Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50035189
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataKi:  2.30nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  2.30nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096712(3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...)
Affinity DataKi:  6.40nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  6.90nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096711(CHEMBL320963 | Indole-1-carboxylic acid 1-aza-bicy...)
Affinity DataKi:  8.80nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  220nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  480nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096712(3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...)
Affinity DataKi:  2.30E+3nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi: >3.00E+3nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096712(3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  5.50E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096712(3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...)
Affinity DataKi:  7.80E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096711(CHEMBL320963 | Indole-1-carboxylic acid 1-aza-bicy...)
Affinity DataKi:  1.40E+4nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  1.60E+4nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  2.70E+4nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma delta nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi:  3.80E+4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  4.60E+4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  5.50E+4nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi:  6.70E+4nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataEC50:  580nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  3.80E+4nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Affinity DataEC50:  2.30E+5nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096712(3-(1H-Indole-3-carbonyloxy)-8,8-dimethyl-8-azonia-...)
Affinity DataEC50:  280nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50096711(CHEMBL320963 | Indole-1-carboxylic acid 1-aza-bicy...)
Affinity DataEC50:  4.80E+3nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed