Found 35 Enz. Inhib. hit(s) with all data for entry = 7658 TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 54nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 65nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 80nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 85nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 100nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 150nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 370nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 500nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 570nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 2.10E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 3.20E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 6.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 7.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President And Fellows Of Harvard College
US Patent
President And Fellows Of Harvard College
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
