Compile Data Set for Download or QSAR
maximum 50k data
Found 41 of ki data for polymerid = 5525
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50072740((6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-py...)
Affinity DataKi:  0.600nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107062((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  7nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107060((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  8nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107064((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  14nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107063((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  78nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107067((S)-4-Oxo-2-phenylmethanesulfonyl-octahydro-pyrrol...)
Affinity DataKi:  100nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  100nM ΔG°:  -9.51kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107066((6S,8aS)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-py...)
Affinity DataKi:  180nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  480nM ΔG°:  -8.59kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98588((2S)-3-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...)
Affinity DataKi:  780nM ΔG°:  -8.30kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107065((S)-4-Oxo-2-(3-phenyl-propionyl)-octahydro-pyrrolo...)
Affinity DataKi:  900nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107061((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107059((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98601((2S)-6-[[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)...)
Affinity DataKi:  1.40E+3nM ΔG°:  -7.95kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98598((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  1.60E+3nM ΔG°:  -7.87kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98583(4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  2.30E+3nM ΔG°:  -7.66kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98589((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.33kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98581(US8476306, 6.6 | methyl 2-[[(1R)-2-[[2-[(4-carbami...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.33kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98593(US8476306, 6.19 | methyl 4-[[(1R)-2-[[(1S)-2-[(4-c...)
Affinity DataKi:  4.20E+3nM ΔG°:  -7.31kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98599((2S)-6-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...)
Affinity DataKi:  4.30E+3nM ΔG°:  -7.29kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98600((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...)
Affinity DataKi:  4.70E+3nM ΔG°:  -7.24kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98596((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  7.90E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98594((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  7.90E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98586((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...)
Affinity DataKi:  8.00E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98595((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  8.00E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98597((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  8.30E+3nM ΔG°:  -6.90kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98584(3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  8.30E+3nM ΔG°:  -6.90kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  8.50E+3nM ΔG°:  -6.89kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98585((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  8.50E+3nM ΔG°:  -6.89kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98579(US8476306, 6.4 | methyl 4-[[(1R)-2-[[2-[(4-carbami...)
Affinity DataKi:  9.40E+3nM ΔG°:  -6.83kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98602(3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.79kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50107058((6S,8aS)-4-Oxo-2-phenylmethanesulfonyl-octahydro-p...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro ability of the compound to inhibit the amidolytic activity of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50110015(CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...)
Affinity DataKi:  1.30E+4nM ΔG°:  -6.64kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  1.40E+4nM ΔG°:  -6.59kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50110015(CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...)
Affinity DataKi:  4.20E+4nM ΔG°:  -5.95kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98582(2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  5.60E+4nM ΔG°:  -5.78kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98604(2-[4-[[(1R)-2-[[2-[4-[(3-amino-4-methoxy-benzoyl)a...)
Affinity DataKi:  6.00E+4nM ΔG°:  -5.74kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98592(4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  1.20E+5nM ΔG°:  -5.33kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98578(3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  1.50E+5nM ΔG°:  -5.20kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98580(4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  1.70E+5nM ΔG°:  -5.12kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM98591(3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  2.00E+5nM ΔG°:  -5.03kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent