BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 10 hits of ki for UniProtKB: A0A098ZGI7   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM50026863
PNG
(CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA...)
Show SMILES O=Cc1cccnc1
Show InChI InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92852
PNG
(Nicotinamidase Inhibitor, 19)
Show SMILES Cc1cncc(C=O)c1
Show InChI InChI=1S/C7H7NO/c1-6-2-7(5-9)4-8-3-6/h2-5H,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
56n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92850
PNG
(Nicotinamidase Inhibitor, 17)
Show SMILES Brc1cncc(C=O)c1
Show InChI InChI=1S/C6H4BrNO/c7-6-1-5(4-9)2-8-3-6/h1-4H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
71n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92851
PNG
(Nicotinamidase Inhibitor, 18)
Show SMILES COc1cncc(C=O)c1
Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
140n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92854
PNG
(Nicotinamidase Inhibitor, 21)
Show SMILES Fc1ccc(C=O)cn1
Show InChI InChI=1S/C6H4FNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
730n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92855
PNG
(Nicotinamidase Inhibitor, 22)
Show SMILES COc1ccncc1C=O
Show InChI InChI=1S/C7H7NO2/c1-10-7-2-3-8-4-6(7)5-9/h2-5H,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
5.00E+4n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92857
PNG
(Nicotinamidase Inhibitor, 24)
Show SMILES CC(=O)c1cccnc1
Show InChI InChI=1S/C7H7NO/c1-6(9)7-3-2-4-8-5-7/h2-5H,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
6.00E+4n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92853
PNG
(Nicotinamidase Inhibitor, 20)
Show SMILES Clc1ncccc1C=O
Show InChI InChI=1S/C6H4ClNO/c7-6-5(4-9)2-1-3-8-6/h1-4H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
1.10E+5n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM92856
PNG
(Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5)
Show SMILES N#Cc1cccnc1
Show InChI InChI=1S/C6H4N2/c7-4-6-2-1-3-8-5-6/h1-3,5H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
5.00E+5n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair
Nicotinamidase (SpNic)


(Streptococcus pneumoniae)
BDBM23515
PNG
(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Show SMILES OC(=O)c1cccnc1
Show InChI InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
2.00E+6n/an/an/an/an/an/an/an/a



Cornell University



Assay Description
Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...


Biochemistry 49: 10421-39 (2010)


Article DOI: 10.1021/bi1012518
BindingDB Entry DOI: 10.7270/Q2G44NWC
More data for this
Ligand-Target Pair