Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50011405
LigandPNGBDBM50106179(CHEMBL125327 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...)
Affinity DataIC50:  2nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106169(CHEMBL338973 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...)
Affinity DataIC50:  9nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106167(CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...)
Affinity DataIC50:  18nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106167(CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...)
Affinity DataIC50:  18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106178(4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...)
Affinity DataIC50:  23nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106168(CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  27nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106168(CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50061218((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...)
Affinity DataIC50:  31nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106176(CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106176(CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  40nMAssay Description:Bindind affinity values obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106182(CHEMBL123085 | N-(3,3-Dimethyl-butyl)-4-(3-phenyl-...)
Affinity DataIC50:  130nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106166(CHEMBL122341 | N-(3,3-Dimethyl-butyl)-4-hexyloxy-b...)
Affinity DataIC50:  250nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106177(CHEMBL431682 | N-(3,3-Dimethyl-butyl)-4-indol-1-yl...)
Affinity DataIC50:  260nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106184(CHEMBL121751 | N-(3,3-Dimethyl-cyclopentyl)-4-hexy...)
Affinity DataIC50:  360nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106180(CHEMBL124595 | N-(3,3-Dimethyl-cyclohexylmethyl)-4...)
Affinity DataIC50:  370nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106181(Biphenyl-4-carboxylic acid (3,3-dimethyl-butyl)-am...)
Affinity DataIC50:  540nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106164(CHEMBL123569 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  580nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106164(CHEMBL123569 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  580nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106175(CHEMBL121750 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  710nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106175(CHEMBL121750 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)
Affinity DataIC50:  710nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106174(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)
Affinity DataIC50:  1.40E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106165((3-tert-Butyl-pyrrolidin-1-yl)-(4-hexyloxy-phenyl)...)
Affinity DataIC50: >3.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106174(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)
Affinity DataIC50: >3.00E+3nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106170(CHEMBL122865 | N-(2-Diethylamino-ethyl)-4-hexyloxy...)
Affinity DataIC50:  3.50E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106183(1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106173(CHEMBL341368 | N,N-Diethyl-2-[4-(1,1,3,3-tetrameth...)
Affinity DataIC50:  5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106171(CHEMBL122637 | Diethyl-{2-[4-(1,1,3,3-tetramethyl-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106172(CHEMBL340222 | N-(2,2-Dimethyl-cyclopentyl)-4-hexy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed