Found 22 hits of ic50 for UniProtKB: A0A024R9L7 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463126
 (CHEMBL4238599)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)[N+]([O-])=O)-c1ccco1 Show InChI InChI=1S/C22H15N3O4/c23-22(26)16-5-3-14(4-6-16)17-12-19(15-7-9-18(10-8-15)25(27)28)24-20(13-17)21-2-1-11-29-21/h1-13H,(H2,23,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463135
 (CHEMBL4243878)Show SMILES N#Cc1ccc(cc1)-c1cc(cc(n1)-c1ccco1)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C23H14N6O/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(25-20)22-2-1-11-30-22)16-7-9-18(10-8-16)23-26-28-29-27-23/h1-13H,(H,26,27,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463127
 (CHEMBL4237402)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)-c1cnco1)-c1ccco1 Show InChI InChI=1S/C25H17N3O3/c26-25(29)19-9-3-16(4-10-19)20-12-21(28-22(13-20)23-2-1-11-30-23)17-5-7-18(8-6-17)24-14-27-15-31-24/h1-15H,(H2,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463138
 (CHEMBL4240401)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C23H15N3O2/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(26-20)22-2-1-11-28-22)16-7-9-18(10-8-16)23(25)27/h1-13H,(H2,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463140
 (CHEMBL4240109)Show SMILES N#Cc1ccc(cc1)-c1cc(cc(n1)-c1ccco1)-c1ccccc1 Show InChI InChI=1S/C22H14N2O/c23-15-16-8-10-18(11-9-16)20-13-19(17-5-2-1-3-6-17)14-21(24-20)22-7-4-12-25-22/h1-14H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463128
 (CHEMBL4249055)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)-c1nccs1)-c1ccco1 Show InChI InChI=1S/C25H17N3O2S/c26-24(29)18-7-3-16(4-8-18)20-14-21(28-22(15-20)23-2-1-12-30-23)17-5-9-19(10-6-17)25-27-11-13-31-25/h1-15H,(H2,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463131
 (CHEMBL4248559)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(n1)-c1ccco1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H14N4O2/c23-13-14-3-5-15(6-4-14)18-12-19(16-7-9-17(10-8-16)21(24)27)26-22(25-18)20-2-1-11-28-20/h1-12H,(H2,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463134
 (CHEMBL4246868)Show SMILES CS(=O)(=O)NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C24H17N3O4S/c1-32(29,30)27-24(28)19-10-8-17(9-11-19)20-13-21(18-6-4-16(15-25)5-7-18)26-22(14-20)23-3-2-12-31-23/h2-14H,1H3,(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463139
 (CHEMBL4243533)Show InChI InChI=1S/C13H9N3O/c14-8-12-7-11(5-6-16-12)9-1-3-10(4-2-9)13(15)17/h1-7H,(H2,15,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463130
 (CHEMBL4247460)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cncs1 Show InChI InChI=1S/C22H14N4OS/c23-11-14-1-3-16(4-2-14)19-9-18(10-20(26-19)21-12-25-13-28-21)15-5-7-17(8-6-15)22(24)27/h1-10,12-13H,(H2,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM93880
 (4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-benzoi...)Show SMILES OC(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1 Show InChI InChI=1S/C13H8N4O5/c18-13(19)7-1-3-8(4-2-7)14-9-5-6-10(17(20)21)12-11(9)15-22-16-12/h1-6,14H,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer... |
Bioorg Med Chem Lett 23: 370-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463141
 (CHEMBL4244986)Show SMILES Cn1nncc1-c1cc(cc(n1)-c1ccc(cc1)C#N)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C22H16N6O/c1-28-21(13-25-27-28)20-11-18(15-6-8-17(9-7-15)22(24)29)10-19(26-20)16-4-2-14(12-23)3-5-16/h2-11,13H,1H3,(H2,24,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463129
 (CHEMBL4245253)Show SMILES Cn1ccnc1-c1cc(cc(n1)-c1ccc(cc1)C#N)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C23H17N5O/c1-28-11-10-26-23(28)21-13-19(16-6-8-18(9-7-16)22(25)29)12-20(27-21)17-4-2-15(14-24)3-5-17/h2-13H,1H3,(H2,25,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM23926
 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi
Curated by ChEMBL
| Assay Description Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase treated 30 mins before induction |
J Nat Prod 76: 679-84 (2013)
Article DOI: 10.1021/np300893n BindingDB Entry DOI: 10.7270/Q2ZW1N83 |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50431277
 ((Z)-3,4,3'',5''-Tetramethoxystilbene | (Z)-3,4,3',...)Show InChI InChI=1S/C18H20O4/c1-19-15-9-14(10-16(12-15)20-2)6-5-13-7-8-17(21-3)18(11-13)22-4/h5-12H,1-4H3/b6-5- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi
Curated by ChEMBL
| Assay Description Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase treated 30 mins before induction |
J Nat Prod 76: 679-84 (2013)
Article DOI: 10.1021/np300893n BindingDB Entry DOI: 10.7270/Q2ZW1N83 |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463133
 (CHEMBL4240576)Show SMILES NNC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C23H16N4O2/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(26-20)22-2-1-11-29-22)16-7-9-18(10-8-16)23(28)27-25/h1-13H,25H2,(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463136
 (CHEMBL4248116)Show SMILES c1coc(c1)-c1cc(cc(n1)-c1ccc(cc1)-c1nccs1)-c1nccs1 Show InChI InChI=1S/C21H13N3OS2/c1-2-19(25-9-1)18-13-16(21-23-8-11-27-21)12-17(24-18)14-3-5-15(6-4-14)20-22-7-10-26-20/h1-13H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463132
 (CHEMBL4250683)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1cccc(F)c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C25H16FN3O/c26-22-3-1-2-20(12-22)24-14-21(17-8-10-19(11-9-17)25(28)30)13-23(29-24)18-6-4-16(15-27)5-7-18/h1-14H,(H2,28,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463137
 (CHEMBL4241092)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cnco1 Show InChI InChI=1S/C22H14N4O2/c23-11-14-1-3-16(4-2-14)19-9-18(10-20(26-19)21-12-25-13-28-21)15-5-7-17(8-6-15)22(24)27/h1-10,12-13H,(H2,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463125
 (CHEMBL4242611)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(n1)-c1cc[n+]([O-])cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H15N5O2/c24-14-15-1-3-16(4-2-15)20-13-21(17-5-7-18(8-6-17)22(25)29)27-23(26-20)19-9-11-28(30)12-10-19/h1-13H,(H2,25,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463124
 (CHEMBL4248050)Show SMILES COc1ccc(cc1)-c1cc(nc(n1)-c1ccccc1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C24H19N3O2/c1-29-20-13-11-17(12-14-20)22-15-21(16-7-9-18(10-8-16)23(25)28)26-24(27-22)19-5-3-2-4-6-19/h2-15H,1H3,(H2,25,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019 BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50423921
 (CHEMBL2312756)Show SMILES [O-][N+](=O)c1ccc(Nc2ccccc2-c2ccccc2)c2nonc12 Show InChI InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer... |
Bioorg Med Chem Lett 23: 370-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM |
More data for this Ligand-Target Pair | |