Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50005965
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.0400nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.110nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Affinity DataKi:  0.120nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.470nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.570nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Affinity DataKi:  1.90nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  22nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataIC50:  1.80nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataIC50:  3.40nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataIC50:  5.40nMAssay Description:Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50:  47nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed