Compile Data Set for Download or QSAR
maximum 50k data
Found 124 of kd data for polymerid = 7505
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454969(US10730870, Example 138 | US10730870, Example 145 ...)
Affinity DataKd:  10nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). His-tagged VHL protein was immobilized on a carboxym...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581595(CHEMBL4215078)
Affinity DataKd:  34nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50459880(CHEMBL4226570)
Affinity DataKd:  34nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50586757(CHEMBL5089280)
Affinity DataKd:  45nMAssay Description:Binding affinity to VHL (unknown origin) assessed as displacement of HIF-1alpha by binary binding competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50459944(CHEMBL4225537)
Affinity DataKd:  58nMAssay Description:Displacement of FAM-labeled HIF-1alpha peptide from VCB (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581599(CHEMBL5087181)
Affinity DataKd:  63nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581597(CHEMBL5074720)
Affinity DataKd:  66nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50459944(CHEMBL4225537)
Affinity DataKd:  90nMAssay Description:Binding affinity to VHL (unknown origin)More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581596(CHEMBL5075400)
Affinity DataKd:  98nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50586758(CHEMBL5081978)
Affinity DataKd:  102nMAssay Description:Binding affinity to VHL (unknown origin) assessed as displacement of HIF-1alpha by binary binding competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataKd:  113nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581587(CHEMBL5087145)
Affinity DataKd:  119nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataKd:  120nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). His-tagged VHL protein was immobilized on a carboxym...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50586756(CHEMBL5089544)
Affinity DataKd:  125nMAssay Description:Binding affinity to VHL (unknown origin) assessed as displacement of HIF-1alpha by binary binding competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581588(CHEMBL5082521)
Affinity DataKd:  136nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581589(CHEMBL4793272)
Affinity DataKd:  138nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581601(CHEMBL5079045)
Affinity DataKd:  143nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581590(CHEMBL5081396)
Affinity DataKd:  144nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581592(CHEMBL5094871)
Affinity DataKd:  170nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581591(CHEMBL5087530)
Affinity DataKd:  170nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataKd:  185nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581593(CHEMBL5086047)
Affinity DataKd:  200nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581594(CHEMBL5086897)
Affinity DataKd:  200nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581600(CHEMBL5086339)
Affinity DataKd:  236nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454980(US10730870, Example 207)
Affinity DataKd:  240nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). His-tagged VHL protein was immobilized on a carboxym...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50581598(CHEMBL5081695)
Affinity DataKd:  246nMAssay Description:Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099055(CHEMBL3344088)
Affinity DataKd:  291nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454979(US10730870, Example 205)
Affinity DataKd:  330nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). His-tagged VHL protein was immobilized on a carboxym...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099058(CHEMBL3344084)
Affinity DataKd:  384nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454858(US10730870, Example 21 | US11512083, Example 21)
Affinity DataKd:  450nMAssay Description:Displacement of FAM-labeled HIF-1alpha peptide from VCB (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50246759(CHEMBL4098772)
Affinity DataKd:  500nMAssay Description:Binding affinity to VHL (unknown origin) assessed as reduction of HIF1alpha derived peptide binding to VHL complex by competitive binding fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099056(CHEMBL3344087)
Affinity DataKd:  588nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099060(CHEMBL3344083)
Affinity DataKd:  714nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50561318(CHEMBL4782620)
Affinity DataKd:  800nMAssay Description:Displacement of FAM-labeled HIF-1alpha peptide from VCB (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099061(CHEMBL3344082)
Affinity DataKd:  826nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099057(CHEMBL3344086)
Affinity DataKd:  943nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM621998(US20230312542, Example 54)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM621993(US20230312542, Example 44)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622021(US20230312542, Example 107)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622037(US20230312542, Example 159)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622036(US20230312542, Example 158)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622022(US20230312542, Example 108)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622023(US20230312542, Example 111)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622033(US20230312542, Example 153)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM622034(US20230312542, Example 154)
Affinity DataKd: <1.00E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099059(CHEMBL3344085)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50446139(CHEMBL3108882 | US10730870, Example 135 | US115120...)
Affinity DataKd:  1.50E+3nMAssay Description:Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099053(CHEMBL3344149)
Affinity DataKd:  2.04E+3nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099052(CHEMBL3344150)
Affinity DataKd:  2.32E+3nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50099144(CHEMBL3344079)
Affinity DataKd:  3.27E+3nMAssay Description:Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra...More data for this Ligand-Target Pair
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