Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50030333
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294557((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 at 45 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294574((2S,4S)-4-(((2S,3S,4R,5S)-5-(6-amino-2-chloro-9H-p...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294577((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294557((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294559((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294574((2S,4S)-4-(((2S,3S,4R,5S)-5-(6-amino-2-chloro-9H-p...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294577((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294562((2S,4S)-methyl 4-(((2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294564((2S,4S)-methyl 4-(((2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294565((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-py...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294556((2S,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-2...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294559((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294567((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294563((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294565((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-py...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294555((2R,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-9...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294572((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((3-amin...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294573((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((2-amin...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294568((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((S)-py...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294569((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-py...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294566((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((S)-py...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294556((2S,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-2...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294569((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-py...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294555((2R,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-9...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294575((2S,3R,4S,5S)-2-(6-amino-2-chloro-9H-purin-9-yl)-5...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294560((2S,4R)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294573((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((2-amin...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294571((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((azetid...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294566((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((S)-py...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294575((2S,3R,4S,5S)-2-(6-amino-2-chloro-9H-purin-9-yl)-5...)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294572((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((3-amin...)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294558((2S,4R)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294570((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((1R,2S...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294570((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((1R,2S...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294558((2S,4R)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294560((2S,4R)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294561((2R,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294561((2R,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294568((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((S)-py...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294563((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294571((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((azetid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed