Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ki data for polymerid = 9822
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of full length SIRT6 (unknown origin) using acetylated H3K9 peptide as substrate after 2 hrs in presence of NADMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  2.02E+3nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor in rat aortaMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  4.62E+3nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor in rat aortaMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50408840(CHEMBL5271662)
Affinity DataKi:  1.34E+4nMAssay Description:Antagonist activity at adrenergic alpha1A receptor in rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  4.50E+5nMAssay Description:Inhibition of human SIRT6 preincubated for 5 mins in presence of substrate followed enzyme addition measured after 5 to 10 mins in presence of NAD by...More data for this Ligand-Target Pair