Compile Data Set for Download or QSAR
maximum 50k data
Found 110 Enz. Inhib. hit(s) with all data for entry = 50015141
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151969(3-{4-[4-(2-Cyano-3-fluoro-phenyl)-piperazin-1-yl]-...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151976(3-{4-[4-(2,4-Dimethoxy-phenyl)-piperazin-1-yl]-but...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151946(3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151937(3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151978(3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151954(3-{4-[4-(4-Acetylamino-phenyl)-piperazin-1-yl]-but...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151932(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151966(3-{4-[4-(4-Hydroxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151933(3-{4-[4-(2-Cyano-phenyl)-piperazin-1-yl]-butyl}-1H...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151948(3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pipera...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151950(3-{4-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-butyl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151962(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151930(3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151957(3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151938(4-{1-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-1,2,3,6-t...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151958(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151952(3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pipera...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151943(Acetic acid 3-{4-[4-(4-methoxy-phenyl)-piperazin-1...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151971(3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-1H-ind...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151934(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-3,6-dihydro-2...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151973(3-{4-[4-(3,5-Dichloro-4-methoxy-phenyl)-piperazin-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151953(3-{4-[4-(4-Ethoxy-phenyl)-piperazin-1-yl]-butyl}-5...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151960(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indol-5-o...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50002173(3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151945(3-{4-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-butyl...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151940(3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-ph...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151964(3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indol-5-o...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151972(Acetic acid 4-{4-[4-(5-methoxy-1H-indol-3-yl)-buty...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151937(3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151975(5-Methoxy-3-(4-{4-[4-(2-methoxy-ethoxy)-phenyl]-pi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151955(4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151942(5-Ethoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151951(3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-5-meth...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151939(CHEMBL364150 | N-(4-{4-[4-(5-Methoxy-1H-indol-3-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151935(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  4nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151961(3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  4nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151960(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indol-5-o...)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151969(3-{4-[4-(2-Cyano-3-fluoro-phenyl)-piperazin-1-yl]-...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50002173(3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151933(3-{4-[4-(2-Cyano-phenyl)-piperazin-1-yl]-butyl}-1H...)
Affinity DataIC50:  6.20nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151932(3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151974(3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151931(3-{4-[4-(3,4-Dimethoxy-phenyl)-piperazin-1-yl]-but...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151978(3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151956(5-Methoxy-3-[4-(4-phenyl-piperazin-1-yl)-butyl]-1H...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151949(3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151930(3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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