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Compile Data Set for Download or QSAR

Found 8 hits of ic50 data for polymerid = 8166   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193879
PNG
(2-[2-(2,4-Dichlorobenzyl)-6-nitro-1H-benzimidazol-...)
Show SMILES NNC(=O)Cn1c(Cc2ccc(Cl)cc2Cl)nc2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C16H13Cl2N5O3/c17-10-2-1-9(12(18)6-10)5-15-20-13-4-3-11(23(25)26)7-14(13)22(15)8-16(24)21-19/h1-4,6-7H,5,8,19H2,(H,21,24)
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Article
PubMed
n/an/a 1.05E+4n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
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UniChem

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Article
PubMed
n/an/a 1.33E+4n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193880
PNG
(5-{[2-(2,4-Dichlorobenzyl)-6-nitro-1H-benzimidazol...)
Show SMILES [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)cc3Cl)n(Cc3nnc(S)o3)c2c1
Show InChI InChI=1S/C17H11Cl2N5O3S/c18-10-2-1-9(12(19)6-10)5-15-20-13-4-3-11(24(25)26)7-14(13)23(15)8-16-21-22-17(28)27-16/h1-4,6-7H,5,8H2,(H,22,28)
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Article
PubMed
n/an/a 2.69E+4n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193882
PNG
(5-{[2-(2,4-Dichlorobenzyl)-7-nitro-1H-benzimidazol...)
Show SMILES [O-][N+](=O)c1cccc2nc(Cc3ccc(Cl)cc3Cl)n(Cc3nnc(S)n3-c3ccccc3)c12
Show InChI InChI=1S/C23H16Cl2N6O2S/c24-15-10-9-14(17(25)12-15)11-20-26-18-7-4-8-19(31(32)33)22(18)29(20)13-21-27-28-23(34)30(21)16-5-2-1-3-6-16/h1-10,12H,11,13H2,(H,28,34)
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Article
PubMed
n/an/a 4.05E+4n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193881
PNG
(2-{[2-(2,4-Dichlorobenzyl)-6-nitro-1H-benzimidazol...)
Show SMILES [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)cc3Cl)n(CC(=O)NNC(=S)Nc3ccccc3)c2c1
Show InChI InChI=1S/C23H18Cl2N6O3S/c24-15-7-6-14(18(25)11-15)10-21-27-19-9-8-17(31(33)34)12-20(19)30(21)13-22(32)28-29-23(35)26-16-4-2-1-3-5-16/h1-9,11-12H,10,13H2,(H,28,32)(H2,26,29,35)
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Article
PubMed
n/an/a 9.30E+4n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193874
PNG
(2-{[2-(2,4-Dichlorobenzyl)-1H-benzimidazol-1-yl]ac...)
Show SMILES Clc1ccc(Cc2nc3ccccc3n2CC(=O)NNC(=S)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C23H19Cl2N5OS/c24-16-11-10-15(18(25)13-16)12-21-27-19-8-4-5-9-20(19)30(21)14-22(31)28-29-23(32)26-17-6-2-1-3-7-17/h1-11,13H,12,14H2,(H,28,31)(H2,26,29,32)
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Article
PubMed
n/an/a 1.41E+5n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193876
PNG
(5-{[2-(2,4-Dichlorobenzyl)-1H-benzimidazol-1-yl]me...)
Show SMILES Clc1ccc(Cc2nc3ccccc3n2Cc2nnc(Nc3ccccc3)s2)c(Cl)c1
Show InChI InChI=1S/C23H17Cl2N5S/c24-16-11-10-15(18(25)13-16)12-21-27-19-8-4-5-9-20(19)30(21)14-22-28-29-23(31-22)26-17-6-2-1-3-7-17/h1-11,13H,12,14H2,(H,26,29)
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UniChem
Article
PubMed
n/an/a 1.58E+5n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-glucosidase)


(Saccharomyces cerevisiae (Yeast))
BDBM193873
PNG
(5-{[2-(2,4-Dichlorobenzyl)-1H-benzimidazol-1-yl]me...)
Show SMILES Sc1nnc(Cn2c(Cc3ccc(Cl)cc3Cl)nc3ccccc23)o1
Show InChI InChI=1S/C17H12Cl2N4OS/c18-11-6-5-10(12(19)8-11)7-15-20-13-3-1-2-4-14(13)23(15)9-16-21-22-17(25)24-16/h1-6,8H,7,9H2,(H,22,25)
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Article
PubMed
n/an/a 2.54E+5n/an/an/an/an/an/a



Recep Tayyip Erdogan University



Assay Description
α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...


Bioorg Chem 68: 226-35 (2016)


Article DOI: 10.1016/j.bioorg.2016.08.011
BindingDB Entry DOI: 10.7270/Q20C4TKG
More data for this
Ligand-Target Pair