TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))
G1 Therapeutics
US Patent
G1 Therapeutics
US Patent
Affinity DataIC50: 0.940nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2/cycE1 (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair