Compile Data Set for Download or QSAR
maximum 50k data
Found 95 Enz. Inhib. hit(s) with all data for entry = 50045318
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  4nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056506(CHEMBL3341943 | US10688093, Compound 382_0087_6488...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056507(CHEMBL3341944)
Affinity DataIC50:  6nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056510(CHEMBL3341947)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056675(CHEMBL3341787)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  16nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056507(CHEMBL3341944)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056684(CHEMBL3341941 | US10688093, Compound 382_0087_7249...)
Affinity DataIC50:  20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056509(CHEMBL3341946)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056676(CHEMBL3341789)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056676(CHEMBL3341789)
Affinity DataIC50:  27nMAssay Description:Inhibition of ALK2 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056676(CHEMBL3341789)
Affinity DataIC50:  27nMAssay Description:Inhibition of ALK1 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  27nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  30nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056675(CHEMBL3341787)
Affinity DataIC50:  30nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056510(CHEMBL3341947)
Affinity DataIC50:  40nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056507(CHEMBL3341944)
Affinity DataIC50:  49nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056506(CHEMBL3341943 | US10688093, Compound 382_0087_6488...)
Affinity DataIC50:  60nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056549(CHEMBL3341952)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056511(CHEMBL3341948)
Affinity DataIC50:  86nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056685(CHEMBL3341942)
Affinity DataIC50:  90nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056676(CHEMBL3341789)
Affinity DataIC50:  100nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  100nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056674(CHEMBL3341953)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056678(CHEMBL3341792)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056511(CHEMBL3341948)
Affinity DataIC50:  110nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056507(CHEMBL3341944)
Affinity DataIC50:  110nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056677(CHEMBL3341791)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056509(CHEMBL3341946)
Affinity DataIC50:  140nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056506(CHEMBL3341943 | US10688093, Compound 382_0087_6488...)
Affinity DataIC50:  180nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056508(CHEMBL3341945)
Affinity DataIC50:  186nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056675(CHEMBL3341787)
Affinity DataIC50:  240nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056675(CHEMBL3341787)
Affinity DataIC50:  240nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056675(CHEMBL3341787)
Affinity DataIC50:  250nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056683(CHEMBL3341795)
Affinity DataIC50:  260nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056506(CHEMBL3341943 | US10688093, Compound 382_0087_6488...)
Affinity DataIC50:  260nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056679(CHEMBL3341793)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056687(CHEMBL3341954)
Affinity DataIC50:  280nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  280nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  340nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056549(CHEMBL3341952)
Affinity DataIC50:  360nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056681(CHEMBL3341788)
Affinity DataIC50:  370nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056677(CHEMBL3341791)
Affinity DataIC50:  410nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  420nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056679(CHEMBL3341793)
Affinity DataIC50:  470nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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