Compile Data Set for Download or QSAR
maximum 50k data
Found 91 of ic50 data for polymerid = 5445
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046841(CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368802(CHEMBL1791097)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407080(CHEMBL2112254)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407074(CHEMBL2112267)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407089(CHEMBL2112253)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407087(CHEMBL2112258)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407076(CHEMBL2112270)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407075(CHEMBL2112262)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407070(CHEMBL2112268)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046820(4-Methyl-piperazine-1-carboxylic acid {2-cyclohexy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407071(CHEMBL2112257)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368795(CHEMBL1791129)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368810(CHEMBL1791125)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407072(CHEMBL2112269)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM97371(ECE Inhibitor, 14)
Affinity DataIC50:  10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368814(CHEMBL1791126)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407088(CHEMBL2112255)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368798(CHEMBL1791120)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407086(CHEMBL2112265)
Affinity DataIC50:  12nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407078(CHEMBL2112272)
Affinity DataIC50:  13nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046842(3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...)
Affinity DataIC50:  13nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046857(CHEMBL143596 | [1-(1-{1-[1-Hydroxy-2-(4-hydroxy-bu...)
Affinity DataIC50:  13nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368806(CHEMBL1791099)
Affinity DataIC50:  15nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368788(CHEMBL1791112)
Affinity DataIC50:  16nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407090(CHEMBL2112837)
Affinity DataIC50:  16nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407083(CHEMBL2112251)
Affinity DataIC50:  17nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287866((S)-2-[3-(3-Bromo-phenyl)-2-mercaptomethyl-propion...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046856(CHEMBL143902 | [1-(1-{1-[1-Hydroxy-2-(5-hydroxy-pe...)
Affinity DataIC50:  21nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368799(CHEMBL1791102)
Affinity DataIC50:  23nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407085(CHEMBL2112259)
Affinity DataIC50:  24nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287877((S)-2-[3-(4-Bromo-phenyl)-2-mercaptomethyl-propion...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407079(CHEMBL2112261)
Affinity DataIC50:  28nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368786(CHEMBL1791119)
Affinity DataIC50:  32nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287873((S)-2-(3-Biphenyl-3-yl-2-mercaptomethyl-propionyla...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287875((S)-2-(3-Biphenyl-4-yl-2-mercaptomethyl-propionyla...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50112397(CHEMBL22323 | Sodium;4-chloro-N-{[(4-cyano-3-methy...)
Affinity DataIC50:  42nMAssay Description:Tested in vitro for inhibition of Endothelin-converting enzyme (ECE) of rat lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407081(CHEMBL2112256)
Affinity DataIC50:  48nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287862((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407082(CHEMBL2112836)
Affinity DataIC50:  58nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046833(3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...)
Affinity DataIC50:  58nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407077(CHEMBL2112264)
Affinity DataIC50:  65nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046861(2-(2-Amino-3-cyclohexyl-propionylamino)-3-methyl-p...)
Affinity DataIC50:  68nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287872((S)-2-[3-(3-Bromo-phenyl)-2-mercaptomethyl-propion...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407084(CHEMBL2112271)
Affinity DataIC50:  94nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407091(CHEMBL2112266)
Affinity DataIC50:  100nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046826(4-[2-(2-tert-Butoxycarbonylamino-3,3-dimethyl-buty...)
Affinity DataIC50:  100nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046825(4-[2-(3-tert-Butoxy-2-tert-butoxycarbonylamino-but...)
Affinity DataIC50:  130nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287865((S)-3-Biphenyl-4-yl-2-((S)-2-mercaptomethyl-3-phen...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50287867((S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptomethyl-3-ph...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1 from rat lungs.More data for this Ligand-Target Pair
In DepthDetails Article
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