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Compile Data Set for Download or QSAR

Found 29 hits of ic50 data for polymerid = 50006094   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acidic mammalian chitinase


(Mus musculus)
BDBM50243685
PNG
(CHEMBL4084573)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)N(CCc1ccc(Cl)cc1)Cc1cccc2ccccc12
Show InChI InChI=1S/C26H29ClN6/c27-22-10-8-19(9-11-22)12-15-33(18-21-6-3-5-20-4-1-2-7-24(20)21)23-13-16-32(17-14-23)26-29-25(28)30-31-26/h1-11,23H,12-18H2,(H3,28,29,30,31)
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n/an/a 6.20n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243760
PNG
(CHEMBL4082060)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)N(CCc1ccc(Cl)cc1)CC1CCCCC1
Show InChI InChI=1S/C22H33ClN6/c23-19-8-6-17(7-9-19)10-13-29(16-18-4-2-1-3-5-18)20-11-14-28(15-12-20)22-25-21(24)26-27-22/h6-9,18,20H,1-5,10-16H2,(H3,24,25,26,27)
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n/an/a 8n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243746
PNG
(CHEMBL4068944)
Show SMILES CC(C)CN(CCc1ccc(Br)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C19H29BrN6/c1-14(2)13-26(10-7-15-3-5-16(20)6-4-15)17-8-11-25(12-9-17)19-22-18(21)23-24-19/h3-6,14,17H,7-13H2,1-2H3,(H3,21,22,23,24)
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n/an/a 8n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243795
PNG
(CHEMBL4077644)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)N(CCc1ccc(Cl)cc1)Cc1ccccc1Cl
Show InChI InChI=1S/C22H26Cl2N6/c23-18-7-5-16(6-8-18)9-12-30(15-17-3-1-2-4-20(17)24)19-10-13-29(14-11-19)22-26-21(25)27-28-22/h1-8,19H,9-15H2,(H3,25,26,27,28)
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n/an/a 9.70n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of [3H]WIN-35428 binding to the dopamine transporter


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243799
PNG
(CHEMBL4077482)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)N(CCc1ccc(Cl)cc1)Cc1ccccc1
Show InChI InChI=1S/C22H27ClN6/c23-19-8-6-17(7-9-19)10-13-29(16-18-4-2-1-3-5-18)20-11-14-28(15-12-20)22-25-21(24)26-27-22/h1-9,20H,10-16H2,(H3,24,25,26,27)
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n/an/a 11n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of [3H]GBR-12935 binding to the dopamine transporter.


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243745
PNG
(CHEMBL4076989)
Show SMILES CC(C)CN(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C19H29ClN6/c1-14(2)13-26(10-7-15-3-5-16(20)6-4-15)17-8-11-25(12-9-17)19-22-18(21)23-24-19/h3-6,14,17H,7-13H2,1-2H3,(H3,21,22,23,24)
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n/an/a 19n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243744
PNG
(CHEMBL4098997)
Show SMILES CCN(CCc1ccc(Br)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C17H25BrN6/c1-2-23(10-7-13-3-5-14(18)6-4-13)15-8-11-24(12-9-15)17-20-16(19)21-22-17/h3-6,15H,2,7-12H2,1H3,(H3,19,20,21,22)
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n/an/a 36n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243743
PNG
(CHEMBL4072036)
Show SMILES CCN(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C17H25ClN6/c1-2-23(10-7-13-3-5-14(18)6-4-13)15-8-11-24(12-9-15)17-20-16(19)21-22-17/h3-6,15H,2,7-12H2,1H3,(H3,19,20,21,22)
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n/an/a 95n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243742
PNG
(CHEMBL4086986)
Show SMILES CN(CCc1ccc(Br)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C16H23BrN6/c1-22(9-6-12-2-4-13(17)5-3-12)14-7-10-23(11-8-14)16-19-15(18)20-21-16/h2-5,14H,6-11H2,1H3,(H3,18,19,20,21)
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n/an/a 108n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243800
PNG
(CHEMBL4075848)
Show SMILES CC(C)N(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C18H27ClN6/c1-13(2)25(12-7-14-3-5-15(19)6-4-14)16-8-10-24(11-9-16)18-21-17(20)22-23-18/h3-6,13,16H,7-12H2,1-2H3,(H3,20,21,22,23)
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n/an/a 185n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of [3H]cocaine binding to the dopamine transporter.


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243807
PNG
(CHEMBL4065553)
Show SMILES CN(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C16H23ClN6/c1-22(9-6-12-2-4-13(17)5-3-12)14-7-10-23(11-8-14)16-19-15(18)20-21-16/h2-5,14H,6-11H2,1H3,(H3,18,19,20,21)
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n/an/a 245n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of [125I]RTI-55 cocaine binding to the dopamine transporter.


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243798
PNG
(CHEMBL4084148)
Show SMILES CN(CCc1ccc(Cl)cc1Cl)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C16H22Cl2N6/c1-23(7-4-11-2-3-12(17)10-14(11)18)13-5-8-24(9-6-13)16-20-15(19)21-22-16/h2-3,10,13H,4-9H2,1H3,(H3,19,20,21,22)
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n/an/a 333n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243691
PNG
(CHEMBL4081105)
Show SMILES CN(CCc1ccc(C)cc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C17H26N6/c1-13-3-5-14(6-4-13)7-10-22(2)15-8-11-23(12-9-15)17-19-16(18)20-21-17/h3-6,15H,7-12H2,1-2H3,(H3,18,19,20,21)
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n/an/a 544n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243704
PNG
(CHEMBL4068260)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)NS(=O)(=O)Cc1ccc(Br)cc1
Show InChI InChI=1S/C14H19BrN6O2S/c15-11-3-1-10(2-4-11)9-24(22,23)20-12-5-7-21(8-6-12)14-17-13(16)18-19-14/h1-4,12,20H,5-9H2,(H3,16,17,18,19)
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n/an/a 573n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243692
PNG
(CHEMBL4071081)
Show SMILES CC(C)c1ccc(CCN(C)C2CCN(CC2)c2nc(N)n[nH]2)cc1
Show InChI InChI=1S/C19H30N6/c1-14(2)16-6-4-15(5-7-16)8-11-24(3)17-9-12-25(13-10-17)19-21-18(20)22-23-19/h4-7,14,17H,8-13H2,1-3H3,(H3,20,21,22,23)
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n/an/a 1.29E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243701
PNG
(CHEMBL4098590)
Show SMILES Nc1n[nH]c(n1)N1CCN(CC1)C(=O)COc1ccc(Br)cc1
Show InChI InChI=1S/C14H17BrN6O2/c15-10-1-3-11(4-2-10)23-9-12(22)20-5-7-21(8-6-20)14-17-13(16)18-19-14/h1-4H,5-9H2,(H3,16,17,18,19)
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n/an/a 1.36E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243796
PNG
(CHEMBL4103842)
Show SMILES CCc1ccc(CCN(C)C2CCN(CC2)c2nc(N)n[nH]2)cc1
Show InChI InChI=1S/C18H28N6/c1-3-14-4-6-15(7-5-14)8-11-23(2)16-9-12-24(13-10-16)18-20-17(19)21-22-18/h4-7,16H,3,8-13H2,1-2H3,(H3,19,20,21,22)
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n/an/a 1.43E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243693
PNG
(CHEMBL4091907)
Show SMILES CN(CCc1ccc(cc1)C1CC1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C19H28N6/c1-24(11-8-14-2-4-15(5-3-14)16-6-7-16)17-9-12-25(13-10-17)19-21-18(20)22-23-19/h2-5,16-17H,6-13H2,1H3,(H3,20,21,22,23)
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n/an/a 1.74E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50378795
PNG
(CHEMBL1215473)
Show SMILES Nc1nnc([nH]1)N1CCN(CCOc2ccc(Br)cc2)CC1
Show InChI InChI=1S/C14H19BrN6O/c15-11-1-3-12(4-2-11)22-10-9-20-5-7-21(8-6-20)14-17-13(16)18-19-14/h1-4H,5-10H2,(H3,16,17,18,19)
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n/an/a 2.10E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM81508
PNG
(Bisdionin C)
Show SMILES Cn1cnc2n(C)c(=O)n(CCCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12
Show InChI InChI=1S/C17H20N8O4/c1-20-8-18-12-10(20)14(26)24(16(28)22(12)3)6-5-7-25-15(27)11-13(19-9-21(11)2)23(4)17(25)29/h8-9H,5-7H2,1-4H3
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n/an/a 3.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of AMCase in BALB/c mouse lung homogenate using 4-methyumbelliferyl-beta-B-N,N'-diacetylchitobiose after 10 mins


ACS Med Chem Lett 2: 428-432 (2011)


Article DOI: 10.1021/ml200008b
BindingDB Entry DOI: 10.7270/Q2RJ4KH7
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243694
PNG
(CHEMBL4067632)
Show SMILES CN(CCc1ccc(cc1)C(C)(C)C)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C20H32N6/c1-20(2,3)16-7-5-15(6-8-16)9-12-25(4)17-10-13-26(14-11-17)19-22-18(21)23-24-19/h5-8,17H,9-14H2,1-4H3,(H3,21,22,23,24)
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n/an/a 7.33E+3n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243686
PNG
(CHEMBL4062909)
Show SMILES CN(CCc1ccccc1)C1CCN(CC1)c1nc(N)n[nH]1
Show InChI InChI=1S/C16H24N6/c1-21(10-7-13-5-3-2-4-6-13)14-8-11-22(12-9-14)16-18-15(17)19-20-16/h2-6,14H,7-12H2,1H3,(H3,17,18,19,20)
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n/an/a 2.44E+4n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50388141
PNG
(CHEMBL1232048)
Show SMILES Cn1cnc2n(C)c(=O)n(CCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12
Show InChI InChI=1S/C16H18N8O4/c1-19-7-17-11-9(19)13(25)23(15(27)21(11)3)5-6-24-14(26)10-12(18-8-20(10)2)22(4)16(24)28/h7-8H,5-6H2,1-4H3
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n/an/a 9.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of AMCase in BALB/c mouse lung homogenate using 4-methyumbelliferyl-beta-B-N,N'-diacetylchitobiose after 10 mins


ACS Med Chem Lett 2: 428-432 (2011)


Article DOI: 10.1021/ml200008b
BindingDB Entry DOI: 10.7270/Q2RJ4KH7
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243809
PNG
(CHEMBL4071558)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C15H19BrN6O/c16-12-3-1-10(2-4-12)9-18-13(23)11-5-7-22(8-6-11)15-19-14(17)20-21-15/h1-4,11H,5-9H2,(H,18,23)(H3,17,19,20,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243716
PNG
(CHEMBL4079129)
Show SMILES CN(CC1CCN(CC1)c1nc(N)n[nH]1)Cc1ccc(Br)cc1
Show InChI InChI=1S/C16H23BrN6/c1-22(10-12-2-4-14(17)5-3-12)11-13-6-8-23(9-7-13)16-19-15(18)20-21-16/h2-5,13H,6-11H2,1H3,(H3,18,19,20,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243808
PNG
(CHEMBL4095625)
Show SMILES CN(C1CCN(CC1)c1nc(N)n[nH]1)S(=O)(=O)Cc1ccc(Br)cc1
Show InChI InChI=1S/C15H21BrN6O2S/c1-21(25(23,24)10-11-2-4-12(16)5-3-11)13-6-8-22(9-7-13)15-18-14(17)19-20-15/h2-5,13H,6-10H2,1H3,(H3,17,18,19,20)
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n/an/a>1.00E+5n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243741
PNG
(CHEMBL4103374)
Show SMILES Nc1n[nH]c(n1)N1CCC(CNC(=O)c2ccc(Br)cc2)CC1
Show InChI InChI=1S/C15H19BrN6O/c16-12-3-1-11(2-4-12)13(23)18-9-10-5-7-22(8-6-10)15-19-14(17)20-21-15/h1-4,10H,5-9H2,(H,18,23)(H3,17,19,20,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243703
PNG
(CHEMBL4087924)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)NC(=O)Cc1ccc(Br)cc1
Show InChI InChI=1S/C15H19BrN6O/c16-11-3-1-10(2-4-11)9-13(23)18-12-5-7-22(8-6-12)15-19-14(17)20-21-15/h1-4,12H,5-9H2,(H,18,23)(H3,17,19,20,21)
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OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair
Acidic mammalian chitinase


(Mus musculus)
BDBM50243702
PNG
(CHEMBL4059615)
Show SMILES Nc1n[nH]c(n1)N1CCC(CC1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C14H18BrN7O/c15-9-1-3-10(4-2-9)17-14(23)18-11-5-7-22(8-6-11)13-19-12(16)20-21-13/h1-4,11H,5-8H2,(H2,17,18,23)(H3,16,19,20,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



OncoArendi Therapeutics SA

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant full length C-terminal His-tagged acidic mammalian chitinase expressed in CHO-K1 cells using 4-methylumbelliferyl-bet...


J Med Chem 61: 695-710 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01051
More data for this
Ligand-Target Pair