Compile Data Set for Download or QSAR

Found 6 hits of ec50 data for complexid = 50000720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070076 (CHEMBL3407828) Show SMILES Cl.NC(=N)Nc1ccc2CCCCc2n1 Show InChI InChI=1S/C10H14N4.ClH/c11-10(12)14-9-6-5-7-3-1-2-4-8(7)13-9;/h5-6H,1-4H2,(H4,11,12,13,14);1H	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070101 (CHEMBL3407840) Show SMILES C1CN=C(Nc2ccc3CCCCc3n2)N1 Show InChI InChI=1S/C12H16N4/c1-2-4-10-9(3-1)5-6-11(15-10)16-12-13-7-8-14-12/h5-6H,1-4,7-8H2,(H2,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.57E+3	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070100 (CHEMBL3408018) Show SMILES C1CN=C(Nc2cnc3CCCCc3c2)N1 Show InChI InChI=1S/C12H16N4/c1-2-4-11-9(3-1)7-10(8-15-11)16-12-13-5-6-14-12/h7-8H,1-6H2,(H2,13,14,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.23E+3	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070099 (CHEMBL3408019) Show SMILES CCNc1ccc(NC2=NCCN2)cn1 Show InChI InChI=1S/C10H15N5/c1-2-11-9-4-3-8(7-14-9)15-10-12-5-6-13-10/h3-4,7H,2,5-6H2,1H3,(H,11,14)(H2,12,13,15)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.71E+3	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070098 (CHEMBL3408028) Show SMILES N=C(NCc1ccco1)Nc1ccc2CCCCc2n1 Show InChI InChI=1S/C15H18N4O/c16-15(17-10-12-5-3-9-20-12)19-14-8-7-11-4-1-2-6-13(11)18-14/h3,5,7-9H,1-2,4,6,10H2,(H3,16,17,18,19)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (Homo sapiens (Human))	BDBM50070081 (CHEMBL3408032) Show SMILES OCCNC1=NCc2ccccc2N1 Show InChI InChI=1S/C10H13N3O/c14-6-5-11-10-12-7-8-3-1-2-4-9(8)13-10/h1-4,14H,5-7H2,(H2,11,12,13)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.03E+4	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Antagonist activity at human alpha-2 adrenergic receptor in brain prefrontal cortex membrane assessed as inhibition of UK14304-induced [35S]-GTPgamma...				J Med Chem 58: 963-77 (2015) Article DOI: 10.1021/jm501635e BindingDB Entry DOI: 10.7270/Q280549P
					More data for this Ligand-Target Pair