Compile Data Set for Download or QSAR
maximum 50k data
Found 736 of ec50 for UniProtKB: Q8JXU8
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235880(US9364482, 55)
Affinity DataEC50:  0.300nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235832(US9364482, 6)
Affinity DataEC50:  0.300nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235890(US9364482, 71)
Affinity DataEC50:  0.400nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50162095(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-p-tolyl-1...)
Affinity DataEC50:  0.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50162097(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methox...)
Affinity DataEC50:  0.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545012(CHEMBL4645241)
Affinity DataEC50:  0.5nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545010(CHEMBL4641600)
Affinity DataEC50:  0.5nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50162096(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(3-fluoro...)
Affinity DataEC50:  0.600nMAssay Description:Effective concentration for inhibitory activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545011(CHEMBL4644026)
Affinity DataEC50:  0.600nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545012(CHEMBL4645241)
Affinity DataEC50:  0.600nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235880(US9364482, 55)
Affinity DataEC50:  0.600nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235880(US9364482, 55)
Affinity DataEC50:  0.600nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503939(CHEMBL4568969)
Affinity DataEC50:  0.610nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503939(CHEMBL4568969)
Affinity DataEC50:  0.620nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3A infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503941(CHEMBL4590062)
Affinity DataEC50:  0.630nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4A infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503941(CHEMBL4590062)
Affinity DataEC50:  0.680nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235889(US9364482, 70)
Affinity DataEC50:  0.700nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545010(CHEMBL4641600)
Affinity DataEC50:  0.700nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235864(US9364482, 39)
Affinity DataEC50:  0.700nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235890(US9364482, 71)
Affinity DataEC50:  0.700nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235832(US9364482, 6)
Affinity DataEC50:  0.700nMAssay Description:Non-nucleoside inhibition of NS5B polymerase S365A mutant in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235890(US9364482, 71)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545006(CHEMBL4636179)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545010(CHEMBL4641600)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1b by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235869(US9364482, 44)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235893(US9364482, 74)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50162108(3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHE...)
Affinity DataEC50:  0.800nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235878(US9364482, 53)
Affinity DataEC50:  0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM204787(US9243002, 85)
Affinity DataEC50:  0.860nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50523163(CHEMBL4592781)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of HCV genotype 1a wild-type NS5B RNA dependent RNA polymerase transfected in human HuH7 Lunet replicon cells assessed as reduction in vir...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50162104(2-(4-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataEC50:  0.900nMAssay Description:Effective concentration for inhibitory activity against NS5B polymerase of Hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545010(CHEMBL4641600)
Affinity DataEC50:  0.900nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235878(US9364482, 53)
Affinity DataEC50:  0.900nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545007(CHEMBL4639325)
Affinity DataEC50:  0.900nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503940(CHEMBL4435877)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM204780(US9243002, 82)
Affinity DataEC50:  0.950nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50523174(CHEMBL4548919)
Affinity DataEC50:  1nMAssay Description:Inhibition of HCV genotype 1a wild-type NS5B RNA dependent RNA polymerase transfected in human HuH7 Lunet replicon cells assessed as reduction in vir...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235891(US9364482, 72)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503941(CHEMBL4590062)
Affinity DataEC50:  1nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3A infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503940(CHEMBL4435877)
Affinity DataEC50:  1nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3A infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235892(US9364482, 73)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235864(US9364482, 39)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM208267(US9265773, 2)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase S365A mutant in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235887(US9364482, 68)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545009(CHEMBL4643882)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50503941(CHEMBL4590062)
Affinity DataEC50:  1nMAssay Description:Inhibition of NS5B polymerase S365A mutant in HCV genotype 1A infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM235867(US9364482, 42)
Affinity DataEC50:  1nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50545012(CHEMBL4645241)
Affinity DataEC50:  1.10nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1b by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM204753(US9243002, 72)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in HuH7 cells after 40 hrs by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50523164(CHEMBL4537114)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of HCV genotype 1a wild-type NS5B RNA dependent RNA polymerase transfected in human HuH7 Lunet replicon cells assessed as reduction in vir...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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