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Compile Data Set for Download or QSAR

Found 1405 hits of ic50 for UniProtKB: P01375   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235368
PNG
(US9393245, 98)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)C(=O)NC(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C27H28ClN5O4/c1-16(2)30-26(35)31-12-10-18(11-13-31)32-24-20-8-5-9-22(37-3)23(20)29-15-21(24)25(34)33(27(32)36)19-7-4-6-17(28)14-19/h4-9,14-16,18H,10-13H2,1-3H3,(H,30,35)
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n/an/a 0.300n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235381
PNG
(US9393245, 113)
Show InChI InChI=1S/C27H27ClN4O5/c1-27(2,3)37-26(35)30-12-11-18(15-30)31-23-19-9-6-10-21(36-4)22(19)29-14-20(23)24(33)32(25(31)34)17-8-5-7-16(28)13-17/h5-10,13-14,18H,11-12,15H2,1-4H3/t18-/m1/s1
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235366
PNG
(US9393245, 96)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(=O)(=O)C2CCS(=O)(=O)C2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C27H27ClN4O7S2/c1-39-23-7-3-6-21-24(23)29-15-22-25(21)31(27(34)32(26(22)33)19-5-2-4-17(28)14-19)18-8-11-30(12-9-18)41(37,38)20-10-13-40(35,36)16-20/h2-7,14-15,18,20H,8-13,16H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235364
PNG
(US9393245, 94)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(=O)(=O)N(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H26ClN5O5S/c1-28(2)37(34,35)29-12-10-17(11-13-29)30-23-19-8-5-9-21(36-3)22(19)27-15-20(23)24(32)31(25(30)33)18-7-4-6-16(26)14-18/h4-9,14-15,17H,10-13H2,1-3H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235363
PNG
(US9393245, 93)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(=O)(=O)C(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C26H27ClN4O5S/c1-16(2)37(34,35)29-12-10-18(11-13-29)30-24-20-8-5-9-22(36-3)23(20)28-15-21(24)25(32)31(26(30)33)19-7-4-6-17(27)14-19/h4-9,14-16,18H,10-13H2,1-3H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM77003
PNG
(3-(1-oxo-4-(4-(2-(pyrrolidin-1-yl)ethoxy)benzyloxy...)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(OCCN2CCCC2)cc1)C1CCC(=O)NC1=O
Show InChI InChI=1S/C26H29N3O5/c30-24-11-10-22(25(31)27-24)29-16-21-20(26(29)32)4-3-5-23(21)34-17-18-6-8-19(9-7-18)33-15-14-28-12-1-2-13-28/h3-9,22H,1-2,10-17H2,(H,27,30,31)
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n/an/a 0.520n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM65497
PNG
(CC-220 (Compound 6) | US9694015, 6.4S)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)[C@H]1CCC(=O)NC1=O
Show InChI InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m0/s1
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Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235367
PNG
(US9393245, 97)
Show SMILES CCNC(=O)N1CCC(CC1)n1c2c3cccc(OC)c3ncc2c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C26H26ClN5O4/c1-3-28-25(34)30-12-10-17(11-13-30)31-23-19-8-5-9-21(36-2)22(19)29-15-20(23)24(33)32(26(31)35)18-7-4-6-16(27)14-18/h4-9,14-15,17H,3,10-13H2,1-2H3,(H,28,34)
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM77008
PNG
(3-{4-[4-(2-morpholin-4-yl-ethyl)-benzyloxy]-1-oxo-...)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(CCN2CCOCC2)cc1)C1CCC(=O)NC1=O
Show InChI InChI=1S/C26H29N3O5/c30-24-9-8-22(25(31)27-24)29-16-21-20(26(29)32)2-1-3-23(21)34-17-19-6-4-18(5-7-19)10-11-28-12-14-33-15-13-28/h1-7,22H,8-17H2,(H,27,30,31)
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n/an/a 0.790n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235370
PNG
(US9393245, 100)
Show SMILES COc1cccc2c1ncc1c2n(C2CCC(C)CC2)c(=O)n(-c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C25H24ClN3O3/c1-15-6-10-17(11-7-15)28-23-19-4-3-5-21(32-2)22(19)27-14-20(23)24(30)29(25(28)31)18-12-8-16(26)9-13-18/h3-5,8-9,12-15,17H,6-7,10-11H2,1-2H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM77005
PNG
(3-(4-(4-(2-morpholin-4-yl-ethoxy)-benzyloxy)-1-oxo...)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(OCCN2CCOCC2)cc1)C1CCC(=O)NC1=O
Show InChI InChI=1S/C26H29N3O6/c30-24-9-8-22(25(31)27-24)29-16-21-20(26(29)32)2-1-3-23(21)35-17-18-4-6-19(7-5-18)34-15-12-28-10-13-33-14-11-28/h1-7,22H,8-17H2,(H,27,30,31)
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Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235350
PNG
(US9393245, 78)
Show SMILES COc1cccc2c1ncc1c2n(C2CCC(C)CC2)c(=O)n(-c2cccc(C)c2)c1=O
Show InChI InChI=1S/C26H27N3O3/c1-16-10-12-18(13-11-16)28-24-20-8-5-9-22(32-3)23(20)27-15-21(24)25(30)29(26(28)31)19-7-4-6-17(2)14-19/h4-9,14-16,18H,10-13H2,1-3H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235359
PNG
(US9393245, 88)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)C(=O)OC(C)(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C28H29ClN4O5/c1-28(2,3)38-27(36)31-13-11-18(12-14-31)32-24-20-9-6-10-22(37-4)23(20)30-16-21(24)25(34)33(26(32)35)19-8-5-7-17(29)15-19/h5-10,15-16,18H,11-14H2,1-4H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235375
PNG
(US9393245, 107)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)C(=O)OC(C)(C)C)c(=O)n(-c2ccc3OCOc3c2)c1=O
Show InChI InChI=1S/C29H30N4O7/c1-29(2,3)40-28(36)31-12-10-17(11-13-31)32-25-19-6-5-7-22(37-4)24(19)30-15-20(25)26(34)33(27(32)35)18-8-9-21-23(14-18)39-16-38-21/h5-9,14-15,17H,10-13,16H2,1-4H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235355
PNG
(US9393245, 83)
Show SMILES CCCCn1c2c3cccc(OC)c3ncc2c(=O)n(-c2cccc(C)c2)c1=O
Show InChI InChI=1S/C23H23N3O3/c1-4-5-12-25-21-17-10-7-11-19(29-3)20(17)24-14-18(21)22(27)26(23(25)28)16-9-6-8-15(2)13-16/h6-11,13-14H,4-5,12H2,1-3H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135819
PNG
(US8853226, 103 | US9393245, 103)
Show SMILES COc1cccc2c1ncc1c2n(C2CC[C@@H](CC2)C(O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H22ClN3O5/c1-34-20-7-3-6-18-21(20)27-13-19-22(18)28(16-10-8-14(9-11-16)24(31)32)25(33)29(23(19)30)17-5-2-4-15(26)12-17/h2-7,12-14,16H,8-11H2,1H3,(H,31,32)/t14-,16?
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235365
PNG
(US9393245, 95)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(=O)(=O)c2ccccc2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C29H25ClN4O5S/c1-39-25-12-6-11-23-26(25)31-18-24-27(23)33(29(36)34(28(24)35)21-8-5-7-19(30)17-21)20-13-15-32(16-14-20)40(37,38)22-9-3-2-4-10-22/h2-12,17-18,20H,13-16H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235362
PNG
(US9393245, 91)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)C(=O)c2ccccc2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C30H25ClN4O4/c1-39-25-12-6-11-23-26(25)32-18-24-27(23)34(30(38)35(29(24)37)22-10-5-9-20(31)17-22)21-13-15-33(16-14-21)28(36)19-7-3-2-4-8-19/h2-12,17-18,21H,13-16H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM77001
PNG
(3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoisoin...)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)C1CCC(=O)NC1=O
Show InChI InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)
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n/an/a 1.80n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235390
PNG
(US9393245, 126)
Show SMILES COc1cccc2c1ncc1c2n(CC2CCN(CC2)S(C)(=O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H25ClN4O5S/c1-35-21-8-4-7-19-22(21)27-14-20-23(19)29(15-16-9-11-28(12-10-16)36(2,33)34)25(32)30(24(20)31)18-6-3-5-17(26)13-18/h3-8,13-14,16H,9-12,15H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235361
PNG
(US9393245, 90)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)C(C)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H23ClN4O4/c1-15(31)28-11-9-17(10-12-28)29-23-19-7-4-8-21(34-2)22(19)27-14-20(23)24(32)30(25(29)33)18-6-3-5-16(26)13-18/h3-8,13-14,17H,9-12H2,1-2H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235358
PNG
(US9393245, 87)
Show SMILES COc1cccc2c1ncc1c2n(C2CCC(F)(F)CC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C24H20ClF2N3O3/c1-33-19-7-3-6-17-20(19)28-13-18-21(17)29(15-8-10-24(26,27)11-9-15)23(32)30(22(18)31)16-5-2-4-14(25)12-16/h2-7,12-13,15H,8-11H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135817
PNG
(US8853226, 84 | US9393245, 84)
Show SMILES COc1cccc2c1ncc1c2n(C2CCCC2)c(=O)n(-c2ccc3OCOc3c2)c1=O
Show InChI InChI=1S/C24H21N3O5/c1-30-19-8-4-7-16-21(19)25-12-17-22(16)26(14-5-2-3-6-14)24(29)27(23(17)28)15-9-10-18-20(11-15)32-13-31-18/h4,7-12,14H,2-3,5-6,13H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235383
PNG
(US9393245, 116)
Show SMILES COc1cccc2c1ncc1c2n([C@H]2CCN(C2)C(=O)OC(C)(C)C)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C27H27ClN4O5/c1-27(2,3)37-26(35)30-12-11-18(15-30)31-23-19-9-6-10-21(36-4)22(19)29-14-20(23)24(33)32(25(31)34)17-8-5-7-16(28)13-17/h5-10,13-14,18H,11-12,15H2,1-4H3/t18-/m0/s1
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135818
PNG
(US8853226, 92 | US9393245, 92)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(C)(=O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C24H23ClN4O5S/c1-34-20-8-4-7-18-21(20)26-14-19-22(18)28(16-9-11-27(12-10-16)35(2,32)33)24(31)29(23(19)30)17-6-3-5-15(25)13-17/h3-8,13-14,16H,9-12H2,1-2H3
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n/an/a 2.40n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235374
PNG
(US9393245, 106)
Show SMILES COc1cccc2c1ncc1c2n(C2CCCCC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C24H22ClN3O3/c1-31-20-12-6-11-18-21(20)26-14-19-22(18)27(16-8-3-2-4-9-16)24(30)28(23(19)29)17-10-5-7-15(25)13-17/h5-7,10-14,16H,2-4,8-9H2,1H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235344
PNG
(US9393245, 72)
Show SMILES COc1cccc2c1ncc1c2n(C2CCC(C)CC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H24ClN3O3/c1-15-9-11-17(12-10-15)28-23-19-7-4-8-21(32-2)22(19)27-14-20(23)24(30)29(25(28)31)18-6-3-5-16(26)13-18/h3-8,13-15,17H,9-12H2,1-2H3
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vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235360
PNG
(US9393245, 89)
Show SMILES COc1cccc2c1ncc1c2n(C2CCNCC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C23H21ClN4O3/c1-31-19-7-3-6-17-20(19)26-13-18-21(17)27(15-8-10-25-11-9-15)23(30)28(22(18)29)16-5-2-4-14(24)12-16/h2-7,12-13,15,25H,8-11H2,1H3
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n/an/a 5n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235347
PNG
(US9393245, 75)
Show SMILES CCc1cccc(c1)-n1c(=O)n(C2CCCC2)c2c3cccc(OC)c3ncc2c1=O
Show InChI InChI=1S/C25H25N3O3/c1-3-16-8-6-11-18(14-16)28-24(29)20-15-26-22-19(12-7-13-21(22)31-2)23(20)27(25(28)30)17-9-4-5-10-17/h6-8,11-15,17H,3-5,9-10H2,1-2H3
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n/an/a 6n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135816
PNG
(US8853226, 54 | US9393245, 54)
Show SMILES COc1cccc2c1ncc1c2n(C2CCCC2)c(=O)n(-c2cccc(C)c2)c1=O
Show InChI InChI=1S/C24H23N3O3/c1-15-7-5-10-17(13-15)27-23(28)19-14-25-21-18(11-6-12-20(21)30-2)22(19)26(24(27)29)16-8-3-4-9-16/h5-7,10-14,16H,3-4,8-9H2,1-2H3
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n/an/a 6n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135824
PNG
(US8853226, 127 | US9393245, 127)
Show SMILES COc1cccc2c1ncc1c2n(C2CC[C@@H](CC2)NS(C)(=O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C25H25ClN4O5S/c1-35-21-8-4-7-19-22(21)27-14-20-23(19)29(17-11-9-16(10-12-17)28-36(2,33)34)25(32)30(24(20)31)18-6-3-5-15(26)13-18/h3-8,13-14,16-17,28H,9-12H2,1-2H3/t16-,17?
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n/an/a 6n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235377
PNG
(US9393245, 109)
Show SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(C)(=O)=O)c(=O)n(-c2ccc3OCOc3c2)c1=O
Show InChI InChI=1S/C25H24N4O7S/c1-34-20-5-3-4-17-22(20)26-13-18-23(17)28(15-8-10-27(11-9-15)37(2,32)33)25(31)29(24(18)30)16-6-7-19-21(12-16)36-14-35-19/h3-7,12-13,15H,8-11,14H2,1-2H3
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n/an/a 8n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235345
PNG
(US9393245, 73)
Show SMILES COc1cccc2c1ncc1c2n(C2CCCC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C23H20ClN3O3/c1-30-19-11-5-10-17-20(19)25-13-18-21(17)26(15-7-2-3-8-15)23(29)27(22(18)28)16-9-4-6-14(24)12-16/h4-6,9-13,15H,2-3,7-8H2,1H3
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n/an/a 9n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM77015
PNG
((R)-3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoi...)
Show SMILES O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)[C@@H]1CCC(=O)NC1=O
Show InChI InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m1/s1
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n/an/a 9.5n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM50168737
PNG
((2R,3R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzene...)
Show SMILES C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(F)cc2Cl)cc1
Show InChI InChI=1S/C20H22ClFN2O6S/c1-20(26)9-2-10-24(18(20)19(25)23-27)31(28,29)16-7-5-15(6-8-16)30-12-13-3-4-14(22)11-17(13)21/h3-8,11,18,26-27H,2,9-10,12H2,1H3,(H,23,25)/t18-,20+/m0/s1
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n/an/a 10n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against TNF-alpha releasein LPS treated whole blood


Bioorg Med Chem Lett 15: 3385-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.037
BindingDB Entry DOI: 10.7270/Q25D8RCC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM102834
PNG
(US8541572, 911)
Show SMILES CCN1CCN(CC1)C(N=O)c1ccc(cc1)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O
Show InChI InChI=1S/C28H30N6O5/c1-3-32-12-14-33(15-13-32)24(31-38)20-6-4-19(5-7-20)10-11-28(26(36)29-27(37)30-28)18-34-17-21-8-9-22(39-2)16-23(21)25(34)35/h4-9,16,24H,3,12-15,17-18H2,1-2H3,(H2,29,30,36,37)/t24?,28-/m1/s1
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0.160n/a 20n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Inhibition assay using TNF-alpha.


US Patent US8541572 (2013)


BindingDB Entry DOI: 10.7270/Q2QC024J
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235369
PNG
(US9393245, 99)
Show SMILES COc1cccc2c1ncc1c2n(C2CCC(C)CC2)c(=O)n(-c2ccccc2Cl)c1=O
Show InChI InChI=1S/C25H24ClN3O3/c1-15-10-12-16(13-11-15)28-23-17-6-5-9-21(32-2)22(17)27-14-18(23)24(30)29(25(28)31)20-8-4-3-7-19(20)26/h3-9,14-16H,10-13H2,1-2H3
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n/an/a 20n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM62288
PNG
(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)
Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C24H21F3N2O2/c25-24(26,27)31-22-11-9-21(10-12-22)28-23(30)19-7-5-17(6-8-19)15-29-14-13-18-3-1-2-4-20(18)16-29/h1-12H,13-16H2,(H,28,30)
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n/an/a 24.4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135820
PNG
(US8853226, 115 | US9393245, 115)
Show SMILES COc1cccc2c1ncc1c2n([C@@H]2CCN(C2)S(C)(=O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C23H21ClN4O5S/c1-33-19-8-4-7-17-20(19)25-12-18-21(17)27(16-9-10-26(13-16)34(2,31)32)23(30)28(22(18)29)15-6-3-5-14(24)11-15/h3-8,11-12,16H,9-10,13H2,1-2H3/t16-/m1/s1
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n/an/a 29n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135821
PNG
(US8853226, 118 | US9393245, 118)
Show SMILES COc1cccc2c1ncc1c2n([C@H]2CCN(C2)S(C)(=O)=O)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C23H21ClN4O5S/c1-33-19-8-4-7-17-20(19)25-12-18-21(17)27(16-9-10-26(13-16)34(2,31)32)23(30)28(22(18)29)15-6-3-5-14(24)11-15/h3-8,11-12,16H,9-10,13H2,1-2H3/t16-/m0/s1
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n/an/a 29n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM135815
PNG
(US8853226, 51 | US9393245, 51)
Show SMILES COc1cccc2c1ncc1c2n(C2CCCC2)c(=O)n(-c2cc(C)cs2)c1=O
Show InChI InChI=1S/C22H21N3O3S/c1-13-10-18(29-12-13)25-21(26)16-11-23-19-15(8-5-9-17(19)28-2)20(16)24(22(25)27)14-6-3-4-7-14/h5,8-12,14H,3-4,6-7H2,1-2H3
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n/an/a 30n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM235382
PNG
(US9393245, 114)
Show SMILES COc1cccc2c1ncc1c2n([C@@H]2CCNC2)c(=O)n(-c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C22H19ClN4O3/c1-30-18-7-3-6-16-19(18)25-12-17-20(16)26(15-8-9-24-11-15)22(29)27(21(17)28)14-5-2-4-13(23)10-14/h2-7,10,12,15,24H,8-9,11H2,1H3/t15-/m1/s1
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n/an/a 31n/an/an/an/an/an/a



vTv Therapeutics LLC

US Patent


Assay Description
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...


US Patent US9393245 (2016)


BindingDB Entry DOI: 10.7270/Q2JH3K2T
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM65456
PNG
(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)
Show SMILES Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Show InChI InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
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n/an/a 33n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM76986
PNG
(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Show SMILES Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O
Show InChI InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)
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n/an/a 34n/an/an/an/an/an/a



Celgene Corporation

US Patent


Assay Description
The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...


US Patent US9694015 (2017)


BindingDB Entry DOI: 10.7270/Q2R49NZN
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM44245
PNG
(2-[(4E)-1-(1,3-benzothiazol-2-yl)-4-[1-(4-chloroan...)
Show SMILES COC(=O)Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C(C)=Nc1ccc(Cl)cc1
Show InChI InChI=1S/C21H17ClN4O3S/c1-12(23-14-9-7-13(22)8-10-14)19-16(11-18(27)29-2)25-26(20(19)28)21-24-15-5-3-4-6-17(15)30-21/h3-10,25H,11H2,1-2H3
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n/an/a 36.9n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM52783
PNG
(2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benzothiazo...)
Show SMILES COC(=O)Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C(C)=Nc1ccccc1
Show InChI InChI=1S/C21H18N4O3S/c1-13(22-14-8-4-3-5-9-14)19-16(12-18(26)28-2)24-25(20(19)27)21-23-15-10-6-7-11-17(15)29-21/h3-11,24H,12H2,1-2H3
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n/an/a 37.3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM54367
PNG
(2-[(4E)-1-(1,3-benzothiazol-2-yl)-4-[1-(4-methoxya...)
Show SMILES COC(=O)Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C(C)=Nc1ccc(OC)cc1
Show InChI InChI=1S/C22H20N4O4S/c1-13(23-14-8-10-15(29-2)11-9-14)20-17(12-19(27)30-3)25-26(21(20)28)22-24-16-6-4-5-7-18(16)31-22/h4-11,25H,12H2,1-3H3
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n/an/a<39.1n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM54393
PNG
(2,2-dimethyl-N-[N'-(5-methyl-1,3-benzoxazol-2-yl)a...)
Show SMILES Cc1ccc2oc(N=C(N)NC(=O)C(C)(C)C)nc2c1
Show InChI InChI=1S/C14H18N4O2/c1-8-5-6-10-9(7-8)16-13(20-10)18-12(15)17-11(19)14(2,3)4/h5-7H,1-4H3,(H3,15,16,17,18,19)
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n/an/a<39.1n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM62278
PNG
(2-bromobenzoic acid [2-[1-(2-methoxyethyl)-2,5-dim...)
Show SMILES COCCn1c(C)cc(C(=O)COC(=O)c2ccccc2Br)c1C
Show InChI InChI=1S/C18H20BrNO4/c1-12-10-15(13(2)20(12)8-9-23-3)17(21)11-24-18(22)14-6-4-5-7-16(14)19/h4-7,10H,8-9,11H2,1-3H3
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n/an/a<39.1n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
Tumor necrosis factor (TNF-alpha)


(Homo sapiens (Human))
BDBM62279
PNG
(2-hydroxybenzoic acid [2-[2,5-dimethyl-1-(2-thenyl...)
Show SMILES Cc1cc(C(=O)COC(=O)c2ccccc2O)c(C)n1Cc1cccs1
Show InChI InChI=1S/C20H19NO4S/c1-13-10-17(14(2)21(13)11-15-6-5-9-26-15)19(23)12-25-20(24)16-7-3-4-8-18(16)22/h3-10,22H,11-12H2,1-2H3
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n/an/a<39.1n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PR7TDC
More data for this
Ligand-Target Pair
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