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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P07147   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Mus musculus (Mouse))
BDBM152929
PNG
(US8993596, Compound 24)
Show SMILES C[C@H](NC(=O)N1CCC(CC1)c1ccc(O)cc1O)c1ccccc1
Show InChI InChI=1S/C20H24N2O3/c1-14(15-5-3-2-4-6-15)21-20(25)22-11-9-16(10-12-22)18-8-7-17(23)13-19(18)24/h2-8,13-14,16,23-24H,9-12H2,1H3,(H,21,25)/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



Galderma Research & Development

US Patent


Assay Description
The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...


US Patent US8993596 (2015)


BindingDB Entry DOI: 10.7270/Q2HD7TDC
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM152928
PNG
(US8993596, Compound 48)
Show SMILES O[C@H](C(=O)N1CCC(CC1)c1ccc(O)cc1O)c1ccccc1
Show InChI InChI=1S/C19H21NO4/c21-15-6-7-16(17(22)12-15)13-8-10-20(11-9-13)19(24)18(23)14-4-2-1-3-5-14/h1-7,12-13,18,21-23H,8-11H2/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/an/an/a



Galderma Research & Development

US Patent


Assay Description
The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...


US Patent US8993596 (2015)


BindingDB Entry DOI: 10.7270/Q2HD7TDC
More data for this
Ligand-Target Pair
Tyrosinase


(Mus musculus (Mouse))
BDBM50248158
PNG
(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Show SMILES CCCCc1ccc(O)cc1O
Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 3.00E+3n/an/an/an/an/an/a



Galderma Research & Development

US Patent


Assay Description
The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...


US Patent US8993596 (2015)


BindingDB Entry DOI: 10.7270/Q2HD7TDC
More data for this
Ligand-Target Pair