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Compile Data Set for Download or QSAR

Found 69 hits Enz. Inhib. hit(s) with all data for entry = 50008738   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (Human))
BDBM18161
PNG
((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
Show InChI InChI=1/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/s2
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2n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Androgen Receptor


(Homo sapiens (Human))
BDBM50076700
PNG
((6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-8(2)19-12-6-13-10(4-9(7)12)11(15(16,17)18)5-14(21)20-13/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1
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6n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076717
PNG
((R)-8-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES C[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C14H13F3N2O/c1-7-2-3-8-4-9-10(14(15,16)17)5-13(20)19-12(9)6-11(8)18-7/h4-7,18H,2-3H2,1H3,(H,19,20)/t7-/m1/s1
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7n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076707
PNG
((R)-8-Ethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Show SMILES CC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-2-9-4-3-8-5-10-11(15(16,17)18)6-14(21)20-13(10)7-12(8)19-9/h5-7,9,19H,2-4H2,1H3,(H,20,21)/t9-/m1/s1
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8n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076708
PNG
((6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@@H]1C[C@H](CC)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10(4-2)21-14-8-15-12(6-11(9)14)13(17(18,19)20)7-16(23)22-15/h6-10,21H,3-5H2,1-2H3,(H,22,23)/t9-,10+/m0/s1
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9n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076713
PNG
((7S,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m1/s1
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11n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076703
PNG
((7R,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12-/m1/s1
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11n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076711
PNG
((7S,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12+/m0/s1
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12n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076706
PNG
((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9-/m1/s1
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15n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076701
PNG
((7R,8R)-7,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-9-4-10-11(15(16,17)18)5-14(21)20-13(10)6-12(9)19-8(7)2/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8-/m1/s1
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15n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076720
PNG
((7S,8R)-7,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10-6-11-12(17(18,19)20)7-16(23)22-15(11)8-14(10)21-13(9)4-2/h6-9,13,21H,3-5H2,1-2H3,(H,22,23)/t9-,13+/m0/s1
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16n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076710
PNG
((6S,8R)-8-Ethyl-6-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-8(2)10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-9/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m0/s1
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21n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076716
PNG
((7S,8R)-7,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-9-4-10-11(15(16,17)18)5-14(21)20-13(10)6-12(9)19-8(7)2/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1
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22n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076704
PNG
((6S,8R)-6-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1C[C@@H](C)Nc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-8(2)20-13-7-14-11(5-10(9)13)12(16(17,18)19)6-15(22)21-14/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m1/s1
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23n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076702
PNG
((R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-2-3-10-5-4-9-6-11-12(16(17,18)19)7-15(22)21-14(11)8-13(9)20-10/h6-8,10,20H,2-5H2,1H3,(H,21,22)/t10-/m1/s1
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24n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50063127
PNG
(8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES CC1(C)CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(21)19-12(9)7-11(8)20-14/h5-7,20H,3-4H2,1-2H3,(H,19,21)
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26n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50403732
PNG
(CHEMBL2112349)
Show SMILES CC(C)(O)C(=O)Nc1ccc(c(c1O)C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C11H11F3N2O5/c1-10(2,19)9(18)15-5-3-4-6(16(20)21)7(8(5)17)11(12,13)14/h3-4,17,19H,1-2H3,(H,15,18)
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27n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076705
PNG
((7R,8R)-7,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10-6-11-12(17(18,19)20)7-16(23)22-15(11)8-14(10)21-13(9)4-2/h6-9,13,21H,3-5H2,1-2H3,(H,22,23)/t9-,13-/m1/s1
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29n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076712
PNG
((7S,8R)-8-Ethyl-7-propyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CCC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C18H21F3N2O/c1-3-5-10-6-11-7-12-13(18(19,20)21)8-17(24)23-16(12)9-15(11)22-14(10)4-2/h7-10,14,22H,3-6H2,1-2H3,(H,23,24)/t10-,14+/m0/s1
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32n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076718
PNG
((R)-7,7,8-Triethyl-4-trifluoromethyl-6,7,8,9-tetra...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F
Show InChI InChI=1S/C19H23F3N2O/c1-4-16-18(5-2,6-3)10-11-7-12-13(19(20,21)22)8-17(25)24-15(12)9-14(11)23-16/h7-9,16,23H,4-6,10H2,1-3H3,(H,24,25)/t16-/m1/s1
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42n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076715
PNG
((R)-8-Ethyl-7,7-dimethyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-4-14-16(2,3)8-9-5-10-11(17(18,19)20)6-15(23)22-13(10)7-12(9)21-14/h5-7,14,21H,4,8H2,1-3H3,(H,22,23)/t14-/m1/s1
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50n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076709
PNG
((R)-7,7,8-Trimethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-8-15(2,3)7-9-4-10-11(16(17,18)19)5-14(22)21-13(10)6-12(9)20-8/h4-6,8,20H,7H2,1-3H3,(H,21,22)/t8-/m1/s1
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82n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076714
PNG
((S)-8-Isopropyl-4-trifluoromethyl-6,7,8,9-tetrahyd...)
Show SMILES CC(C)[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-8(2)12-4-3-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t12-/m0/s1
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109n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076711
PNG
((7S,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12+/m0/s1
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n/an/a 11n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076707
PNG
((R)-8-Ethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Show SMILES CC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-2-9-4-3-8-5-10-11(15(16,17)18)6-14(21)20-13(10)7-12(8)19-9/h5-7,9,19H,2-4H2,1H3,(H,20,21)/t9-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076700
PNG
((6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-8(2)19-12-6-13-10(4-9(7)12)11(15(16,17)18)5-14(21)20-13/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076703
PNG
((7R,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12-/m1/s1
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n/an/a 15n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50403732
PNG
(CHEMBL2112349)
Show SMILES CC(C)(O)C(=O)Nc1ccc(c(c1O)C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C11H11F3N2O5/c1-10(2,19)9(18)15-5-3-4-6(16(20)21)7(8(5)17)11(12,13)14/h3-4,17,19H,1-2H3,(H,15,18)
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n/an/a 15n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076717
PNG
((R)-8-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES C[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C14H13F3N2O/c1-7-2-3-8-4-9-10(14(15,16)17)5-13(20)19-12(9)6-11(8)18-7/h4-7,18H,2-3H2,1H3,(H,19,20)/t7-/m1/s1
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n/an/a 19n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076709
PNG
((R)-7,7,8-Trimethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-8-15(2,3)7-9-4-10-11(16(17,18)19)5-14(22)21-13(10)6-12(9)20-8/h4-6,8,20H,7H2,1-3H3,(H,21,22)/t8-/m1/s1
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n/an/a 24n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076714
PNG
((S)-8-Isopropyl-4-trifluoromethyl-6,7,8,9-tetrahyd...)
Show SMILES CC(C)[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-8(2)12-4-3-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t12-/m0/s1
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n/an/a 25n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50063127
PNG
(8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES CC1(C)CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(21)19-12(9)7-11(8)20-14/h5-7,20H,3-4H2,1-2H3,(H,19,21)
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n/an/a 27n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076702
PNG
((R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-2-3-10-5-4-9-6-11-12(16(17,18)19)7-15(22)21-14(11)8-13(9)20-10/h6-8,10,20H,2-5H2,1H3,(H,21,22)/t10-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076716
PNG
((7S,8R)-7,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-9-4-10-11(15(16,17)18)5-14(21)20-13(10)6-12(9)19-8(7)2/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1
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n/an/a 33n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076715
PNG
((R)-8-Ethyl-7,7-dimethyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-4-14-16(2,3)8-9-5-10-11(17(18,19)20)6-15(23)22-13(10)7-12(9)21-14/h5-7,14,21H,4,8H2,1-3H3,(H,22,23)/t14-/m1/s1
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n/an/a 42n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076718
PNG
((R)-7,7,8-Triethyl-4-trifluoromethyl-6,7,8,9-tetra...)
Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F
Show InChI InChI=1S/C19H23F3N2O/c1-4-16-18(5-2,6-3)10-11-7-12-13(19(20,21)22)8-17(25)24-15(12)9-14(11)23-16/h7-9,16,23H,4-6,10H2,1-3H3,(H,24,25)/t16-/m1/s1
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n/an/a 48n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076701
PNG
((7R,8R)-7,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Show SMILES C[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2O/c1-7-3-9-4-10-11(15(16,17)18)5-14(21)20-13(10)6-12(9)19-8(7)2/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8-/m1/s1
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n/an/a 74n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076710
PNG
((6S,8R)-8-Ethyl-6-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-8(2)10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-9/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m0/s1
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n/an/a 137n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076713
PNG
((7S,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m1/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076720
PNG
((7S,8R)-7,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10-6-11-12(17(18,19)20)7-16(23)22-15(11)8-14(10)21-13(9)4-2/h6-9,13,21H,3-5H2,1-2H3,(H,22,23)/t9-,13+/m0/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM18161
PNG
((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
Show InChI InChI=1/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/s2
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n/an/a>1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Androgen Receptor


(Homo sapiens (Human))
BDBM50076706
PNG
((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9-/m1/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076705
PNG
((7R,8R)-7,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10-6-11-12(17(18,19)20)7-16(23)22-15(11)8-14(10)21-13(9)4-2/h6-9,13,21H,3-5H2,1-2H3,(H,22,23)/t9-,13-/m1/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076712
PNG
((7S,8R)-8-Ethyl-7-propyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CCC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C18H21F3N2O/c1-3-5-10-6-11-7-12-13(18(19,20)21)8-17(24)23-16(12)9-15(11)22-14(10)4-2/h7-10,14,22H,3-6H2,1-2H3,(H,23,24)/t10-,14+/m0/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076704
PNG
((6S,8R)-6-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1C[C@@H](C)Nc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-8(2)20-13-7-14-11(5-10(9)13)12(16(17,18)19)6-15(22)21-14/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m1/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076708
PNG
((6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Show SMILES CC[C@@H]1C[C@H](CC)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-3-9-5-10(4-2)21-14-8-15-12(6-11(9)14)13(17(18,19)20)7-16(23)22-15/h6-10,21H,3-5H2,1-2H3,(H,22,23)/t9-,10+/m0/s1
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n/an/a<1.00E+4n/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cells; no data


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076712
PNG
((7S,8R)-8-Ethyl-7-propyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CCC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1CC)C(F)(F)F
Show InChI InChI=1S/C18H21F3N2O/c1-3-5-10-6-11-7-12-13(18(19,20)21)8-17(24)23-16(12)9-15(11)22-14(10)4-2/h7-10,14,22H,3-6H2,1-2H3,(H,23,24)/t10-,14+/m0/s1
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n/an/an/an/a 16n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076717
PNG
((R)-8-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Show SMILES C[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F
Show InChI InChI=1S/C14H13F3N2O/c1-7-2-3-8-4-9-10(14(15,16)17)5-13(20)19-12(9)6-11(8)18-7/h4-7,18H,2-3H2,1H3,(H,19,20)/t7-/m1/s1
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n/an/an/an/a 21n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076713
PNG
((7S,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9+/m1/s1
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n/an/an/an/a 9n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50076706
PNG
((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Show SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F
Show InChI InChI=1S/C16H17F3N2O/c1-3-9-4-10-5-11-12(16(17,18)19)6-15(22)21-14(11)7-13(10)20-8(9)2/h5-9,20H,3-4H2,1-2H3,(H,21,22)/t8-,9-/m1/s1
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n/an/an/an/a 10n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines


Bioorg Med Chem Lett 9: 1009-12 (1999)


Article DOI: 10.1016/s0960-894x(99)00119-5
BindingDB Entry DOI: 10.7270/Q2F18XWV
More data for this
Ligand-Target Pair
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