Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50008735
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50403733(CHEMBL1206880 | CL-191121)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076671((4R,6S)-3-{(2R,3R)-2-[((S)-1-Carboxy-2-methyl-prop...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076671((4R,6S)-3-{(2R,3R)-2-[((S)-1-Carboxy-2-methyl-prop...)
Affinity DataIC50:  91nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076673(CHEMBL175189 | Sodium; (2S,5R,6R)-6-((S)-1-hydroxy...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50403733(CHEMBL1206880 | CL-191121)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076678((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076674(CHEMBL177772 | Sodium; (2S,5R,6S)-6-((S)-1-hydroxy...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076672((2S,5R,6S)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076677(CHEMBL177912 | Sodium; (2S,5R,6S)-6-((R)-1-hydroxy...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076675(CHEMBL265722 | Sodium; (2S,5R,6R)-6-hydroxymethyl-...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  4.77E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076677(CHEMBL177912 | Sodium; (2S,5R,6S)-6-((R)-1-hydroxy...)
Affinity DataIC50:  4.79E+4nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076676(CHEMBL177463 | Sodium; (2S,5R,6S)-6-hydroxymethyl-...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  6.59E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076675(CHEMBL265722 | Sodium; (2S,5R,6R)-6-hydroxymethyl-...)
Affinity DataIC50:  6.59E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076673(CHEMBL175189 | Sodium; (2S,5R,6R)-6-((S)-1-hydroxy...)
Affinity DataIC50:  2.04E+5nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076676(CHEMBL177463 | Sodium; (2S,5R,6S)-6-hydroxymethyl-...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076674(CHEMBL177772 | Sodium; (2S,5R,6S)-6-((S)-1-hydroxy...)
Affinity DataIC50: >3.34E+5nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed