Compile Data Set for Download or QSAR
maximum 50k data
Found 537 of ic50 data for polymerid = 5672,995
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526793(CHEMBL4562323)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  1.30nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human CDK7 incubated for 180 mins by LanthaScreen Eu Kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50:  3.20nMAssay Description:Competitive inhibition of human CDK7 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593925(CHEMBL5196685)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of CDK7 (unknown origin) incubated for 180 mins by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609501(CHEMBL5288241)
Affinity DataIC50:  4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609501(CHEMBL5288241)
Affinity DataIC50:  4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of full-length recombinant human His-tagged CDK7 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642790(US11857552, Compound APPAMP-004)
Affinity DataIC50:  4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642790(US11857552, Compound APPAMP-004)
Affinity DataIC50:  4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642790(US11857552, Compound APPAMP-004)
Affinity DataIC50:  4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526793(CHEMBL4562323)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin) in presence of ATP incubated for 1 hr by FRET based envision plate reader methodMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526793(CHEMBL4562323)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDk7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK7 (unknown origin) expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609503(CHEMBL5269885)
Affinity DataIC50:  5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50539722(CHEMBL4644572)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526799(CHEMBL4440386)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526792(CHEMBL4454044)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526792(CHEMBL4454044)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526798(CHEMBL4552441)
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609500(CHEMBL5286683)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609504(CHEMBL5274920)
Affinity DataIC50:  7nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526803(CHEMBL4434871 | US10870651, Compound 101)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642789(US11857552, Compound APPAMP-003)
Affinity DataIC50:  8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642789(US11857552, Compound APPAMP-003)
Affinity DataIC50:  8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642789(US11857552, Compound APPAMP-003)
Affinity DataIC50:  8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50378657(CHEMBL1230607)
Affinity DataIC50:  10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails DrugBank

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50: <10nMAssay Description:Inhibition of full-length recombinant human His-tagged CDK7 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM12116(3-(Indol-2-yl)indazole 6 | 3-[5-(morpholin-4-ylmet...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM444563(US10662186, Compound 82 | US10988476, Compound I-8...)
Affinity DataIC50:  11.4nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM444563(US10662186, Compound 82 | US10988476, Compound I-8...)
Affinity DataIC50:  11.4nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM478948(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl...)
Affinity DataIC50:  12nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642787(US11857552, Compound APPAMP-001)
Affinity DataIC50:  13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642787(US11857552, Compound APPAMP-001)
Affinity DataIC50:  13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM642787(US11857552, Compound APPAMP-001)
Affinity DataIC50:  13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526794(CHEMBL4303287 | US10787436, Compound I-18)
Affinity DataIC50:  14nMAssay Description:Inhibition of CDK7 (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50539720(CHEMBL4648392)
Affinity DataIC50: <15nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM601954(8'-methyl-2'-((4-((4-methylpiperazin- 1-yl)sulfony...)
Affinity DataIC50:  16nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM444565(US10662186, Compound 84 | US10988476, Compound I-8...)
Affinity DataIC50:  16.7nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM444565(US10662186, Compound 84 | US10988476, Compound I-8...)
Affinity DataIC50:  16.7nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593926(CHEMBL5207274)
Affinity DataIC50:  17nMAssay Description:Inhibition of CDK7 (unknown origin) using 5-FAM-tagged YSPTSPSYSPTSPSYSPTSPSKKKK peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50539718(CHEMBL4643708)
Affinity DataIC50:  18nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50609502(CHEMBL5273413)
Affinity DataIC50:  19nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50186373(CHEMBL424696 | N-(5-(2-(cyclohexyloxy)pyrimidin-4-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50526801(CHEMBL4474655)
Affinity DataIC50: <20nMAssay Description:Inhibition of CDK7 (unknown origin) after 4 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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