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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM199250(US9221808, 1bo | US9221808, 1bo-HCl | US9221808, 1...)

IC50: 16nMAssay Description:Inhibition of MLCK1 (unknown origin)More data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3040(23-(3-aminopropyl)-3-methyl-3,13,23-triazahexacycl...)

IC50: 18nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)

IC50: 22nMAssay Description:Inhibition of Myosin light chain kinase 1 (MLCK1)More data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50118955(CHEMBL94678 | Compound K-252a(epi))

IC50: 25nMAssay Description:Inhibition of Myosin light chain kinase 1 (MLCK1)More data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3035(3-{7,19-dihydroxy-23-methyl-14-oxo-3,13,23-triazah...)

IC50: 30nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50284317(3-(9-methoxy-13-methyl-5,7-dioxo-6,7,12,13-tetrahy...)

IC50: 32nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)

IC50: 43.2nMAssay Description:Inhibition of human MLCK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3045(3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...)

IC50: 49nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)

IC50: 51.3nMAssay Description:Inhibition of human MLCK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)

IC50: 55nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3048(23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...)

IC50: 120nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50284318(13-(3-dimethylamino-2-hydroxypropyl)-3-methoxy-12-...)

IC50: 120nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)

IC50: 170nMAssay Description:Inhibition of MLCK by HTRF assayMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3046(3-{7,19-dimethoxy-23-methyl-12,14-dioxo-3,13,23-tr...)

IC50: 180nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3044(3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazah...)

IC50: 200nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3037(23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...)

IC50: 220nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3039(23-[3-(dimethylamino)propyl]-3-methyl-3,13,23-tria...)

IC50: 250nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50590939(CHEMBL5174830)

IC50: 265nMAssay Description:Inhibition of MYLK in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3038(23-[3-(dimethylamino)propyl]-7,19-dihydroxy-3,13,2...)

IC50: 310nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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PDB MMDB Reactome pathway KEGG
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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50585045(CHEMBL5093741)

IC50: 334nMAssay Description:Inhibition of MYLK (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3036(23-[3-(dimethylamino)propyl]-3,13,23-triazahexacyc...)

IC50: 390nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50329498(CHEMBL1271447 | N-(6-benzyl-2-(phenethylamino)-5,6...)

IC50: 900nMAssay Description:Inhibition of MLCKMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3034(3-{7,19-dimethoxy-23-methyl-14-oxo-3,13,23-triazah...)

IC50: 1.60E+3nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)

IC50: 1.90E+3nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase (mMLCK)More data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)

IC50: 2.02E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120619(CHEMBL3618287)

IC50: 2.04E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120606(CHEMBL3618288)

IC50: 2.04E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120591(CHEMBL3618297)

IC50: 2.10E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120620(CHEMBL3618286)

IC50: 2.14E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120590(CHEMBL3618296)

IC50: 2.17E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120592(CHEMBL3618298)

IC50: 3.04E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)

IC50: 3.60E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120615(CHEMBL3618290)

IC50: 3.67E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120594(CHEMBL3618300)

IC50: 3.67E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50375647(CHEMBL541401)

IC50: 3.70E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50430289(CHEMBL2333445)

IC50: 4.00E+3nMAssay Description:Inhibition of MLCK (unknown origin) using [gamma-33P]ATPMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120614(CHEMBL551014)

IC50: 4.10E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120587(CHEMBL3618285)

IC50: 4.21E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120585(CHEMBL3618284)

IC50: 4.30E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120607(CHEMBL3618289)

IC50: 4.37E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120588(CHEMBL3618294)

IC50: 4.70E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)

IC50: 5.00E+3nMAssay Description:Inhibition of SmMLCK in the presence of 50uM ATPMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120611(CHEMBL558858)

IC50: 5.10E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3041(23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...)

IC50: 5.50E+3nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM3033(3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...)

IC50: 5.80E+3nMAssay Description:Tested for inhibition of Myosin light chain kinase from chicken gizzardMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120589(CHEMBL3618295)

IC50: 5.90E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120584(CHEMBL3618283)

IC50: 7.30E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120593(CHEMBL3618299)

IC50: 7.37E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Tumor Biology Center

BDBM50120612(CHEMBL563385)

IC50: 7.40E+3nMAssay Description:Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair