BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 67 hits of ic50 for UniProtKB: P00525   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Src


(Avian sarcoma virus)
BDBM3354
PNG
(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Show SMILES CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12
Show InChI InChI=1S/C22H22N4O2Se2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4007
PNG
(1 H-indole-3-alkanamide deriv. 10p | 2,2 -Dithiobi...)
Show SMILES CC(=O)NC(Cc1c(SSc2[nH]c3ccccc3c2CC(NC(C)=O)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C40H40N6O4S2/c1-25(47)43-35(37(49)41-23-27-13-5-3-6-14-27)21-31-29-17-9-11-19-33(29)45-39(31)51-52-40-32(30-18-10-12-20-34(30)46-40)22-36(44-26(2)48)38(50)42-24-28-15-7-4-8-16-28/h3-20,35-36,45-46H,21-24H2,1-2H3,(H,41,49)(H,42,50)(H,43,47)(H,44,48)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4020
PNG
(2-{[4-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-...)
Show SMILES CC(=O)Oc1cccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4c(OC(C)=O)cccc4n3C)c(C(=O)Nc3ccccc3)c12
Show InChI InChI=1S/C36H30N4O6S2/c1-21(41)45-27-19-11-17-25-29(27)31(33(43)37-23-13-7-5-8-14-23)35(39(25)3)47-48-36-32(34(44)38-24-15-9-6-10-16-24)30-26(40(36)4)18-12-20-28(30)46-22(2)42/h5-20H,1-4H3,(H,37,43)(H,38,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 650n/an/an/an/a7.525



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4008
PNG
(1 H-indole-3-alkanamide deriv. 10q | 2,2-Dithiobis...)
Show SMILES FC(F)(F)C(=O)NC(Cc1c(SSc2[nH]c3ccccc3c2CC(NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C40H34F6N6O4S2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3997
PNG
(1 H-indole-3-alkanamide deriv. 10f | N-methyl-3-[2...)
Show SMILES CNC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NC)[nH]c2ccccc12
Show InChI InChI=1S/C24H26N4O2S2/c1-25-21(29)13-11-17-15-7-3-5-9-19(15)27-23(17)31-32-24-18(12-14-22(30)26-2)16-8-4-6-10-20(16)28-24/h3-10,27-28H,11-14H2,1-2H3,(H,25,29)(H,26,30)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 750n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3999
PNG
(1 H-indole-3-alkanamide deriv. 10h | 3-[2-({3-[2-(...)
Show SMILES CN(C)C(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)N(C)C)[nH]c2ccccc12
Show InChI InChI=1S/C26H30N4O2S2/c1-29(2)23(31)15-13-19-17-9-5-7-11-21(17)27-25(19)33-34-26-20(14-16-24(32)30(3)4)18-10-6-8-12-22(18)28-26/h5-12,27-28H,13-16H2,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4012
PNG
(1 H-indole-3-alkanamide deriv. 10u | N-benzyl-4-[2...)
Show SMILES O=C(CCCc1c(SSc2[nH]c3ccccc3c2CCCC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1
Show InChI InChI=1S/C38H38N4O2S2/c43-35(39-25-27-13-3-1-4-14-27)23-11-19-31-29-17-7-9-21-33(29)41-37(31)45-46-38-32(30-18-8-10-22-34(30)42-38)20-12-24-36(44)40-26-28-15-5-2-6-16-28/h1-10,13-18,21-22,41-42H,11-12,19-20,23-26H2,(H,39,43)(H,40,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3352
PNG
(2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...)
Show SMILES Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc12
Show InChI InChI=1S/C28H32N2O4Se2/c1-27(2,3)33-25(31)21-17-13-9-11-15-19(17)29(7)23(21)35-36-24-22(26(32)34-28(4,5)6)18-14-10-12-16-20(18)30(24)8/h9-16H,1-8H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4003
PNG
(1 H-indole-3-alkanamide deriv. 10l | 2,2 -Dithiobi...)
Show SMILES OC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(cc3)C(O)=O)[nH]c3ccccc23)cc1
Show InChI InChI=1S/C38H34N4O6S2/c43-33(39-21-23-9-13-25(14-10-23)37(45)46)19-17-29-27-5-1-3-7-31(27)41-35(29)49-50-36-30(28-6-2-4-8-32(28)42-36)18-20-34(44)40-22-24-11-15-26(16-12-24)38(47)48/h1-16,41-42H,17-22H2,(H,39,43)(H,40,44)(H,45,46)(H,47,48)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3996
PNG
(1 H-indole-3-alkanamide deriv. 10e | 2,2 -Dithiobi...)
Show SMILES NC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(N)=O)[nH]c2ccccc12
Show InChI InChI=1S/C22H22N4O2S2/c23-19(27)11-9-15-13-5-1-3-7-17(13)25-21(15)29-30-22-16(10-12-20(24)28)14-6-2-4-8-18(14)26-22/h1-8,25-26H,9-12H2,(H2,23,27)(H2,24,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3351
PNG
(2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl...)
Show SMILES NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3351
PNG
(2-amino-3-[2-({3-[2-amino-2-(benzylcarbamoyl)ethyl...)
Show SMILES NC(Cc1c(SSc2[nH]c3ccccc3c2CC(N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H36N6O2S2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3358
PNG
(1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...)
Show SMILES CCN(CC)CCn1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2CCN(CC)CC)c(C(=O)NC)c2ccccc12
Show InChI InChI=1S/C32H44N6O2Se2/c1-7-35(8-2)19-21-37-25-17-13-11-15-23(25)27(29(39)33-5)31(37)41-42-32-28(30(40)34-6)24-16-12-14-18-26(24)38(32)22-20-36(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4002
PNG
(1 H-indole-3-alkanamide deriv. 10k | 2,2 -dithiobi...)
Show SMILES COC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(cc3)C(=O)OC)[nH]c3ccccc23)cc1
Show InChI InChI=1S/C40H38N4O6S2/c1-49-39(47)27-15-11-25(12-16-27)23-41-35(45)21-19-31-29-7-3-5-9-33(29)43-37(31)51-52-38-32(30-8-4-6-10-34(30)44-38)20-22-36(46)42-24-26-13-17-28(18-14-26)40(48)50-2/h3-18,43-44H,19-24H2,1-2H3,(H,41,45)(H,42,46)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3355
PNG
(2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1-methy...)
Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2c(C(=O)NCCN(CC)CC)c3ccccc3n2C)n(C)c2ccccc12
Show InChI InChI=1S/C32H44N6O2Se2/c1-7-37(8-2)21-19-33-29(39)27-23-15-11-13-17-25(23)35(5)31(27)41-42-32-28(24-16-12-14-18-26(24)36(32)6)30(40)34-20-22-38(9-3)10-4/h11-18H,7-10,19-22H2,1-6H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3361
PNG
((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...)
Show SMILES N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4014
PNG
(1 H-indole-3-alkanamide deriv. 11e | 2,3-Dihydro-2...)
Show SMILES NC(=O)CCC1C(=S)Nc2ccccc12
Show InChI InChI=1S/C11H12N2OS/c12-10(14)6-5-8-7-3-1-2-4-9(7)13-11(8)15/h1-4,8H,5-6H2,(H2,12,14)(H,13,15)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3353
PNG
(2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic a...)
Show SMILES Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12
Show InChI InChI=1S/C20H16N2O4Se2/c1-21-13-9-5-3-7-11(13)15(19(23)24)17(21)27-28-18-16(20(25)26)12-8-4-6-10-14(12)22(18)2/h3-10H,1-2H3,(H,23,24)(H,25,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3991
PNG
(1 H-indole-3-alkanamide deriv. 10b | 2-(2-{[3-(cya...)
Show SMILES N#CCc1c(SSc2[nH]c3ccccc3c2CC#N)[nH]c2ccccc12
Show InChI InChI=1S/C20H14N4S2/c21-11-9-15-13-5-1-3-7-17(13)23-19(15)25-26-20-16(10-12-22)14-6-2-4-8-18(14)24-20/h1-8,23-24H,9-10H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3356
PNG
(2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...)
Show SMILES CNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NC)[nH]c2ccccc12
Show InChI InChI=1S/C20H18N4O2Se2/c1-21-17(25)15-11-7-3-5-9-13(11)23-19(15)27-28-20-16(18(26)22-2)12-8-4-6-10-14(12)24-20/h3-10,23-24H,1-2H3,(H,21,25)(H,22,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3998
PNG
(1 H-indole-3-alkanamide deriv. 10g | N-methoxy-3-[...)
Show SMILES CONC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NOC)[nH]c2ccccc12
Show InChI InChI=1S/C24H26N4O4S2/c1-31-27-21(29)13-11-17-15-7-3-5-9-19(15)25-23(17)33-34-24-18(12-14-22(30)28-32-2)16-8-4-6-10-20(16)26-24/h3-10,25-26H,11-14H2,1-2H3,(H,27,29)(H,28,30)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4001
PNG
(1 H-indole-3-alkanamide deriv. 10j | N-benzyl-3-[2...)
Show SMILES O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1
Show InChI InChI=1S/C36H34N4O2S2/c41-33(37-23-25-11-3-1-4-12-25)21-19-29-27-15-7-9-17-31(27)39-35(29)43-44-36-30(28-16-8-10-18-32(28)40-36)20-22-34(42)38-24-26-13-5-2-6-14-26/h1-18,39-40H,19-24H2,(H,37,41)(H,38,42)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4016
PNG
(1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-1H-indol...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3ccccc3n2C)c(C(=O)Nc2ccccc2)c2ccccc12
Show InChI InChI=1S/C32H26N4O2S2/c1-35-25-19-11-9-17-23(25)27(29(37)33-21-13-5-3-6-14-21)31(35)39-40-32-28(24-18-10-12-20-26(24)36(32)2)30(38)34-22-15-7-4-8-16-22/h3-20H,1-2H3,(H,33,37)(H,34,38)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.20E+3n/an/an/an/a7.525



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4013
PNG
(1 H-indole-3-alkanamide deriv. 11a | N-benzyl-2-(2...)
Show SMILES O=C(CC1C(=S)Nc2ccccc12)NCc1ccccc1
Show InChI InChI=1S/C17H16N2OS/c20-16(18-11-12-6-2-1-3-7-12)10-14-13-8-4-5-9-15(13)19-17(14)21/h1-9,14H,10-11H2,(H,18,20)(H,19,21)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4034
PNG
(2-{[6-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-...)
Show SMILES CC(=O)Oc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(OC(C)=O)cc4n3C)n(C)c2c1
Show InChI InChI=1S/C36H30N4O6S2/c1-21(41)45-25-15-17-27-29(19-25)39(3)35(31(27)33(43)37-23-11-7-5-8-12-23)47-48-36-32(34(44)38-24-13-9-6-10-14-24)28-18-16-26(46-22(2)42)20-30(28)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3981
PNG
(1 H-indole-3-alkanamide deriv. 7 | Dimethyl 2,2 -D...)
Show SMILES COC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)OC)[nH]c2ccccc12
Show InChI InChI=1S/C24H24N2O4S2/c1-29-21(27)13-11-17-15-7-3-5-9-19(15)25-23(17)31-32-24-18(12-14-22(28)30-2)16-8-4-6-10-20(16)26-24/h3-10,25-26H,11-14H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4038
PNG
(7-methoxy-2-{[7-methoxy-1-methyl-3-(phenylcarbamoy...)
Show SMILES COc1cccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4cccc(OC)c4n3C)n(C)c12
Show InChI InChI=1S/C34H30N4O4S2/c1-37-29-23(17-11-19-25(29)41-3)27(31(39)35-21-13-7-5-8-14-21)33(37)43-44-34-28(32(40)36-22-15-9-6-10-16-22)24-18-12-20-26(42-4)30(24)38(34)2/h5-20H,1-4H3,(H,35,39)(H,36,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4033
PNG
(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Show SMILES COc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(OC)cc4n3C)n(C)c2c1
Show InChI InChI=1S/C34H30N4O4S2/c1-37-27-19-23(41-3)15-17-25(27)29(31(39)35-21-11-7-5-8-12-21)33(37)43-44-34-30(32(40)36-22-13-9-6-10-14-22)26-18-16-24(42-4)20-28(26)38(34)2/h5-20H,1-4H3,(H,35,39)(H,36,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3357
PNG
(2,2 -Diselenobis[N-[2-(diethylamino)ethyl]-1H-indo...)
Show SMILES CCN(CC)CCNC(=O)c1c([Se][Se]c2[nH]c3ccccc3c2C(=O)NCCN(CC)CC)[nH]c2ccccc12
Show InChI InChI=1S/C30H40N6O2Se2/c1-5-35(6-2)19-17-31-27(37)25-21-13-9-11-15-23(21)33-29(25)39-40-30-26(22-14-10-12-16-24(22)34-30)28(38)32-18-20-36(7-3)8-4/h9-16,33-34H,5-8,17-20H2,1-4H3,(H,31,37)(H,32,38)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3990
PNG
(1 H-indole-3-alkanamide deriv. 10a | N-benzyl-2-[2...)
Show SMILES O=C(Cc1c(SSc2[nH]c3ccccc3c2CC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1
Show InChI InChI=1S/C34H30N4O2S2/c39-31(35-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)37-33(27)41-42-34-28(26-16-8-10-18-30(26)38-34)20-32(40)36-22-24-13-5-2-6-14-24/h1-18,37-38H,19-22H2,(H,35,39)(H,36,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3362
PNG
((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...)
Show SMILES N[C@@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@H](N)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H36N6O2Se2/c37-29(33(43)39-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-31(25)41-35(27)45-46-36-28(26-16-8-10-18-32(26)42-36)20-30(38)34(44)40-22-24-13-5-2-6-14-24/h1-18,29-30,41-42H,19-22,37-38H2,(H,39,43)(H,40,44)/t29-,30-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4027
PNG
(2,2 -Dithiobis( 5-hydroxy- 1-methyl-N-phenylindole...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(O)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(O)ccc12
Show InChI InChI=1S/C32H26N4O4S2/c1-35-25-15-13-21(37)17-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)41-42-32-28(30(40)34-20-11-7-4-8-12-20)24-18-22(38)14-16-26(24)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4000
PNG
(1 H-indole-3-alkanamide deriv. 10i | 2,2-Dithiobis...)
Show SMILES O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)Nc2ccccc2)[nH]c2ccccc12)Nc1ccccc1
Show InChI InChI=1S/C34H30N4O2S2/c39-31(35-23-11-3-1-4-12-23)21-19-27-25-15-7-9-17-29(25)37-33(27)41-42-34-28(26-16-8-10-18-30(26)38-34)20-22-32(40)36-24-13-5-2-6-14-24/h1-18,37-38H,19-22H2,(H,35,39)(H,36,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4029
PNG
(5-cyano-2-{[5-cyano-1-methyl-3-(phenylcarbamoyl)-1...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)C#N)c(C(=O)Nc2ccccc2)c2cc(ccc12)C#N
Show InChI InChI=1S/C34H24N6O2S2/c1-39-27-15-13-21(19-35)17-25(27)29(31(41)37-23-9-5-3-6-10-23)33(39)43-44-34-30(32(42)38-24-11-7-4-8-12-24)26-18-22(20-36)14-16-28(26)40(34)2/h3-18H,1-2H3,(H,37,41)(H,38,42)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4035
PNG
(6-hydroxy-2-{[6-hydroxy-1-methyl-3-(phenylcarbamoy...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3ccc(O)cc3n2C)c(C(=O)Nc2ccccc2)c2ccc(O)cc12
Show InChI InChI=1S/C32H26N4O4S2/c1-35-25-17-21(37)13-15-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)41-42-32-28(30(40)34-20-11-7-4-8-12-20)24-16-14-22(38)18-26(24)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4041
PNG
(1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-1H-pyrro...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cccnc3n2C)c(C(=O)Nc2ccccc2)c2cccnc12
Show InChI InChI=1S/C30H24N6O2S2/c1-35-25-21(15-9-17-31-25)23(27(37)33-19-11-5-3-6-12-19)29(35)39-40-30-24(22-16-10-18-32-26(22)36(30)2)28(38)34-20-13-7-4-8-14-20/h3-18H,1-2H3,(H,33,37)(H,34,38)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4028
PNG
(1-methyl-2-{[1-methyl-3-(phenylcarbamoyl)-5-(trifl...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)C(F)(F)F)c(C(=O)Nc2ccccc2)c2cc(ccc12)C(F)(F)F
Show InChI InChI=1S/C34H24F6N4O2S2/c1-43-25-15-13-19(33(35,36)37)17-23(25)27(29(45)41-21-9-5-3-6-10-21)31(43)47-48-32-28(30(46)42-22-11-7-4-8-12-22)24-18-20(34(38,39)40)14-16-26(24)44(32)2/h3-18H,1-2H3,(H,41,45)(H,42,46)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4021
PNG
(5-fluoro-2-{[5-fluoro-1-methyl-3-(phenylcarbamoyl)...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(F)ccc3n2C)c(C(=O)Nc2ccccc2)c2cc(F)ccc12
Show InChI InChI=1S/C32H24F2N4O2S2/c1-37-25-15-13-19(33)17-23(25)27(29(39)35-21-9-5-3-6-10-21)31(37)41-42-32-28(30(40)36-22-11-7-4-8-12-22)24-18-20(34)14-16-26(24)38(32)2/h3-18H,1-2H3,(H,35,39)(H,36,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.00E+3n/an/an/an/a7.525



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3360
PNG
((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C40H34F6N6O4Se2/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-58-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.20E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3350
PNG
(CHEMBL342929 | N,1-dimethyl-2-{[1-methyl-3-(methyl...)
Show SMILES CNC(=O)c1c(SSc2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12
Show InChI InChI=1S/C22H22N4O2S2/c1-23-19(27)17-13-9-5-7-11-15(13)25(3)21(17)29-30-22-18(20(28)24-2)14-10-6-8-12-16(14)26(22)4/h5-12H,1-4H3,(H,23,27)(H,24,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.70E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4030
PNG
(1-methyl-2-{[1-methyl-5-nitro-3-(phenylcarbamoyl)-...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cc(ccc3n2C)[N+]([O-])=O)c(C(=O)Nc2ccccc2)c2cc(ccc12)[N+]([O-])=O
Show InChI InChI=1S/C32H24N6O6S2/c1-35-25-15-13-21(37(41)42)17-23(25)27(29(39)33-19-9-5-3-6-10-19)31(35)45-46-32-28(30(40)34-20-11-7-4-8-12-20)24-18-22(38(43)44)14-16-26(24)36(32)2/h3-18H,1-2H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4026
PNG
(2-{[5-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-...)
Show SMILES CC(=O)Oc1ccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4cc(OC(C)=O)ccc4n3C)c(C(=O)Nc3ccccc3)c2c1
Show InChI InChI=1S/C36H30N4O6S2/c1-21(41)45-25-15-17-29-27(19-25)31(33(43)37-23-11-7-5-8-12-23)35(39(29)3)47-48-36-32(34(44)38-24-13-9-6-10-14-24)28-20-26(46-22(2)42)16-18-30(28)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.70E+3n/an/an/an/a7.525



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4015
PNG
(1 H-indole-3-alkanamide deriv. 11j | N-benzyl-3-(2...)
Show SMILES O=C(CCC1C(=S)Nc2ccccc12)NCc1ccccc1
Show InChI InChI=1S/C18H18N2OS/c21-17(19-12-13-6-2-1-3-7-13)11-10-15-14-8-4-5-9-16(14)20-18(15)22/h1-9,15H,10-12H2,(H,19,21)(H,20,22)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.30E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4042
PNG
(1-methyl-N-phenyl-2-sulfanylidene-2,3-dihydro-1H-i...)
Show SMILES CN1C(=S)C(C(=O)Nc2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H14N2OS/c1-18-13-10-6-5-9-12(13)14(16(18)20)15(19)17-11-7-3-2-4-8-11/h2-10,14H,1H3,(H,17,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.70E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4039
PNG
(2-{[7-(acetyloxy)-1-methyl-3-(phenylcarbamoyl)-1H-...)
Show SMILES CC(=O)Oc1cccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4cccc(OC(C)=O)c4n3C)n(C)c12
Show InChI InChI=1S/C36H30N4O6S2/c1-21(41)45-27-19-11-17-25-29(33(43)37-23-13-7-5-8-14-23)35(39(3)31(25)27)47-48-36-30(34(44)38-24-15-9-6-10-16-24)26-18-12-20-28(46-22(2)42)32(26)40(36)4/h5-20H,1-4H3,(H,37,43)(H,38,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.11E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4006
PNG
(1 H-indole-3-alkanamide deriv. 10o | N-(2-phenylet...)
Show SMILES O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NCCc2ccccc2)[nH]c2ccccc12)NCCc1ccccc1
Show InChI InChI=1S/C38H38N4O2S2/c43-35(39-25-23-27-11-3-1-4-12-27)21-19-31-29-15-7-9-17-33(29)41-37(31)45-46-38-32(30-16-8-10-18-34(30)42-38)20-22-36(44)40-26-24-28-13-5-2-6-14-28/h1-18,41-42H,19-26H2,(H,39,43)(H,40,44)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 598-609 (1994)


Article DOI: 10.1021/jm00031a009
BindingDB Entry DOI: 10.7270/Q2MS3QZH
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4044
PNG
(1,3-dihydro-1-methyl-N-phenyl-2-thioxo-2H-pyrrolo[...)
Show SMILES CN1C(=S)C(C(=O)Nc2ccccc2)c2cccnc12
Show InChI InChI=1S/C15H13N3OS/c1-18-13-11(8-5-9-16-13)12(15(18)20)14(19)17-10-6-3-2-4-7-10/h2-9,12H,1H3,(H,17,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.07E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM3359
PNG
((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Show SMILES FC(F)(F)C(=O)N[C@H](Cc1c([Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C40H34F6N6O4Se/c41-39(42,43)37(55)51-31(33(53)47-21-23-11-3-1-4-12-23)19-27-25-15-7-9-17-29(25)49-35(27)57-36-28(26-16-8-10-18-30(26)50-36)20-32(52-38(56)40(44,45)46)34(54)48-22-24-13-5-2-6-14-24/h1-18,31-32,49-50H,19-22H2,(H,47,53)(H,48,54)(H,51,55)(H,52,56)/t31-,32-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 413-26 (1997)


Article DOI: 10.1021/jm960689b
BindingDB Entry DOI: 10.7270/Q2TH8JWJ
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4046
PNG
(1-Methyl-2-(methylthio)-N-phenyl-1H-indole-3-carbo...)
Show SMILES CSc1c(C(=O)Nc2ccccc2)c2ccccc2n1C
Show InChI InChI=1S/C17H16N2OS/c1-19-14-11-7-6-10-13(14)15(17(19)21-2)16(20)18-12-8-4-3-5-9-12/h3-11H,1-2H3,(H,18,20)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Src


(Avian sarcoma virus)
BDBM4040
PNG
(7-hydroxy-2-{[7-hydroxy-1-methyl-3-(phenylcarbamoy...)
Show SMILES Cn1c(SSc2c(C(=O)Nc3ccccc3)c3cccc(O)c3n2C)c(C(=O)Nc2ccccc2)c2cccc(O)c12
Show InChI InChI=1S/C32H26N4O4S2/c1-35-27-21(15-9-17-23(27)37)25(29(39)33-19-11-5-3-6-12-19)31(35)41-42-32-26(30(40)34-20-13-7-4-8-14-20)22-16-10-18-24(38)28(22)36(32)2/h3-18,37-38H,1-2H3,(H,33,39)(H,34,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 37: 2033-42 (1994)


Article DOI: 10.1021/jm00039a016
BindingDB Entry DOI: 10.7270/Q2H41PMC
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 67 total )  |  Next  |  Last  >>
Jump to: