Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50030684
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300114((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300115((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300116((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM31202(JMC493432 Compound 8 | MI-63)
Affinity DataKi:  1.70nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300118((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataKi:  2nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300117((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataKi:  4nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300119((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300121((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataKi:  13.1nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300120((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataKi:  15.4nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300114((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataIC50:  16.4nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300116((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM31202(JMC493432 Compound 8 | MI-63)
Affinity DataIC50:  28.3nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300118((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataIC50:  32.4nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300115((2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophe...)
Affinity DataIC50:  32.4nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300117((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataIC50:  56nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300122((11S,14S,20S,23S,26S)-11-benzyl-23-((6-chloro-1H-i...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to his-tagged human recombinant MDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300119((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataIC50:  157nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300121((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataIC50:  162nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50300120((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataIC50:  189nMAssay Description:Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed