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Compile Data Set for Download or QSAR

Found 16 hits of ic50 data for polymerid = 5785   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106707
PNG
(CHEMBL1957358 | US8586620, 67)
Show SMILES CCSC(N)=Nc1ccc2[nH]cc(C3=CCN(C)CC3)c2c1
Show InChI InChI=1S/C17H22N4S/c1-3-22-17(18)20-13-4-5-16-14(10-13)15(11-19-16)12-6-8-21(2)9-7-12/h4-6,10-11,19H,3,7-9H2,1-2H3,(H2,18,20)
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n/an/a 48n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106699
PNG
(CHEMBL1957350 | US8586620, 46)
Show SMILES CN1CCC(=CC1)c1c[nH]c2ccc(cc12)N=C(N)c1ccco1
Show InChI InChI=1S/C19H20N4O/c1-23-8-6-13(7-9-23)16-12-21-17-5-4-14(11-15(16)17)22-19(20)18-3-2-10-24-18/h2-6,10-12,21H,7-9H2,1H3,(H2,20,22)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106698
PNG
(CHEMBL1957349 | US8586620, 42)
Show SMILES CN1CCC(=CC1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C19H20N4S/c1-23-8-6-13(7-9-23)16-12-21-17-5-4-14(11-15(16)17)22-19(20)18-3-2-10-24-18/h2-6,10-12,21H,7-9H2,1H3,(H2,20,22)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106706
PNG
(CHEMBL1957356 | US8586620, 64)
Show SMILES CN1CCC(=CC1)c1c[nH]c2ccc(NC(=S)NC(=O)c3ccccc3)cc12
Show InChI InChI=1S/C22H22N4OS/c1-26-11-9-15(10-12-26)19-14-23-20-8-7-17(13-18(19)20)24-22(28)25-21(27)16-5-3-2-4-6-16/h2-9,13-14,23H,10-12H2,1H3,(H2,24,25,27,28)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM50005835
PNG
((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Show SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3
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n/an/a 59n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106715
PNG
(US8586620, 97)
Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C19H22N4S/c1-23-8-2-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19(20)18-5-3-9-24-18/h3,5-7,9,11-12,15,21H,2,4,8,10H2,1H3,(H2,20,22)/t15-/m1/s1
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106701
PNG
(CHEMBL1957352 | US8586620, 51)
Show SMILES CN1CCC(=CC1)c1c[nH]c2ccc(CN=C(N)c3cccs3)cc12
Show InChI InChI=1S/C20H22N4S/c1-24-8-6-15(7-9-24)17-13-22-18-5-4-14(11-16(17)18)12-23-20(21)19-3-2-10-25-19/h2-6,10-11,13,22H,7-9,12H2,1H3,(H2,21,23)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106700
PNG
(CHEMBL1957354 | US8586620, 47)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(cc12)N=C(N)c1ccco1
Show InChI InChI=1S/C19H22N4O/c1-23-8-6-13(7-9-23)16-12-21-17-5-4-14(11-15(16)17)22-19(20)18-3-2-10-24-18/h2-5,10-13,21H,6-9H2,1H3,(H2,20,22)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106704
PNG
(US8586620, 59)
Show SMILES CN(C)CCc1c[nH]c2ccc(CN=C(N)c3cccs3)cc12
Show InChI InChI=1S/C18H22N4S/c1-22(2)8-7-14-12-20-16-6-5-13(10-15(14)16)11-21-18(19)17-4-3-9-23-17/h3-6,9-10,12,20H,7-8,11H2,1-2H3,(H2,19,21)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106720
PNG
(US8586620, 110)
Show SMILES CN1CCC(C1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C18H20N4S/c1-22-7-6-12(11-22)15-10-20-16-5-4-13(9-14(15)16)21-18(19)17-3-2-8-23-17/h2-5,8-10,12,20H,6-7,11H2,1H3,(H2,19,21)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106696
PNG
(US8586620, 56)
Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C17H20N4S/c1-21(2)8-7-12-11-19-15-6-5-13(10-14(12)15)20-17(18)16-4-3-9-22-16/h3-6,9-11,19H,7-8H2,1-2H3,(H2,18,20)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106721
PNG
(US8586620, 111)
Show SMILES CN1CCC(C1)c1c[nH]c2ccc(cc12)N=C(N)c1ccco1
Show InChI InChI=1S/C18H20N4O/c1-22-7-6-12(11-22)15-10-20-16-5-4-13(9-14(15)16)21-18(19)17-3-2-8-23-17/h2-5,8-10,12,20H,6-7,11H2,1H3,(H2,19,21)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106697
PNG
(CHEMBL1957353 | US8586620, 43)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C19H22N4S/c1-23-8-6-13(7-9-23)16-12-21-17-5-4-14(11-15(16)17)22-19(20)18-3-2-10-24-18/h2-5,10-13,21H,6-9H2,1H3,(H2,20,22)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106705
PNG
(US8586620, 62)
Show SMILES CCN1CCC(CC1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C20H24N4S/c1-2-24-9-7-14(8-10-24)17-13-22-18-6-5-15(12-16(17)18)23-20(21)19-4-3-11-25-19/h3-6,11-14,22H,2,7-10H2,1H3,(H2,21,23)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106703
PNG
(US8586620, 15)
Show SMILES CN(C)CCCc1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C18H22N4S/c1-22(2)9-3-5-13-12-20-16-8-7-14(11-15(13)16)21-18(19)17-6-4-10-23-17/h4,6-8,10-12,20H,3,5,9H2,1-2H3,(H2,19,21)
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair
5-hydroxytryptamine 1D receptor (5HT1D)


(Bos taurus (Bovine))
BDBM106717
PNG
(US8586620, 105)
Show SMILES CN1CCC[C@H]1Cc1c[nH]c2ccc(cc12)N=C(N)c1cccs1
Show InChI InChI=1S/C19H22N4S/c1-23-8-2-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19(20)18-5-3-9-24-18/h3,5-7,9,11-12,15,21H,2,4,8,10H2,1H3,(H2,20,22)/t15-/m0/s1
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NeurAxon, Inc.

US Patent


Assay Description
5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...


US Patent US8586620 (2013)


BindingDB Entry DOI: 10.7270/Q2348J0K
More data for this
Ligand-Target Pair