Found 13 hits of kd for UniProtKB: A0A024QYT5 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92482
(CDE-008 | US9120744, CDE-008)Show SMILES Oc1cc(cc(O)c1O)C(=O)OCCOC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C16H14O10/c17-9-3-7(4-10(18)13(9)21)15(23)25-1-2-26-16(24)8-5-11(19)14(22)12(20)6-8/h3-6,17-22H,1-2H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 23 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92487
(CDE-031 | US9120744, CDE-031)Show SMILES Oc1cc(cc(O)c1O)C(=O)O[C@@H]1CCCC[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H20O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h5-8,15-16,21-26H,1-4H2/t15-,16+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 31 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92483
(CDE-034 | US9120744, CDE-034)Show SMILES Oc1cc(cc(O)c1O)C(=O)O[C@@H]1CCCC[C@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H20O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h5-8,15-16,21-26H,1-4H2/t15-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 67 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92484
(CDE-056 | US9120744, CDE-056)Show SMILES Oc1cc(cc(O)c1O)C(=O)Oc1ccccc1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H14O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h1-8,21-26H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 51 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92485
(CDE-066 | US9120744, CDE-066)Show SMILES Oc1cc(cc(O)c1O)C(=O)OC[C@H]1OC(OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33+,34+,35-,41?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92486
(CDE-082 | US9120744, CDE-082)Show SMILES Oc1cc(cc(O)c1O)C(=O)OCC(COC(=O)c1cc(O)c(O)c(O)c1)OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C24H20O15/c25-13-1-9(2-14(26)19(13)31)22(34)37-7-12(39-24(36)11-5-17(29)21(33)18(30)6-11)8-38-23(35)10-3-15(27)20(32)16(28)4-10/h1-6,12,25-33H,7-8H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.30 | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description
Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967
BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM50149275
(2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...)Show SMILES OC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School
Curated by ChEMBL
| Assay Description
Binding affinity to human immobilized PAI1 by surface plasmon resonance |
J Biol Chem 282: 9288-96 (2007)
Article DOI: 10.1074/jbc.M611642200
BindingDB Entry DOI: 10.7270/Q2FF3S51 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92487
(CDE-031 | US9120744, CDE-031)Show SMILES Oc1cc(cc(O)c1O)C(=O)O[C@@H]1CCCC[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H20O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h5-8,15-16,21-26H,1-4H2/t15-,16+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 31 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92483
(CDE-034 | US9120744, CDE-034)Show SMILES Oc1cc(cc(O)c1O)C(=O)O[C@@H]1CCCC[C@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H20O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h5-8,15-16,21-26H,1-4H2/t15-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 67 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92484
(CDE-056 | US9120744, CDE-056)Show SMILES Oc1cc(cc(O)c1O)C(=O)Oc1ccccc1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H14O10/c21-11-5-9(6-12(22)17(11)25)19(27)29-15-3-1-2-4-16(15)30-20(28)10-7-13(23)18(26)14(24)8-10/h1-8,21-26H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 51 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92485
(CDE-066 | US9120744, CDE-066)Show SMILES Oc1cc(cc(O)c1O)C(=O)OC[C@H]1OC(OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33+,34+,35-,41?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92486
(CDE-082 | US9120744, CDE-082)Show SMILES Oc1cc(cc(O)c1O)C(=O)OCC(COC(=O)c1cc(O)c(O)c(O)c1)OC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C24H20O15/c25-13-1-9(2-14(26)19(13)31)22(34)37-7-12(39-24(36)11-5-17(29)21(33)18(30)6-11)8-38-23(35)10-3-15(27)20(32)16(28)4-10/h1-6,12,25-33H,7-8H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| KEGG
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 5.30 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM92482
(CDE-008 | US9120744, CDE-008)Show SMILES Oc1cc(cc(O)c1O)C(=O)OCCOC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C16H14O10/c17-9-3-7(4-10(18)13(9)21)15(23)25-1-2-26-16(24)8-5-11(19)14(22)12(20)6-8/h3-6,17-22H,1-2H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | 23 | n/a | n/a | n/a | 5.0 | 23 |
University of Michigan
US Patent
| Assay Description
To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con... |
US Patent US9120744 (2015)
BindingDB Entry DOI: 10.7270/Q2QF8RN8 |
More data for this
Ligand-Target Pair | |
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