(oxetan-3-yl)-1,2,3,6-tetrahydr...)
Affinity DataIC50:  306nMAssay Description:Inhibition of human MUSK expressed in baculovirus expression system by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50081537(CHEMBL3422092)
Affinity DataIC50:  690nMAssay Description:Inhibition of human MuSK by millipore radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MUSK (530 to end residues) using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P]AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MUSK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MUSK using MBP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50509949(CHEMBL4475216 | US11667631, Example 29)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MUSK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182493(CHEMBL3818247 | US9512121, 22)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MUSK (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged MUSK cytoplasmic domain (519 to 869 residues) expressed in baculovirus expression system using tyrosine-4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed