Affinity DataKi: 109nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of fluorescent P4 peptide from MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
Affinity DataKi: 916nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+3nMAssay Description:Inhibition of beta-catenin/T cell factor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.36E+3nMAssay Description:Competitive binding affinity to human beta-catenin (142 to 686) assessed as inhibition of C-terminally fluorescein-labeled Tcf4 interaction after 3 h...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of fluorescent P4 peptide from MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.14E+3nMAssay Description:Competitive binding affinity to human beta-catenin (142 to 686) assessed as inhibition of C-terminally fluorescein-labeled Tcf4 interaction after 3 h...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from VHL/elongins-B/elonginC (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.17E+5nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+3nMAssay Description:Binding affinity to IFNAR (unknown origin) assessed as inhibition of interaction with IFN-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+7nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from VHL/elongins-B/elonginC (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair