Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ec50 data for polymerid = 50006595
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526580(CHEMBL4549036)
Affinity DataEC50:  530nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81292(8-Bromoadenosine 3',5'-cyclic monophosphat...)
Affinity DataEC50:  1.09E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50450837(8-pCPT-2''-O-Me-cAMP | CHEMBL397985)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of EPAC1 DEP1 deletion mutant (unknown origin) expressed in mouse NIH-3T3-A14 cells assessed as increase in Rap1b- fluorescent nucleotide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526578(CHEMBL4468490)
Affinity DataEC50:  2.75E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50511918(CHEMBL4450888)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of recombinant EPAC1 (149 to 881 residues) (unknown origin) assessed as stimulation of dissociation of fluorescent MANT-GDP from recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50511914(CHEMBL4576925)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of recombinant EPAC1 (149 to 881 residues) (unknown origin) assessed as stimulation of dissociation of fluorescent MANT-GDP from recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50511915(CHEMBL4517829)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of recombinant EPAC1 (149 to 881 residues) (unknown origin) assessed as stimulation of dissociation of fluorescent MANT-GDP from recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81289(Adenosine 3',5'-cyclic monophosphate sodiu...)
Affinity DataEC50:  5.62E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed