Compile Data Set for Download or QSAR
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Found 45 Enz. Inhib. hit(s) with all data for entry = 50016060
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.800nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  1.04nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  1.07nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi:  1.12nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  1.19nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoro-...)
Affinity DataKi:  1.46nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  1.83nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  3.58nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  30nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  70.2nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  71.3nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  80.9nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoro-...)
Affinity DataKi:  142nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi:  179nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  320nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  505nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  518nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  664nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  787nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  946nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  1.35E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  2.12E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi:  2.18E+3nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  2.91E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi:  3.55E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  3.61E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  3.82E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  3.91E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  4.33E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  4.43E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  4.44E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi:  5.13E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  5.30E+3nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi:  7.04E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  7.55E+3nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoro-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed